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26 个结果
  • 简介:目的:观察翼状胬肉切除联合角膜缘干细胞移植及术后药物治疗翼状胬肉的临床疗效。方法:共行翼状胬肉切除联合角膜缘干细胞移植术治疗的翼状胬肉患者760例980眼。选取亚复发期的162例162眼进行观察,随机分为A,B两组,A组滴1g/L丝裂霉素C+诺氟沙星滴眼液1~3mo;B组交替滴地塞米松滴眼液、双氯芬酸钠滴眼液1~3mo。结果:A组痊愈67眼(81.7%),亚复发12眼(14.6%),复发3眼(3.7%)。B组痊愈35眼(43.8%),亚复发29眼(36.3%),复发16眼(20.0%)。A组复发率明显低于B组(P〈0.01)。结论:翼状胬肉切除联合自体角膜缘干细胞移植术,无排斥反应、安全有效、术后复发率低,术后给予滴眼液后续治疗尤为重要,更能有效地抑制和降低翼状胬肉术后的复发率,能明显提高治疗效果。

  • 标签: 角膜缘干细胞移植 药物治疗 滴眼液
  • 简介:目的:通过多焦视网膜电图(multifocalelectroretinography,mf-ERG)在中心性浆液性脉络膜视网膜病变(centralserouschorioretinopathy,CSC)治疗前后的观察,提高CSC诊断的准确性,并指导临床诊疗,评估预后。方法:设置有比较性的CSC观察组和双眼正常的对照组。观察组有31例CSC患者都是单眼发病,这些患者每只眼(包括患眼与对侧眼)在发病期与恢复期都经过眼科的系统检查,包括最佳矫正视力、眼底荧光血管造影、OCT和mf-ERG,并记录这些检查的数据。对照组有30例,与观察组年龄范围相同,同样做上述检查并记录数据。对两组数据进行对比分析。结果:在CSC发病期,mf-ERG显示患眼平均视网膜振幅密度在1环为60.54±18.20nV/degree2,比对照组(110.94±31.20nV/degree2)低45.43%(P〈0.01),在2环为38.12±10.81nV/degree2,比对照组(60.91±11.43nV/degree2)低37.42%(P〈0.05)。在恢复期,mf-ERG显示患眼平均视网膜振幅密度在1环为93.71±14.13nV/degree2,比对照组(110.94±31.20nV/degree2)低15.53%(P〈0.05);在2环为51.16±10.34nV/degree2,比对照组(60.91±11.43nV/degree2)低16.01%(P〈0.05)。另外,我们还发现,观察组31例患者中有8例对侧眼也显示出异常,平均视网膜振幅密度在1环为62.41nV/degree2,其余23例患者对侧眼未发现异常。结论:多焦视网膜电图有助于中心性浆液性脉络膜视网膜病变患者的临床治疗与随访观察,对中心性浆液性脉络膜视网膜病变患者的诊断、病情评估及预后都起着重要的作用。

  • 标签: 中心性浆液性脉络膜视网膜病变 多焦视网膜电图
  • 简介:目的观察微小切口非超声乳化白内障摘除联合折叠式人工晶状体植入术手术效果.方法抽选107例(107眼)行微小切口非超声乳化白内障摘除联合折叠式人工晶状体植入术,112例(112眼)行小切口非超声乳化白内障摘除联合硬片人工晶状体植入术,比较术后1周视力.结果术后1周视力大于0.3者分别为88.78%及66.96%.结论微小切口非超声乳化白内障摘除联合折叠式人工晶状体植入术术后1周视力优于小切口非超声乳化白内障摘除联合硬片人工晶状体植入术,术后近期(1周)效果与超声乳化近期(1周)效果相近,在缺少设备、缺少投入的基层医院值得推广使用.

  • 标签: 白内障 微小切口 折叠式人工晶状体
  • 简介:AIM:Toevaluatetheepidemiologic,anatomic,andclinicalfeaturesofopenglobeinjuriesinchildren.METHODS:Themedicalfilesofpatientsundertheageof16whohadbeenoperatedforanopenglobeinjuryatAkdenizUniversityHospital’sDepartmentofOphthalmologywereretrospectivelyevaluated.RESULTS:Atotalof90patientswereevaluatedinthisstudy.Amongthesepatients,26(28.9%)werefemaleand64(71.1%)weremale.Themeanageofthepatientswas7.7±4.2years.Themale/femaleratiowasobservedtoincreasewithincreasingage(P=0.006,P=7.48).Injuriesweremostlikelytooccurinspringandautumn(P=0.028).Thetimeintervalbetweentheinjuryandthesurgicalrepairwas9.36±27.4h.Forty(44.4%)oftheinjuriesoccurredinthehome,27(30%)occurredintheyard,and21(23.3%)happenedwhileplayinginthestreet.Themostcommoncausesofinjuryweresharpmetalobjects(P<0.001).Injurytothecorneaoccurredin47(52.2%)ofthepatients(P<0.001).Themostcommoncomplicationtooccurwascataractformation.Additionaloperationswerenecessaryfor37(41.1%)ofthepatients.Thefinalvisualacuitywascorrelatedwithboththeinitialvisualacuityofthewoundedeyepriortosurgeryandthelengthofthewound(P<0.001,r=0.502andP<0.001,r=-0.442,respectively).CONCLUSION:Openglobeinjuriesthataresufferedinchildhoodgenerallyoccureitherathome,intheyard,oronthestreet,withsharpmetalobjectsbeingthemostcommoncauseofinjury.Theinitialvisualacuityandthelengthofthewoundarethemostimportantdeterminantsofthefinalvisualacuity.

  • 标签: CHILDHOOD EPIDEMIOLOGY open globe INJURY PREVENTION
  • 简介:Choroidalneovascularization(CNV)isanuncommoncomplicationassociatedwithamacularhole.Inthiscasereportofararecondition,wepresentapathologicmyopiapatientwithaco-existentmacularholeandchoroidalneovascularmembrane.ThepatientwastreatedwithphotodynamictherapyforCNV,andthenvitreoussurgeryfortheretinaldetachmentandmacularhole.Attheendof4yearsfollow-up,hervisualacuitywasimprovedto0.1whilethemacularholeremainedopen.OpticalcoherencetomographyisausefulinspectionmethodofthediagnosisofCNVandmacularhole.

  • 标签: choroidal NEOVASCULARIZATION MACULAR HOLE PATHOLOGIC MYOPIA
  • 简介:AIM:ToIntroduceanewspecializedvisualacuitychartforamblyopicchildrenaged3-5yearsoldanditsclinicalapplications.METHODS:ThenewvisualacuitychartandnotationsweredesignedbasedonWeber-Fechnerlaw.Theoptotypeswereredagainstawhitebackgroundandwerespeciallyshapedfourbasicgeometricsymbols:circle,square,triangle,andcross.Aregulargeometricprogressionoftheoptotypesizesanddistributionwasemployedtoarrangein14lines.Theprogressionrateoftheoptotypesizebetweentwolineswas1.2589andthetestingdistancewas3m.VisualacuityscorecouldberecordedaslogMARnotationordecimalnotation.Agestratifieddiagnosticcriteriaforamblyopiaestablishedbyconsensusstatementondiagnosisofamblyopia(2011)amongmembersoftheStrabismusandPediatricOphthalmologyGroup,OphthalmologySociety,ChineseMedicalAssociation(SPOGOSCMA)wereillustratedinthenewvisualacuitychart.RESULTS:Whenassessingvisualacuityinchildrenaged3-5yearsold,thisnewvisualacuitychartthatconsistsoffoursymmetricalshapes(triangle,square,cross,andcircle)overcameaninabilitytorecognizethelettersofthealphabetanddifficultiesindesignatingthedirectionofblackabstractsymbolssuchasthetumbling’E’orLandolt’C’,whichthesubjectswerepronetoloseinterestin.Thevisualacuityscoremayberecordedindifferentnotations:decimalacuityandlogMAR.Thesetwonotationscanbeeasilyconvertedeachotherintheneweyechart.Themeasurementsofthisnewchartnotonlyshowedasignificantcorrelationandagoodconsistencywiththeinternationalstandardlogarithmicvisualacuitychart(r=0.932,P<0.01),butalsoindicatedahightest-retestreliability(89%ofretestscoreswerewithin0.1logMARunitsoftheinitialtestscore).CONCLUSION:Theresultsofthisstudysupportthevalidityandreliabilityofdistancevisualacuitymeasurementsusingtheneweyechartinchildrenaged3to5yearsoverawiderangeofvisualacuities,andtheneweyechartisgreatforearl

  • 标签: amblyopic CHILDREN Weber-Fcchner LAW INTERNATIONAL standard