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简介：Basedonthewhiteningpropertyofwavelettransformationfor1/fnoise,thispaperaddressestheproblemofdetectingdeterministicsignalsinthepresenceof1/ffractalnoise.Thetransferfunctionofwhiteningfilterisprovidedaswellastheconditionforwhitening.ThereceiverstructurebasedonKarhunen-Loeveexpansionandthedecisionrulearealsogiven.Finallyperformanceofthedetectorisanalyzed.

简介：<正>Theinitiationofthe"SilkRoadEconomicBeltandthe21st-CenturyMaritimeSilkRoad"strategy（"BeltandRoad"strategy）inthefallof2013haspromotedboththeoffshoreandmaritimedevelopmentbetweenChinaanditsneighbors.Inthebeginningof201S,theChineseGovernmentofficiallyannouncedtheimplementationofthe"BeltandRoad"strategy.Asaninternational-

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简介：疟蚊属同姓的学生中年龄是在南部的中国和东南亚洲的人的疟疾的重要向量。蚊子的phylogenetics很好没被解决，并且mitochondrial染色体(mtgenome)证明了是在进化生物学的学习的一个重要标记。在这研究，完全的mtgenome一。同姓的学生中年龄第一次被定序。它长是15395bp并且编码37基因，包括13编码蛋白质的基因(PCG)，22转移RNA(tRNAs)，二ribosomalRNA(rRNAs)和一个非编码的区域。基因组织与已知的疟蚊属mtgenomes的那些一致。mtgenome在核苷酸作文执行清楚的偏爱与一积极在斜并且一否定GC斜。所有13PCG喜欢使用codonUUA(列伊)，ATN作为开始codon但是cytochrome-oxidase子单元1(COI)并且ND5与TCG和GTG，并且TAA作为结束codon，而是COI，COII，COIII和ND4，都与不完全的T。tRNAs有典型四叶苜蓿形的立体道路交叉点结构，而是tRNA重量的单位(AGN)与已知的疟蚊属mtgenomes一致。控制区域包括保存T段并且一(TA)n段，并且在93.1%点有最高的A+T内容。phylogenetics一。与18另外的疟蚊属种类同姓的学生中年龄被最大的可能性的和贝叶斯的推理构造，基于并置的PCG序列。subgenera，Cellia和疟蚊属，和Nyssorhynchus和Kerteszia分别地有互相靠近的关系。Neomyzomyia系列的Punctulatus组和Leucosphyrus组，和Albitarsis系列的Albitarsis组被建议是monophyletic。进一步要阐明的subgenera，Cellia，疟蚊属，Nyssorhynchus和Kerteszia需要的monophyletic地位。

简介：纸为积极Markovian涉及积极观察员设计跳有部分已知的转变率的系统。由使用一个线性co积极的类型Lyapunov-Krasovskii函数，一个足够的条件被建议保证错误的随机的稳定性积极系统和积极观察员的存在，它在线性编程被计算。最后，一个例子被给表明主要结果的有效性。

简介：AbstractIntroduction:Muir-Torre syndrome is a phenotypic variant of Lynch syndrome characterized by a predisposition for the development of visceral malignant disease and sebaceous gland neoplasms, and it is caused by germline mutations in the mismatch repair genes MSH2 and MLH1.Here, we reported a patient with sebaceous neoplasm containing MLH1 c.199G>A mutation.Case presentation:The proband was a 42-year-old man who had undergone surgical resection of colorectal adenocarcinoma at 28 years. He presented with macular rashes and red papule. Histological examination of the lesion on his head revealed a sebaceoma at 37 years. Follow-up of the family history revealed that the proband’s 65-year-old mother had been highly suspected to have Lynch syndrome with colorectal cancer at 40 years of age. The proband’s daughter underwent colonoscopy because of blood in the stool at the age of 13 years, but no abnormalities were found.Discussion:We have herein reported a pathogenic missense mutation c.199G>A (p.Gly67Arg) in exon 2 of MLH1 in patients with MTS. This mutation has been reported in patients with Lynch syndrome who have no skin tumors. However, we also found that some patients with MTS had no history of any internal malignancy or skin tumor. Our data support the idea that a hiatus of many years may pass before both elements-a sebaceous neoplasm and an internal cancer-are present in a patient, thus finally allowing the diagnosis of MTS.Conclusion:A pathogenic Lynch syndrome mutation c.199G>A in exon 2 of the MLH1 gene was found in a patient with MTS who presented with a sebaceous neoplasm.

简介：内核函数在为解决线性优化问题为最初双的内部点的算法定义新搜索方向起一个重要作用。在这篇论文我们在场与最好已知的复杂性产出一个算法的新核功能为大更改、小更改的方法跳了。

简介：Thelivingmorphologyandinfraciliatureofaheterotrichousciliate,Folliculinopsisproducta(Wright,1859)Frauré-Fremiet,1936,whichwascollectedfromthenorthcoastofChina,wereinvestigatedbyinvivoobservationandprotargolimpregnationtechniques.Asanewcontribution,aredescriptionispresented:largeFolliculinopsisofgreentodarkgreenincolor,800-1500μminsize;twoperistomiallobesofapproximatelyequalsize,300-400μminlength;adoralzoneofmembranellescontainingabout1000membranelles,lyingalonglobemarginsandexhibitingtwocircleswithinbuccalcavity;50-70somatickinetiesinmid-body;macronucleusminiliform,consistingofabout20beads;loricasmooth,vase-shaped,(300-500)μm×(90-130)μminsize,with5-12spiralridgesonnecktube;marinehabitat.

简介：Thecommonapproachtofindco-regulatedgenesistoclustergenesbasedongeneexpression.However,duetothelimitedinformationpresentinanydataset,genesinthesameclustermightbeco-expressedbutnotnecessarilyco-regulated.Inthispaper,weproposetointegrateknowntranscriptionfactorbindingsiteinformationandgeneexpressiondataintoasingleclusteringscheme.Thisschemewillfindclustersofco-regulatedgenesthatarenotonlyexpressedsimilarlyunderthemeasuredconditions,butalsosharearegulatorystructurethatmayexplaintheircommonregulation.Wedemonstratetheutilityofthisapproachonamicroarraydatasetofyeastgrownunderdifferentnutrientandoxygenlimitations.Ourintegratedclusteringmethodnotonlyunravelsmanyregulatorymodulesthatareconsistentwithcurrentbiologicalknowledge,butalsoprovidesamoreprofoundunderstandingoftheunderlyingprocess.Theaddedvalueofourapproach,comparedwiththeclusteringsolelybasedongeneexpression,isitsabilitytouncoverclustersofgenesthatareinvolvedinmorespecificbiologicalprocessesandareevidentlyregulatedbyasetoftranscriptionfactors.

简介：Inthispaper,stochasticglobalexponentialstabilitycriteriafordelayedimpulsiveMarkovianjumpingreaction-diffusionCohen-Grossbergneuralnetworks(CGNNsforshort)areobtainedbyusinganovelLyapunov-Krasovskiifunctionalapproach,linearmatrixinequalities(LMIsforshort)technique,It?formula,Poincar′einequalityandHardy-Poincaréinequality,wheretheCGNNsinvolveuncertainparameters,partiallyunknownMarkoviantransitionrates,andevennonlinearp-Laplacediffusion(p>1).ItisworthmentioningthatellipsoiddomainsinRm(m≥3)canbeconsideredinnumericalsimulationsforthefirsttimeowingtothesyntheticapplicationsofPoincar′einequalityandHardy-Poincar′einequality.Moreover,thesimulationnumericalresultsshowthateventhecorollariesoftheobtainedresultsaremorefeasibleandeffectivethanthemainresultsofsomerecentrelatedliteraturesinviewofsignificantimprovementintheallowableupperboundsofdelays.