简介：Alongwiththeprogressinbreadthanddepthofinternationalarmscontrolanddisarmament,US-ledWesternnationsareincreasinglyinneedofChina’sco-operation.TheybegantoseekconsultationsandcoordinationwithChina.ThishasledtoChina’sbiggersayandrisingroleininternationalarmscontrol.

简介：Inessence,twoepoch-makingeventsarereshapingtheworldordertoday:thecollapseoftheoldSovietblocandtheriseofAsia-Pacific,ofwhichChina’seco-nomictakeoffconstitutesanimportantpart.WhiletheformerbroughtanendtotheEast-WestColdWar,thelatterismakingtremendouscontributionstowards

简介：Nitricoxide(NO)isapleiotropicregulator,criticaltonumerousbiologicalprocesses,includingva-sodilatation,neurotransmissionandmacrophage-mediatedimmunity.Thefamilyofnitricoxidesynthases(NOS)comprisesinducibleNOS(iNOS),endothelialNOS(eNOS),andneuronalNOS(nNOS).Interest-ingly,variousstudieshaveshownthatallthreeisoformscanbeinvolvedinpromotingorinhibitingtheetiologyofcancer.NOSactivityhasbeendetectedintumourcellsofvarioushistogeneticoriginsandhasbeenassociatedwithtumourgrade,proliferationrateandexpressionofimportantsignalingcomponentsassociatedwithcancerdevelopmentsuchastheoestrogenreceptor.ItappearsthathighlevelsofNOSexpression(forexample,generatedbyactivatedmacrophages)maybecytostaticorcytotoxicfortumorcells,whereaslowlevelactivitycanhavetheoppositeeffectandpromotetumourgrowth.Paradoxicallytherefore,NO(andrelatedreactivenitrogenspecies)mayhavebothgenotoxicandangiogenicproperties.IncreasedNO-generationinacellmayselectmutantp53cellsandcontributetotumourangiogenesisbyupregulatingVEGF.Inaddition,NOmaymodulatetumourDNArepairmechanismsbyupregulatingp53,poly(ADP-ribose)polymerase(PARP)andtheDNA-dependentproteinkinase(DNA-PK).Anunderstand-ingatthemolecularleveloftheroleofNOincancerwillhaveprofoundtherapeuticimplicationsforthediagnosisandtreatmentofdisease.

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简介：Coldringrollingisanadvancedbutcomplexmetalformingprocessundercoupledeffectswithmulti-factors,suchasgeometrysizesofrollsandringblank,material,formingprocessparametersandfriction,etc.Amongthesefactors,frictionbetweenrollsandringblankplaysanimportantroleinkeepingthestableformingofcoldringrolling.Ananalyticalmethodwasfirstlypresentedforproximatelydeterminingthecriticalfrictioncoefficientofstableformingandthenamethodwasproposedtodeterminethecriticalfrictioncoefficientbycombininganalyticalmethodwithnumericalsimulation.Andtheinfluenceoffrictioncoefficientonthequalityofend-planeandsidespreadofring,rollingforce,rollingmomentandmetalflowcharacteristicinthecoldringrollingprocesshavebeenexploredusingthethreedimensional(3D)numericalsimulationbasedontheelastic-plasticdynamicfiniteelementmethod(FEM)undertheABAQUSsoftwareenvironment,andtheresultsshowthatincreasingthefrictiononthecontactsurfacesbetweenrollsandringblankisusefulnotonlyforimprovingthestabilityofcoldringrollingbutalsoforimprovingthegeometryanddimensionprecisionofdeformedring.

简介：ＲＯＬＥＯＦＷＯＭＥＮＩＮＳＯＣＩＡＬＦＯＲＥＳＴＲＹＰＲＯＪＥＣＴｂｙＹｕａｎＧｕｏｓｈｅｎｇＳｉｎｃｅｉｔｓｉｍｐｌｅｍｅｎｔａｔｉｏｎｉｎ１９９２，ｔｈｅＦｕｊｉａｎＳｈｏｕｎｉｎｇＳｏｃｉａｌＦｏｒｅｓｔｒｙＰｒｏｊｅｃｔｇｏｖｅｒｎｍｅｎｔ...

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简介：AnumberofresearchprogramshavebeenestablishedtoevaluatepotentialapplicationsofconstructedwetlandsinWesternAustralia.Theseconstructedwetlandsareknownnotonlyfortheirnutrientremovalcapability,butalsotheirroleinhabitatcreation,urbanlandscapingandwaterqualityandenvironmentalhealth.Theyplayanimportantroleinthereductionofnutrients,particularlyphosphorous,fromenteringthewaterways.ThispaperreportsontheimprovementofwaterqualityinthePeelMainDrainbeforeitsdisposalintothePeelEstuary,Perth,WesternAustralia.Thenitrogentophosphorous(N:P)ratiowasbelowthecriticallimitduringsummer(dryspell)andthesystemwaslimitedbynitrogen.Theconcentrationofphosphoruswashighinsummerandlowinwinterduetoincreasedavailabilityofdissolvedoxygeninwinter.AwetlandwasproposedtoimprovethewaterqualityinthePeelMainDrainusingvegetationandsubstrate.Thehydrologiceffectivenesswasfoundtobe78%foradetentiontimeof30hours.Itisexpectedthatthemaximumnitrogenremovalefficiencyoftheconstructedwetlandwillbe80%withanestimatedefficiencyof40%inthefirstyearand60-80%inthesubsequentyears.Forphosphorousitisexpectedthattheconstructedwetlandwillbeeffectiveinremovingfilterablereactivephosphorous.TraditionalsedimentremediationtechniqueshavebeenfoundunsuitableforthelongtermbindingofthephosphorousthereforetheuseofPhoslockTMisrecommended.

简介：Astheprogressofvascularsurgery,artificialvesselshavebecomethesubstituteforlargeandmiddlediametervesselsbuthavenotforsmalldiameteronesowingtothrombogenesisandocclusionwithinashortperiodoftimeafterbeingapplied.ArtificialvesselendothelializationisoneoftheidealmethodstoresolvesuchissueandhasbeenimprovedcontinuouslysinceHerring1in1978putforwardthisterminthefirsttimeandutilizedvascularendothelialcells(ECs)harvestedfromlivinganimalstoperformthetestofartificialvesselendothelialization.

简介：OfflineSoftwaresuchasSimulation,Reconstruction,Analysis,andVisualisationareallinneedofadetectordescription.Theseapplicationshaveseveralcommonbutalsomanyspecificrequirementsforthedetectordescriptioninordertobuilduptheirinternalrepresentations.Toachievethisinaconsistentandcoherentmanneracommonsourceofinformation,thedetectordescriptiondatabase,willbeconsultedbyeachoftheapplications.TheroleandsuitabilityofXMLinthedesignofthedetectordescriptiondatabaseinthescopeoftheCMSdetectorattheLHCisdiscussed.DifferentaspectssuchasdatamodellingcapabilitiesofXML,toolsupport,integrationtoC++representationsofdatamodelsaretreatedandrecentresultsofprototypeimplementationsarepresented.

简介：QiandForm(configuration)arethebasicexistencemannersofallthingsintheUniverse.QiisemphasizedintraditionalChinesemedicineWhileForminWesternmedicine.Itisthemostbasicaldifferencebetweentwotheoreticalsys-temsoftraditionalChineseandWesternmedicine.

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简介：Matrixmetalloproteinases(MMPs)andtissueinhibitorsofmetalloproteinases(TIMPs)playasignificantroleinregulatingangiogenesis,theprocessofnewbloodvesselformation.Interstitialcollagenase(MMP-1),72kDagelatinaseA/typeIVcollagenase(MMP-2),and92kDAgelatinaseB/typeIVcollagenase(MMP-9)dissolveextracellularmatrix(ECM)andmayinitiateandpromoteangiogenesis.TIMP-1,TIMP-2,TIMP-3,andpossibly,TIMP-4inhibitneovascularization.Anewparadignisemergingthatmatrilysin(MMP-7),MMP-9,andmetalloelastase(MMP-12)mayblockangiogenesisbyconvertingplasminogentoangiostatin,whichisoneofthemostpotentangiogenesisantagonists.MMPsandTIMPsplayacomplexroleinregulatingangiogenesis.Anunderstandingofthebiochemicalandcellularpathwaysandmechanismsofangiogenesiswillprovideimportantinformationtoallowthecontrolofangiogenesis,e.g.thestimulationofangiogenesisforcoronarycollateralcirculationformation;whiletheinhibitionfortreatingarthritisandcancer.

简介：ERP is based on the advanced and effective management thoughts and methods. It makes use of new management mode to rebuild old one in one enterprise. The relationship between ERP and the enterprise is supplementary to each other.,3. Embodying the thoughts of pre-planning and controlling during the process 　The planning structure in ERP system includes,which indicates that the company’s decision maker plays a special role during the implementation stage. ERP is the system on management which leads and supervises the entire enterprise. It would have not been effective if the CEO has not approved and authorized the system.

简介：opening to the whole supply chain.Thoughts of ERP system management,achieving the leading position on the market. Applying ERP system into the management of the entire enterprise’s supply chain is the call from the marketing competition in the knowledge economy era.,the process management

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简介：Thetreesinurbanlandscapes,independentofwhethertheyareinurbanforestsorstandalone,canimproveenvironmentquality,enhanceindividualandcommunitywell-being,provideawiderangeofservicestoindividualsandcommunities,andproduceamorehealthfulandcomfortableenvironmentforthevastmajorityofthepopulation.Knowledgeofthepotentialsignificanceoftreesinurbanlandscapesisexpandingrapidlyasresearchcontinuestodocumenttheimportantrolethaturbanforestsandtreescanplayinimprovingthequalityofurbanlife.Theenvironmentalconditionsinurbanlandscapesare,however,verydifferentfromthenaturalconditionsthatthetreespeciesareadaptedto.Thisposesbigchallengestotheurbanforestryinitseffortstocreatehealthyandvaluabletreesinurbanlandscapes.Onlythroughimplementingsomeimportantmeasureswecanensurehighsurvivalrateofsaplingsandwell-beingandlongevityofurbantrees.

简介：六月的第三个星期天是美国的父亲节，但是父亲节是如何起源的呢?节日里有些什么习俗呢?父亲在美国人的心中为什么没有母亲那么伟大呢?请看……

简介：ApoptosisplaysanessentialroleinTcellbiology.ThymocytesexpressingnonfunctionalorautoreactiveTCRsareeliminatedbyapoptosisduringdevelopment.ApoptosisalsoleadstothedeletionofexpandedeffectorTcellsduringimmuneresponses.Thedysregulationofapoptosisintheimmunesystemresultsinautoimmunity,tumorogenesisandimmunodeficiency.Twomajorpathwaysleadtoapoptosis:theintrinsiccelldeathpathwaycontrolledbyBcl-2familymembersandtheextrinsiccelldeathpathwaycontrolledbydeathreceptorsignaling.Thesetwopathwaysworktogethertoregu

简介：Traditionally,bonestructureandbonemassareassessedbyobservingtherari-fiedboneonstandardx-rayfilms.However,smallchangesinbonemasscannotbedetectedeffectively.Bythetimelossofbonemasscanbedetectedonthex-ray,thediseaseisalreadyinanadvancestage.Atleast30%ofbonemustbelostbeforeproblemslikeosteoporosiscanbediagnosed.