简介:Byexpandingtheperturbationofcovariancematrixinthepowersofer-rorterm,theinfluencefunctionsforfivecanonicalmeasurementsinCCAaredevel-opedandthreesampleversionsaregiven.Forgeneralizedcorrelationcoefficientp_z,theinfluencefunctionisaquadraticformofr.v.z,anditsdistributionisconsidered.ApracticalexampleiUustratestheutilityoftheproposedinfluencefunctions.
简介:Basedonthetheoryofcalculusofvariation,somesuffcientconditionsaregivenforsomeEuler-LagrangcequationstobeequivalentlyrepresentedbyfiniteoreveninfinitemanyHamiltoniancanonicalequations.Meanwhile,somefurtherapplicationsforequationssuchastheKdVequation,MKdVequation,thegenerallinearEulerLagrangeequationandthecylindricshellequationsaregiven.
简介:Irradiationfromdiversesourcesisubiquitousandcloselyassociatedwithhumanactivities.Radiationtherapy(RT),animportantcomponentofmultipleradiationorigins,isacommontherapeuticmodalityforcancer.Moreimportantly,RTprovidessignificantcontributiontooncotherapybykillingtumorcells.However,duringthecourseoftherapy,irradiationofnormaltissuescanresultinawiderangeofsideeffects,includingself-limitedacutetoxicities,mildchronicsymptoms,orsevereorgandysfunction.Althoughnumerouspromisingradioprotectiveagentshaveemerged,onlyafewhavesuccessfullyenteredthemarketbecauseofvariouslimitations.Atpresent,thewidelyacceptedhypothesisforprotectionagainstradiation-causedinjuryinvolvestheWntcanonicalpathway.ActivatingtheWnt/β-cateninsignalingpathwaymayprotectthesalivarygland,oralmucosa,andgastrointestinalepitheliumfromradiationdamage.Theunderlyingmechanismsincludeinhibitingapoptosisandpreservingnormaltissuefunctions.However,aberrantWntsignalingunderliesawiderangeofpathologiesinhumans,anditsvariouscomponentscontributetocancer.Moreover,studieshavesuggestedthatWnt/β-cateninsignalingmayleadtoradioresistanceofcancerstemcell.ThesefactsmarkedlycomplicateanydefinitionoftheexactfunctionoftheWntpathway.
简介:Inthispaper,withPoincare’sformalism,andanindirectmethod,thecanonicalformsofthegeneralizedequationsofmotionduetoNielsenandCenovofaholonomicdynamicalsysteminthevelocity-phasespaceandtheacenleration-phasespaceareobtainedintermsofthePoincareparameters.
简介:我们使用Ringel大厅代数学途径为在Xi被描绘的类型B2的量组学习正规基础元素[12]。然而,我们的途径在那里简化几计算。
简介:Wedesignafamilyof2DH~m-nonconformingfiniteelementsusingthefullP_(2m-3)degreepolynomialspace,forsolving2mthellipticpartialdifferentialequations.Theconsistenterrorisestimatedandtheoptimalorderofconvergenceisproved.Numericaltestsonthenewelementsforsolvingtri-harmonic,4-harmonic,5-harmonicand6-harmonicequationsarepresented,toverifythetheory.
简介:Inthispaper,theGH-congruencecanonicalformsofpositivesemidefiniteanddefinteiniteanddefinite(neednotbeself-conjugate)quaternionmatricesaregiven,andaneccessaryandsufficientconditionofGH-congruencefortwopositivesemidifinite(definite)quaternionmatricesisgivenalso.ThensimultaneousGH-congruencereducedformsfortwoself-conjugatematri-cesandsomeresultaboutthesimultaneousGH-congruencediagonalizationofquaternionmatricesareobtained.
简介:All-opticalcanonicallogicunitsat40Gb/susingbidirectionalfour-wavemixing(FWM)inhighlynonlinearfiberareproposedandexperimentallydemonstrated.Cleartemporalwaveformsandcorrectpatternstreamsaresuccessfullyobservedintheexperiment.Thisschemecanreducetheamountofnonlineardevicesandenlargethecomputingcapacitycomparedwithgeneralones.ThenumericalsimulationsaremadetoanalyzetherelationshipbetweentheFWMefficiencyandthepositionoftwointeractionalsignals.
简介:Canonicalcorelationanalysistolandusestructureanditsdrivingforces———TakingYulinPrefectureasanexampleZHANGMingInstituteofGeog...
简介:TheEinstein'sgeneralrelativityisformulatedintheHamiltonianformforaspatiallyflat,isotropicandhomogeneousuniverse.Subsequently,weperformthecanonicalquantizationproceduretotheHamiltoniantoobtaintheWheeler–DeWittequation.SolvingtheWheeler–DeWittequationandemployingthedeBroglie–Bohminterpretationtothewavefunctionoftheuniverse,weobtainanewversionofspatiallyflatFriedmannequationfortheearlyuniversewherethescalefactoroftheuniverseistakentobesufcientlysmall.
简介:瞄准:调查在肝的卵形的房间在试管内的增长和区别上表明小径的正规Wnt的激活的效果。方法:WB-F344房间与recombinantWnt3a被对待(20,40,80,160,200ng/mL)在24h的没有浆液的媒介。房间增长被Brdu加入分析测量;未经治疗的WB-F344房间作为控制被拿。有为24h的Wnt3a(160ng/mL)的术后疗法,在对待的WB-F344房间代替细胞的本地化和beta-catenin的蛋白质表示并且与Wnt3a未经治疗被免疫荧光染色和西方的污点分析检验。CyclinD1mRNA表示被半量的反向抄本的聚合酶链反应(RT-PCR)决定。一些表型的标记的mRNA层次(法新社,CK-19,白长袍的)并且二个肝的原子因素(HNF-4,HNF-6)被RT-PCR测量。CK-19和法新社蛋白质的表情被西方的污点分析检测。结果:Wnt3a支持了WB-F344房间的增长。有recombinantWnt3a的WB-F344房间的刺激导致了transcriptional使活跃之物beta-catenin的累积,和它进原子核,和起来调整的典型Wnt目标基因CyclinD1的易位。在当浆液不在时的Wnt3a处理的3d以后,WB-F344房间保留了他们的双性人潜力表示hepatocytes和cholangiocytes的几个特定的表型的标记,例如法新社和CK-19,跟随表明小径的正规Wnt的激活。结论:表明小径的正规Wnt支持老鼠的增长和自强肝的卵形的房间。