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简介：AbstractBackground:Cystic echinococcosis is one of the most severe helminth zoonosis with a drastic impact on human health and livestock industry. Investigating optimal control strategy and assessing the crucial factors are essential for developing countermeasures to mitigate this disease.Methods:Two compartment models were formulated to study the dynamics of cystic echinococcosis transmission, to evaluate the effectiveness of various control measures, and to find the optimal control strategy. Sensitive analyses were conducted by obtaining PRCCs and contour plot was used to evaluate the effect of key parameters on the basic reproduction number. Based on forward-backward sweep method, numerical simulations were employed to investigate effects of key factors on the transmission of cystic echinococcosis and to obtain the optimal control strategy.Results:The food resources of stray dog and invalid sheep vaccination rate, which are always neglected, were significant to the transmission and control of cystic echinococcosis. Numerical simulations suggest that, the implementation of optimal control strategy can significantly reduce the infections. Improving the cost of health education and domestic dog deworming could not decrease human infections.Conclusions:Our study showed that only a long-term use of the optimal control measures can eliminate the disease. Meanwhile, during the intervention, sheep vaccination and stray dogs disposing should be emphasized ahead of domestic dogs deworming to minimize the control cost. Simultaneously reducing other wild intermediate hosts and strengthening the sheep vaccination as well as disposing the stray dogs would be most effective.

简介：摘要：本文采用多块BL2100控制器，以上下位机的架构形式，辅以按钮、断路器、继电器、接触器、航空连接器等元器件，实现对加装的测量设备供电及控制，识别加挂的各型吊舱及其供电与控制。采用Dynamic C语言进行编程，采用RS422、RS232等通信方式，解决了逻辑控制问题，完成了各项控制要求。

简介：摘要：电力系统的稳定运行能够为电力用户提供更高质量的电能，从而确保电力供应质量的提高，也更好地满足用户的电力需求。但受电力系统的长时间运行影响，很容易出现故障问题，进而影响到电力用户的正常用电，对此，就需要开展计划停电工作，以开展日常的设备检修及电网升级改造，从而确保电力正常供应，并促进电网的安全可靠运行。但就目前来看，各种停电计划的实施较为复杂，由此很容易出现停电计划描述不清楚的情况，基于此就需要设计一种停电计划任务只能规整及预警辅助工具，这样可以通过应用决策树算法来实现对停电计划的详细描述，以便于更好更快地传达停电计划任务，确保此项工作的顺利开展，并且实现工作质量的提升。本文主要分析了基于决策树算法的停电计划任务智能规整与预警辅助工具，以为停电计划工作开展提供有效支持。

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简介：AbstractBackground:Intravenous thrombolysis (IVT) is an effective way for treating acute ischemic stroke (AIS). However, its effects have not been established among AIS patients with unclear stroke symptoms or with stroke onset for >4.5 h.Methods:We searched PubMed, Embase, Web of Science, Cochrane Central Register of Controlled Trials and Google Scholar databases for randomized controlled trials that compared IVT (IVT group) and placebo or usual care (control group [CG]) in AIS patients with disease onset for >4.5 h. The outcomes of interest included the favorable functional outcome (defined as modified Rankin Scale [mRS] scores 0-1) at 90 days, the functional independence (defined as mRS scores 0-2) at 90 days, proportion of patients with symptomatic intracerebral hemorrhage (sICH) and death at 90 days. We assessed the risk of bias using the Cochrane tool. Pre-specified subgroup analyses were performed by age (≤70 years or >70 years), National Institute of Health Stroke Scale (NIHSS, ≤10 or >10) and time window (4.5-9.0 h or >9.0 h).Results:Four trials involving 848 patients were eligible. The risk of bias of included trials was low. Patients in the IVT group were more likely to achieve favorable functional outcomes (45.8% vs. 36.7%; OR 1.48, 95% CI 1.12-1.96) and functional independence (63.8% vs. 55.7%; OR 1.43, 95% CI 1.08-1.90) at 90 days, but had higher risk of sICH (3.0% vs. 0.5%; OR 5.28, 95% CI 1.35-20.68) at 90 days than those in the CG. No significant difference in death at 90 days was found between the two groups (7.0% vs. 4.1%; OR 1.80; 95% CI 0.97-3.34).Conclusions:Use of IVT in patients with extended time window may improve their functional outcomes at 90 days, although IVT may induce increased risk of sICH. Care of these patients should well balance the potential benefits and harms of IVT.

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简介：AbstractPurpose:This study aimed at exploring the application of trauma time axis management in the treatment of severe trauma patients by using the Medicalsystem trauma system.Methods:We performed a retrospective cohort study involving patients with severe trauma. Patients who were admitted before the application of the Medicalsystem trauma system were divided into before system group; patients who were admitted after the application of the system were divided into after system group. Comparison was made between the two groups. For normally distributed data, means were reported along with standard deviation, and comparisons were made using the independent samples t test. Categorical data were compared using the Chi-square test. The Mann-Whitney U test was used to compare nonparametric variables.Results:There were 528 patients admitted to the study during the study period. There was no significant statistical difference in the time from the start of trauma team to arrive at the resuscitation room between the two groups. The time from arrival at hospital to endotracheal intubation, to ventilator therapy, to blood transfusion, to completion of CT scan, to completion of closed thoracic drainage, to the start of operation, as well as the length of stay in resuscitation room and hospital were significantly lower after the application of the Medicalsystem trauma system. The mortality was decreased by 8.6% in the after system group compared with that in the before system group, but there was no statistical difference.Conclusion:The Medicalsystem trauma system can optimize diagnosis and treatment process for trauma patients, and accordingly improve the treatment efficiency and shorten the treatment time. Therefore, the Medicalsystem trauma system deserves further popularization and promotion.

简介： 【摘要】译林版小学《英语》中，教材各个单元的均增设了Ticking time自我评价板块，通过多元评价，引导学生了解自己对所学主要内容的掌握情况，反思和调控自己的学习过程，体验进步与成功，认识自我，明确方向。

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简介：摘要：良好的时间观念不仅是幼儿形成良好学习、生活习惯的前提，更为幼儿的终身发展奠定了坚实基础。然而大班的幼儿时间意识较为淡薄，存在早上到园时间迟、做事拖拉、对时间以及时间相关的规则概念模糊等问题。针对这些问题，我们在大班养成系列活动中加入了时间观念的培养，通过引导幼儿在实践中更为自主地探索获得经验，感知理解时间，学习运用时间，最终成为时间的小主人，学会管理时间。

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简介：摘要：本文立足于Story time板块教学，从激发阅读兴趣、提高阅读能力、演绎阅读精彩和提升阅读品格四个方面来提升学生的阅读素养。

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简介：摘要：目的：探讨不同的翻身时间间隔对患者压力性损伤发生的影响。方法：选取在我院骨科收治入院的患者180例，随机分为Ⅰ、Ⅱ、Ⅲ、Ⅳ四组，每组患者45例，其中入组患者均卧在气垫床上，对于上述四组患者分别间隔2h、4h、8h、16h进行翻身。观察患者受

简介：【摘要】在译林版《英语》教材中，Checkout time板块是每个单元的综合检测板块。教师可以选择贴合主题的绘本，与该板块相结合，设计融听、说、读、写于一体的教学活动，充分利用绘本的育人价值，深化单元主题意义。

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简介：摘要：在双减政策的背景下，对小学英语的教学提出了更高的要求，小学英语属于基础英语教学，能够为学生以后学习英语创造条件，教师要把握好时机，充分利用好英语教材中每一环节的教学内涵，文章为教师探究小学英语中story time部分的教学提出了相关策略。