简介:Thousandsofyearsago,Britainwascoveredbythickforests,hometomanyanimalswhichnolongerliveintheUnitedKingdom.Therewerewolvesandbears,manydifferenttypesofdeerandmassivewildcattlecalledaurochs.Therewerelessthanfourmillionpeople.Theylivedinsmallvillagesprotectedbywoodenwallsfromtheanimalsoutside.
简介:假如再回到童年,我会更多地培养自己的毅力,决不因为事情艰难或麻烦而放弃不干。如果我们要光明,我们就得征服黑暗。在产生的结果方面,毅力往往可以与天才相媲美。谚语说:“能登上金字塔的生物只有两种——雄鹰与蜗牛。”假如再回到童年,我会培养自己专心致志的习惯;一旦手头有事,决不让任何东西使我分心。我
简介:Axonaldegenerationisapivotalfeatureofmanyneurodegenerativeconditionsandsubstantiallyaccountsforneurologicalmorbidity.AwidelyusedexperimentalmodeltostudythemechanismsofaxonaldegenerationisWalleriandegeneration(WD),whichoccursafteracuteaxonalinjury.Intheperipheralnervoussystem(PNS),WDischaracterizedbyswiftdismantlingandclearanceofinjuredaxonswiththeirmyelinsheaths.Thisisaprerequisiteforsuccessfulaxonalregeneration.Inthecentralnervoussystem(CNS),WDismuchslower,whichsignificantlycontributestofailedaxonalregeneration.Althoughitiswell-documentedthatSchwanncells(SCs)haveacriticalroleintheregenerativepotentialofthePNS,todatewehaveonlyscarceknowledgeastohowSCs‘sense'axonalinjuryandimmediatelyrespondtoit.Inthisregard,itremainsunknownastowhetherSCsplaytheroleofapassivebystanderoranactivedirectorduringtheexecutionofthehighlyorchestrateddisintegrationprogramofaxons.Olderreports,togetherwithmorerecentstudies,suggestthatSCsmountdynamicinjuryresponsesminutesafteraxonalinjury,longbeforeaxonalbreakdownoccurs.TheswiftSCresponsetoaxonalinjurycouldplayeitherapro-degenerativerole,oralternativelyasupportiverole,totheintegrityofdistressedaxonsthathavenotyetcommittedtodegenerate.Indeed,supportingthelatterconcept,recentfindingsinachronicPNSneurodegenerationmodelindicatethatdeactivationofakeymoleculepromotingSCinjuryresponsesexacerbatesaxonalloss.Ifthisholdstrueinabroaderspectrumofconditions,itmayprovidethegroundsforthedevelopmentofnewglia-centrictherapeuticapproachestocounteractaxonalloss.
简介:Inarecentstudy,researcherstookadultfemaleFischerratsandperformedaspinalcordtransectionontheminanattempttostudythegrowthoftransplantedearly-stageneurons.Whensuchearly-stageneuronsweretransplantedintoratssufferingfromparalysis,remarkableaxonalgrowthwasobserved.Theresultwasmanynewrelaycircuitsthatformed,whichsignificantlyimprovedfunction,
简介:AccordingtothesourcefromtheConstructionDepartmentofMinistryofEnergy,itisplannedtoaddinnationwidethisyear55mediumandlargesizedpowergeneratingsetstotaled
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简介:Nowadays,thewordglobalizationhasbecomeamostexposedwordincontextsofeconomy,cultureandpolitics.Amongthethreefields,economicglobalizationhasbeenpaidmoreattentionto.Inthisarticle,theauthorintendstodiscusstheissueofculturalglobalization.Indetail,hewantstoanalyzetheimpactsofculturalglobalizationinthemakingofcontemporaryChineseculture.First,theauthordiscussedthattheculturalglobalizationismostlyculturalwesternization.Second,heexplainedthatculturalwesternizationisnotamonstertoChineseandtheconstructionofmodernChineseculture.Thirdlyandlastly,bydiscussingsomesignificancesofwesternculture,theauthorsuggestedthosesignificancesofwesternculturearevaluabletobeabsorbedinthemakingofChineseculturegreatagain.