简介:Paralysisfollowingspinalcordinjury(SCI)isduetofailureofaxonalregeneration.Itisbelievedthatthecapacitiesofneuronstoregrowtheiraxonsareduepartlytotheirintrinsiccharacteristics,whichinturnaregreatlyinfluencedbyseveraltypesofinhibitorymoleculesthatarepresent,orevenincreasedintheextracellularenvironmentoftheinjuredspinalcord.Manyoftheseinhibitorymoleculeshavebeenstudiedextensivelyinrecentyears.IthasbeensuggestedthatthesmallGTPaseRhoAisanintracellularconvergencepointforsignalingbytheseextracellularinhibitorymolecules,butduetothecomplexityofthecentralnervoussystem(CNS)inmammals,andthelimitationofpharmacologicaltools,thespecificrolesofRhoAareunclear.ByexploitingtheanatomicalandtechnicaladvantagesofthelampreyCNS,werecentlydemonstratedthatRhoAknockdownpromotestrueaxonregenerationthroughthelesionsiteafterSCI.Inaddition,wefoundthatRhoAknockdownprotectsthelarge,identifiedreticulospinalneuronsfromapoptosisaftertheiraxonswereaxotomizedinspinalcord.Therefore,manipulationoftheRhoAsignalingpathwaymaybeanimportantapproachinthedevelopmentoftreatmentsthatarebothneuroprotectiveandaxonregeneration-promoting,toenhancefunctionalrecoveryafterSCI.
简介:Adopting'simultaneoustransmitting,simultaneousreceiving'operationalscheme,instantaneouspolarizationradar(IPR)canmeasuretargetpolarizationscatteringmatrix(PSM)usingonlyoncetargetechoesintwoorthogonalpolarizationchannels.Firstly,signalmodelandsignalprocessareadvancedundernarrowbandcondition.Secondly,measurementperformancesoftwotypicalIPRwaveformsareanalyzedindetail.Atlast,fieldexperimentsarecarriedoutusingX-bandIPRsystemdesignedbyNationalUniversityofDefenseTechnology(NUDT),China.Comparedwithresultsobtainedbyalternativepolarizationmeasurementscheme,followingresultscanbeobtained:thedifferenceofrelativeamplitudemeasurementresultsissmallerthan2dBandthatofrelativephasemeasurementresultsissmallerthan10?,verifyingthevalidityofinstantaneouspolarizationmeasurementscheme.
简介:Thedesignsofinertialconfinementfusion(ICF)targets,whichfieldonShenGuangIII,arebecomingmorecomplexandmorestringentintermsofassemblyprecision.Akeyspecificationofthesetargetsisthespatialanglealignmentaccuracy.Tomeettheseneeds,wepresentanewspatialangleassemblymethod,usingtargetpart's3Dmodel-baseddualorthogonalcameravision,whichisbettersuitedfortheflexibleautomationoftargetassemblyprocesses.Thetwo-handsstructuremicromanipulatesystemanddualorthogonalstructurevisualfeedbacksystemwereinvestigatedbyconsideringthekinematics,spatialanglemeasuring,andmotioncontrolinanintegratedway.Inthispaper,wediscussthemeasurementaccuracyofspatialangleassemblymethod,whichcomparedthereal-timeimageacquisitionwiththeredrawing2Dprojection.Theresultshowsthattheassemblymethodproposedisveryeffectiveandmeetstherequirementsofangleassemblyaccuracy,whichislessthan1°.Also,thisworkisexpectedtocontributegreatlytotheadvancementofothertargetmicroassemblyequipments.
简介:Anovelopticaltestingtarget(OTT)withthreedegreesoffreedom(DOFs)isproposedformeasuringthetrackingperformanceofaphotoelectrictheodolite.Themaincomponents,suchastheazimuthaxissystem,thepitchingaxissystem,thelinearmotionsystem,andthesimulatedtargetgenerator,aredesigned.Furthermore,thelinearmodulewiththeformofalarge-spanandlow-stiffnesscantileverbeamisstrengthenedusinganintegratedoptimizationmethod.Afterthestructureisstrengthened,the1st-ordernaturalfrequencyincreasesfrom14Hzto32Hz.Finally,afunctionaltestisperformedandtheresultsshowthatcomparedwithatraditionalopticaltesttarget,thesimulatedtargetgeneratedbythenoveltargetisadvantageousinpractice.
简介:Weproposeimprovedmultilevelfilters(IMLFs)involvingtheabsolutevalueoperationintothealgorithmicframeworkoftraditionalmultilevelfilters(MLFs)toimprovetherobustnessofinfraredsmalltargetenhancementtechniquesunderacomplexinfraredclutteredbackground.Comparedwiththewidelyusedsmalltargetenhancementmethodswhichonlydealwithbrighttargets,theproposedtechniquecanen-hancetheinfraredsmalltarget,whetheritisbrightordark.Experimentalresultsverifythattheproposedtechniqueisefficientandpractical.
简介:Anovelefficienttrackinitiationmethodisproposedfortheharshunderwatertargettrackingenvironment(heavyclutterandlargemeasurementerrors):tracksplitting,evaluating,pruningandmergingmethod(TSEPM).Trackinitiationdemandsthatthemethodshoulddeterminetheexistenceandinitialstateofatargetquicklyandcorrectly.Heavyclutterandlargemeasurementerrorscertainlyposeadditionaldifficultiesandchallenges,whichdeteriorateandcomplicatethetrackinitiationintheharshunderwatertargettrackingenvironment.Therearethreeprimaryshortcomingsforthecurrenttrackinitiationmethodstoinitializeatarget:(a)theycannoteliminatetheturbulencesofcluttereffectively;(b)theremaybeahighfalsealarmprobabilityandlowdetectionprobabilityofatrack;(c)theycannotestimatetheinitialstateforanewconfirmedtrackcorrectly.Basedonthemultiplehypothesestrackingprincipleandmodifiedlogic-basedtrackinitiationmethod,inordertoincreasethedetectionprobabilityofatrack,tracksplittingcreatesalargenumberoftrackswhichincludethetruetrackoriginatedfromthetarget.Andinordertodecreasethefalsealarmprobability,basedontheevaluationmechanism,trackpruningandtrackmergingareproposedtoreducethefalsetracks.TSEPMmethodcandealwiththetrackinitiationproblemsderivedfromheavyclutterandlargemeasurementerrors,determinethetarget’sexistenceandestimateitsinitialstatewiththeleastsquaresmethod.What'smore,ourmethodisfullyautomaticanddoesnotrequireanykindmanualinputforinitializingandtuninganyparameter.Simulationresultsindicatethatournewmethodimprovessignificantlytheperformanceofthetrackinitiationintheharshunderwatertargettrackingenvironment.
简介:Abasicassumptionofmostrecentlyproposedwaveformdesignalgorithmsisthatthetargetimpulseresponseisaknowndeterministicfunctionorastochasticprocesswithaknownpowerspectraldensity(PSD).However,itiswell-knownthatatargetimpulseresponseisneithereasilynoraccuratelyobtained;besidesitchangessharplywithattitudeangles.Bothoftheaforementionedcasescomplicatethewaveformdesignprocess.Inthispaper,anadaptiverobustwaveformselectionmethodforunknowntargetdetectioninclutterisproposed.Thetargetimpulseresponseisconsideredtobeunknownbutbelongstoaknownuncertaintyset.Anadaptivewaveformlibraryisdevisedbyusingasignal-to-clutter-plus-noiseratio(SCNR)-basedoptimalwaveformdesignmethod.Byapplyingtheminimaxrobustwaveformselectionmethod,theoptimalrobustwaveformisselectedtoensurethelowestperformanceboundoftheunknowntargetdetectioninclutter.Resultsshowthattheadaptivewaveformlibraryoutperformsthepredefinedlinearfrequencymodulation(LFM)waveformlibraryontheSCNRbound.
简介:熔化力量输出不仅与参予反应的燃料粒子数字密度而且到熔化反应率系数成正比(或反应),它依赖于反应物速度分发功能。他们通常被假定是有为热核聚变情形的一样的温度的双Maxwellian分发功能。不管多么高驱动中立横梁注射和少数离子种类ICRF血浆加热,或多拧的血浆横梁迎头向前的碰撞,在收敛,区域在未来被要求并且调查大规模熔化反应堆,当时,源于电离或费用交换的注射精力充沛的快离子尾巴的部分将足够大,他们对non-Maxwellian分发功能的贡献不是可以忽略的,因此评估fu的系数或计算到熔化反应在如此的情况,横梁目标,和横梁横梁反应改进中,效果贡献应该起很重要的作用。在这份报纸,为不同横梁和目标联合情形计算熔化反应率系数的几个有用公式详细被导出。
简介:Theeffectsofdilatationalphasetransformationonthetargetstrengthofceramicmateri-alsareinvestigatedbasedonTate’smodel.Theconstitutivebehaviorofmaterialsindifferentregions(elastic,cracked,plasticandphasetransformation)aretakenintoaccount.Itisfoundthat,withaproperchoiceofmaterialparameters,thedilatationalphasetransformationcanincreaseeffectivelythetargetstrengthR_t.Thiswouldbeofimportanceinpenetration-resistancedesign.
简介:Thehighresolutionradartargetdetectionisaddressedinthenon-Gaussianclutter.Anadaptivedetectorisderivedforrange-spreadtargetbasedonanovelcovariancematrixestimator.Itisprovedthatthenewdetectorisconstantfalsealarmrate(CFAR)tobothofthecluttercovariancematrixstructureandpowerleveltheoreticallyformatchcases.ThesimulationresultsshowthatthenewdetectorisalmostCFARformismatchcases,anditoutperformstheexistingadaptivedetectorbasedonthesamplecovariancematrix.Italsoshowsthatthedetectionperformanceimproves,asthenumberofpulses,thenumberofsecondarydataortheclutterspikeincreases.Inaddition,thederiveddetectorisrobusttodifferentsubsets,estimatedcluttergroupsizesandcorrelationsofclutter.Importantly,thenumberofiterationsforpracticalapplicationisjustone.
简介:Inradartargettrackingapplication,theobservationnoiseisusuallynon-Gaussian,whichisalsoreferredasglintnoise.Theperformancesofconventionaltrackersdegradeseverelyinthepresenceofglintnoise.Animprovedparticlefilter,MarkovchainMonteCarloparticlefilter(MCMC-PF),isappliedtocopewithradartargettrackingwhenthemeasurementsareperturbedbyglintnoise.Trackingperformanceofthefilterisdemonstratedinthepresentofglintnoisebycomputersimulation.