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简介：AbstractBackground:The diagnosis of contrast-induced nephropathy (CIN) is usually based on changes in serum creatinine (sCr). However, sCr has poor sensitivity as a biomarker of kidney injury. The aim of this study was to investigate the usefulness of serum cystatin C (sCysC) to predict CIN after intra-arterial interventions.Methods:A total of 360 consecutive patients underwent intra-arterial procedures using digital subtraction angiography. SCr, sCysC, and estimated glomerular filtration rate were measured at 1 to 2 days before and at 48, 72 h, and 7 days after the procedure.Results:Thirty-one patients (8.61%) developed CIN. Receiver operating characteristic (ROC) curve analysis showed that preoperative sCysC levels had good discriminatory power (area under the curve [AUC] = 0.634; 95% confidence interval [CI] = 0.526-0.743) for evaluating the risk of CIN after an endovascular procedure, with a sensitivity of 53.33% and specificity of 73.70%. ROC analysis showed that sCysC at 48 h after contrast medium administration was predictive of CIN after an endovascular procedure (AUC = 0.735; 95% CI = 0.647-0.822) with satisfactory sensitivity of 74.20% and specificity of 63.90%. Diabetes mellitus was an independent risk factor for CIN (odds ratio = 2.778; 95% CI = 1.045-7.382; P = 0.040).Conclusions:SCysC is an appropriate biomarker to predict the occurrence of CIN. Baseline sCysC before an intervention is useful to obtain a preliminary estimate of the risk of CIN. A 48-h cut-off value of sCysC of 0.99 mg/L after an endovascular procedure may help to rule out patients at lower risk of CIN.

简介：Earthquakedisasterrisk,asatypicalsocialdisasterrisk,isoneofthemostimportantrisksinmodernChinesesociety.Thisstudygivesdefinitionsoftheinstitution,describestheformationhistory,theconnotationsanddevelopmentandanalyzesitsroleinthecontrolofmajorsocialriskscausedbyearthquakes.Finally,thepaperpresentsrecommendationsforcontinuousimprovementofthisinstitutionundertheguidanceofrisksocietytheory,andforitsapplicationtothegovernmentreformandsocialgovernance.

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简介：Thespectrumofisospin3/2Δ++(1232)excitedstatesisoneofthemostimportantissuesinhadronicphysicsandisattractingmuchattentionbecauseitisthemostexperimentallyaccessiblesystemcomposedofthreeidenticalvalencequarks.However,ourknowledgeontheseresonancesmainlycomesfromoldNexperimentsandisstillverypoor[1].Intheenergyregionaroundorabove2.0GeV,therearestillmanytheoreticalpredictionsofmissingΔstateswhichhavesofarnotbeenobserved.Searchingforthesemissingstatesfromotherproductionprocessesisnecessary.ApossiblenewexcellentsourceforstudyingtheseΔresonancecomprisesthe+p!K+Σ+(1385)andpp!nK+Σ+(1385)reactions,whichhaveaspecialadvantage,i:e:,thereisnocontributionsfromisospin1/2nucleonresonancesduetotheisospinandchargeconservations.

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简介：瞄准：评估对在有动脉的可勃起的机能障碍(编辑)的病人的sildenafil管理的反应是否与他们的山峰有关收缩速度(PSV)，外部动脉粥样硬化，心血管的风险因素(RF)或在低心血管的风险的comorbidities。方法：我们与12RF和comorbidities注册了97个病人，独自与动脉的编辑结合了(组A，n=27)，编辑正动脉粥样硬化患者颈动脉动脉(组B，n=23)，编辑正更低的手足动脉畸形(组C，n=25)，并且编辑正颈动脉和更低的手足动脉畸形(组D，n=22)。Sildenafil功效(100mg两次为12个星期的一个星期)也与≥在病人被检验3RF，外部动脉粥样硬化和没有心血管的comorbidities(组E，n=20)。结果：中部的PSV分别地是在组A，B，C，D和E的24.1，21.0，19.3，14.5和17.5cm/s。Sildenafil反应在组A是更高的病人(77.8%)，在组B和C(65.2%和56%)中间、在组最低D(45.4%)和E(50%)，和在后者二组的反应比在另外的三个组显著地低。另外，sildenafil反应否定地旁边被影响：≥3RF，外部动脉粥样硬化和没有全身的comorbidity，或与扩大动脉粥样硬化和comorbidities联系的12RF的存在。comorbidities的数字是断然与动脉粥样硬化本地化或扩展有关(25，35，38和47在组A，B，C和D，分别地)。结论：在有动脉的编辑的病人的低sildenafil功效与扩大动脉粥样硬化被联系。这些病人应该经历广泛的ultrasonography和完整的心血管的考试。

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简介：Acuteaorticsyndromeincludesclassicaorticdissection,aorticintramuralhematoma,andpenetratingatheroscleroticulcer–agroupofconditionsthataredefinedbytheirdynamicevolutionandsimilarclinicalmanifestation.Accuratediagnosisandprompttreatmentareessentialasalltheaforementionedconditionsareasignificantthreattoapatient’slife.However,acuteaorticsyndromeandespeciallyaorticintramuralhematomamaybechallengingdiagnosticproblems.Intravascularultrasoundimagingisadiagnosticmethodthatcanbeusefulformorethoroughevaluationoftheaorticlesionandcanparticularlyaidindiscerningthedifferentformsofacuteaorticsyndrome.Wepresentacaseofapatientwithaorticintramuralhematomathatwasmissedbyconventionalimagingstudiesbutwassuccessfullyvisualizedwithintravascularultrasoundimaging.

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简介：现在的学习的目的是系统地在成纤维细胞和造骨细胞粘附和增长上评估聚合物crystallinity的角色用一系列poly(caprolactone-co-glycolide)(打印机控制语言/针网阵列)聚合物。自从他们反映高度水晶、非结晶的材料，打印机控制语言/针网阵列聚合物被选择。打印机控制语言/针网阵列聚合材料被塑造进薄电影的压缩制作。从到在25:75，35:65和45:55的比率的打印机控制语言/针网阵列的中间的copolymeric作文的打印机控制语言或针网阵列，五篇作文被学习。当共聚物是非结晶的时，纯打印机控制语言和针网阵列代表了水晶的材料。聚合物/共聚物用DSC被描绘为nanotopography估计crystallinity，为hydrophobicity的接触角度测量，和AFM。而他们在crystallinity显著地不同，打印机控制语言/针网阵列电影表明了类似的hydrophobicity和nanotopography。对的房间粘附和打印机控制语言/针网阵列电影和增长研究上的增长用造骨细胞和NIH-3T3成纤维细胞被执行。高度水晶、僵硬的打印机控制语言和针网阵列表面是，这被观察显著地在支持成纤维细胞生长更有效，而非结晶/灵活的打印机控制语言/针网阵列35:65是显著地在支持造骨细胞的生长更有效。这研究证明当化学作文，hydrophobicity和打印机控制语言/针网阵列聚合物的表面粗糙被保持经常时，打印机控制语言/针网阵列的crystallinity和刚硬在决定房间回答起了主要作用。

简介：在Brassicaceae的摘要，myrosinase催化glucosinolate的水解作用并且在反草食动物防卫起一个重要作用。我们从从另外的Brassica种类与myrosinase基因展出高顺序身份的Brassicaparachinensis克隆并且描绘myrosinase基因的全身的互补DNA。对有菱形斑纹的蛾(Plutellaxylostella)在防卫调查这myrosinase的角色，我们构造了RNA干扰(RNAi)表示指向了myrosinase和transfected的双strandedRNA的盒子它进B。parachinensis。Myrosinase在结果被压制转基因的工厂。在转基因的工厂上喂的有菱形斑纹的蛾幼虫比在非转基因的工厂上喂的那些有更低的幼虫、蛹的重量，更长蛹的持续时间，和更低的肥沃，建议有菱形斑纹的蛾使防御系统适应了glucosinolate-myrosinase。因此，myrosinase的抑制是为控制有菱形斑纹的蛾的一条潜在的途径。

简介：AbstractBackground:Hypertension is associated with stroke-related mortality. However, the long-term association of blood pressure (BP) and the risk of stroke-related mortality and the influence path of BP on stroke-related death remain unknown. The current study aimed to estimate the long-term causal associations between BP and stroke-related mortality and the potential mediating and moderated mediating model of the associations.Methods:This is a 45-year follow-up cohort study and a total of 1696 subjects were enrolled in 1976 and 1081 participants died by the latest follow-up in 2020. COX proportional hazard model was used to explore the associations of stroke-related death with baseline systolic blood pressure (SBP)/diastolic blood pressure (DBP) categories and BP changes from 1976 to 1994. The mediating and moderated mediating effects were performed to detect the possible influencing path from BP to stroke-related deaths. E value was calculated in the sensitivity analysis.Results:Among 1696 participants, the average age was 44.38 ± 6.10 years, and 1124 were men (66.3%). After a 45-year follow-up, a total of 201 (11.9%) stroke-related deaths occurred. After the adjustment, the COX proportional hazard model showed that among the participants with SBP ≥ 160 mmHg or DBP ≥ 100 mmHg in 1976, the risk of stroke-related death increased by 217.5% (hazard ratio [HR] = 3.175, 95% confidence interval [CI]: 2.297-4.388), and the adjusted HRs were higher in male participants. Among the participants with hypertension in 1976 and 1994, the risk of stroke-related death increased by 110.4% (HR= 2.104, 95% CI: 1.632-2.713), and the adjusted HRs of the BP changes were higher in male participants. Body mass index (BMI) significantly mediated the association of SBP and stroke-related deaths and this mediating effect was moderated by gender.Conclusions:In a 45-year follow-up, high BP and persistent hypertension are associated with stroke-related death, and these associations were even more pronounced in male participants. The paths of association are mediated by BMI and moderated by gender.

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简介：当一些血成分在动脉的墙上积累时，一个真神经病的条件经验丰富得到从墙撤退了，再加入循环系统和凝结发生。在使倾向的体环的一个环形的区域的nanofluid的蠕动的流动上的铜nanoparticles和使倾向的磁场的角色被调查。当其外部试管有正弦曲线自然和内胎的一个波浪的一个体环在它的墙上有块，我们由考虑小动脉代表块模型。润滑油途径被用来简化这个问题。靠近的表格答案为温度和速度侧面被决定。在压力上升的相关参数的影响，压力坡度，速度并且优化图形地被解释。在纯血和铜血之中的比较被介绍并且分析。考虑分析的主要发现是铜nanoparticles的包括扩大速度的振幅的。因此，考虑学习在生物医学的应用起一个主导的作用。

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简介：Liquidseparationofmagmaisreferredtoakindofdiffcrentiationofmagmawhichtakesplaceinthecaseofthatmeltsareimmiscibleorlimitedlymiscibleeacliother.Itplaysanimportantroleintheform-ingofbasic,ultrabasicrocksandoredepositsrclatedtotho8ekindsofrocks.Butitisnotsurewhethcritmayoccurintheprocessoftheformingofin

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