简介：目的探讨一组特殊设计镜片对周边屈光度、周边清晰视力范围和主观感受的影响。方法3例（4眼）被试者，年龄22-31岁，屈光度-2．0D，按随机顺序分别在单眼配戴普通非球面镜片、成长乐镜片、视特保大、中、小光区镜片的情况下进行周边屈光度、周边清晰视力范围测量和主观评分，主观评分包括远距和近距戴镜舒适度、清晰度和接受度。结果配戴5种镜片时，被试眼相对周边屈光度均为远视状态，远视度数随周边角度增加而增加。配戴普通非球面镜片和视特保大光区镜片时周边远视度数最大，视特保中光区镜片其次，成长乐镜片和视特保小光区镜片最小；配戴普通非球面镜片和视特保大光区镜片时的周边清晰视力范围最大，其次是视特保中光区镜片，最小的是成长乐镜片和视特保小光区镜片；远距评分为普通非球面镜片最高，视特保大光区镜片其次，然后为视特保中光区镜片，成长乐镜片及视特保小光区镜片最差；近距评分视特保大光区镜片接近普通非球面镜片，视特保中光区镜片和成长乐镜片其次，视特保小光区镜片最差。结论不同设计的中周部加光镜片对改变周边屈光度的作用存在差异，其配戴后的顺应性与镜片改变周边屈光度的程度呈负相关。

简介：随着互联网技术的发展及其与教育的有机结合，眼科教学面临新的机遇和挑战。应完善基于医疗“大数据”技术、虚拟现实技术和移动互联技术为主要内容的眼科教学方法，提升“互联网＋”背景下眼科教师的教学素养，从而促进学生自主学习、个性化学习，达到提高学习效率、改善学习效果的目的。

简介：目的研制一种实用型显微手术教学培训眼球固定台.方法利用有机玻璃、注射器、压力表等制作一种用于显微手术教学培训的眼球固定台.结果使用方便、灵活,压力稳定性强,有利于清洁,取材方便,制作简单,成本低廉.结论该固定台是一种值得推广应用的显微手术教学与培训的眼球固定台.

简介：上课是常规教学中一个很重要的环节,课堂教学的效率高低直接影响到教学质量的好坏。多媒体课件质量、多媒体与传统板书教学的融合以及多媒体教学方式好坏直接决定教学质量,笔者在对这一问题探讨和分析后,试图寻找出一套较为完整的适合于该课程的教学方式,提高学生学习兴趣,使学生掌握教学重点和难点,取得更好效果。

简介：Thekeratoprosthesis(KPro;artificialcornea)isaspecialrefractivedevicetoreplacehumancorneabyusingheterogeneousformingmaterialsfortheimplantationintothedamagedeyesinordertoobtainacertainvision.Themainproblemsofartificialcorneaarethebiocompatibilityandstabilityofthetissueparticularlyinpenetratingkeratoplasty.Thecurrentstudiesoftissue-engineeredscaffoldmaterialsthroughcomprisingcompositesofnaturalandsyntheticbiopolymerstogetherhavedevelopedanewwaytoartificialcornea.Althoughawideagreementthatthelong-termstabilityofthesedeviceswouldbegreatlyimprovedbythepresenceofcorneacells,modificationofkeratoprosthesistosupportcorneacellsremainselusive.Mostofthestudiesoncornealsubstratematerialsandsurfacemodificationofcompositeshavetriedtoimprovethegrowthandbiocompatibilityofcorneacellswhichcannotonlyreducethestimulusofheterogeneousmaterials,butalsomoreimportantlycontinuousandstablecorneacellscanpreventthedestructionofcollagenase.Thenecrosisofstromaandspontaneousextrusionofthedevice,allowformaintenanceofaprecornealtearlayer,andplaytheroleofensuringagoodopticalsurfaceandresistingbacterialinfection.Asaresult,improvementincornealcellshasbeenthemainaimofseveralrecentinvestigations;someefforthasfocusedonbiomaterialforitswellbiologicalpropertiessuchaspromotingthegrowthofcorneacells.Thepurposeofthisreviewistosummarythegrowthstatusofthecornealcellsaftertheimplantationofseveralartificialcorneas.

简介：AIM:Todescribethedesignandpreliminaryresultsofthehospitalbasedepidemiologicalstudyfordiabeticretinopathy(HBESDR),anongoingepidemiologicalstudytoestimatetheprevalenceofdiabeticretinopathy(DR)andtoelucidatetheclinical,anthropometric,biochemicalandanyotherriskfactorsassociatedwithdiabeticretinopathy.METHODS:Totally2000diabeteswillberecruitedfromtheDiabeteseyeclinicintheFirstAffiliatedHospitalofChinaMedicalUniversity.AllsubjectsunderwentbloodsugarestimationandOralGlucoseToleranceTesttodiagnosediabetes.Alldiabeteswouldundergocompletequestionnaire,acomprehensiveeyeexamination.Bloodandurinewouldbecollectedforbiochemicalinvestigations.AllfundusphotographsforanyDRwillbegraded.Participantswhoneedtreatmentwillbesenttotheophthalmicclinicandfollow-upintervalprogramforallsubjectswillbesuggested.Acomputerizeddatabaseiscreatedfortherecords.RESULTS:Todate,1174diabeteshavebeenrecruited,therewere350(29.81%)DRinalldiabetes,mostofthemwerewithmildnon-proliferativediabeticretinopathy(NPDR)(139,39.71%);71(20.29%)moderateNPDR,66(18.86%)severeNPDR,74(21.14%)proliferativediabeticretinopathy(PDR).Females,longerdurationofdiabetes,familyhistoryofdiabetesandhypertensionhadastatisticallysignificantincreaseinriskofanyDR.CONCLUSION:ThestudyisexpectedtoprovideanestimateoftheoverallprevalenceofDRandtheprevalencewithdifferentdurationofdiabetesandalsoabetterunderstandingoftheriskfactorsassociatedwithDR.

简介：在瞬息万变的信息化社会里,加强医学生创新能力的培养是适应医学发展的必要条件。本文结合眼科学的特点,初步探讨在眼科教学活动中医学生创新能力培养所存在的问题和解决方案,为提高医学生的创新能力,更好的服务临床提供帮助。

简介：AIM:Todemonstratethemorphologyandstructureofinvitroreconstructedtissue-engineeredhumancornealepithelium(TE-HCEP)withseedercellsfromanuntransfectedHCEPcellline.·METHODS:TheTE-HCEPswerereconstructedinvitrowithseedercellsfromanuntransfectedHCEPcellline,andscaffoldcarriersofdenudedamnioticmembrane(dAM)inair-liquidinterfaceculturefor3,5,7and9days,respectively.Thespecimenswereexaminedwithhematoxylin-eosin(HE)stainingofparaffin-section,immunocytochemicalstaining,scanningandtransmissionelectronmicroscopy.·RESULTS:DuringinvitroreconstructionofTE-HCEP,HCEPcellsformeda3-4,6-7and8-10layersofanHCEP-likestructureondAMsinair-liquidinterfaceculturefor3,5and7days,respectively.Butthecellsdeceasedto5-6layersandthestructureofstraifiedepitheliumbecamelooseatday9.Andthecellsmaintainedpositiveexpressionofmarkerproteins(keratin3andkeratin12),cell-junctionproteins(zonulaoccludens-1,E-cadherin,connexin43andintegrinβ1)andmembranetransportproteinofNa+-K+ATPase.TheHCEPcellsinTE-HCEPwererichinmicrovillionapicalsurfaceandestablishednumerouscell-cellandcell-dAMjunctionsatday5.·CONCLUSION:ThemorphologyandstructureofthereconstructedTE-HCEPweresimilartothoseofHCEPinvivo.TheHCEPcellsinthereconstructedTE-HCEPmaintainedthepropertiesofHCEPcells,includingabilitiesofformingintercellularandcell-extracellularmatrixjunctionsandabilitiesofperformingmembranetransportation.TheuntransfectedHCEPcellsanddAMscouldpromisinglybeusedinreconstructionHCEPequivalentforclinicalcornealepitheliumtransplantation.