简介:Thecombinationofdeepwetetchingandamagneto-rheologicalfinishing(MRF)processisinvestigatedtosimultaneouslyimprovelaserdamageresistanceofafused-silicasurfaceat355nm.ThesubsequentlydepositedSiO2coatingsareresearchedtoclarifytheimpactofsubstratefinishingtechnologyonthecoatings.Itisrevealedthatadeepremovalproceedingfromthesinglesideordoublesidehadasignificantimpactonthelaser-induceddamagethreshold(LIDT)ofthefusedsilica,especiallyfortherearsurface.Afterthedeepetching,theMRFprocessthatfolloweddoesnotactuallyincreasetheLIDT,butitdoesamelioratethesurfacequalitieswithoutadditionalLIDTdegradation.Thecombinationguaranteeboththeintegrityofthesurface’sfinishandthelaserdamageresistanceofthefusedsilicaandsubsequentSiO2coatings.
简介:TheCa_2SiO_4:Dy~(3+)phosphorwassynthesizedbythehightemperaturesolid-statereactionmethodinair.TheemissionspectrumofCa_2SiO_4:Dy~(3+)phosphorshowsseveralbandsat486,575,and665nmunderthe365-nmexcitation.TheeffectsofLi~+,Na~+,andK~+ontheemissionspectrumofCa_2SiO_4:Dy~(3+)phosphorwerestudied,TheresultsshowthattheemissionspectrumintensityisgreatlyinfluencedbyLi~+,Na~+,andK~+.Thechargecompensationconcentrationcorrespondingtothemaximumemissionintensityisdifferentwithdifferentchargecompensations.
简介:Higher-bandself-trappingandoscillation(rotation)ofnonlinearquadruplebeamsintwo-dimensional(2D)squarephotoniclatticesarenumericallydemonstrated.Underappropriateconditionsofnonlinearity,aquadruple-likebeamcanself-trapintolocalizedmodesthatresideinthesecondBraggreflectiongapthroughsingle-siteexcitation.Bychangingtheinitialorientationoftheincidentquadruplebeamrelatedtothelattices,periodicoscillationsofthelocalizedquadruplemodemaybeobtained.Thelocalizedquadruplestatebecomesarotatingdoublychargedopticalvortex(DCV)duringrotationandshouldundergocharge-flippingwhentherotatingdirectionisreversed.
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简介:基于菰黑粉菌全基因组测序结果及其酵母型和菌丝型转录组差异化表达数据库,结合RACE技术克隆获得一个长度为7625bp的基因,其中编码序列为5874bp,无内含子.结构及聚类分析结果表明该基因编码的MAPKKK蛋白激酶,属于Hogl信号途径,与大麦坚黑粉菌中的Ssk2亲缘关系最近.表达分析结果显示:UeSsk2在菌丝诱导形成过程中持续上调表达,而在生长受到抑制的菌丝细胞中其表达无显著变化或受到抑制,表明UeSsk2与菌丝形成具有相关性.同时,经生物传感器进行的蛋白互作检测结果表明,UeSsk2与前期发现的UeMkkl不存在蛋白互作关系,表明该蛋白参与其他MAPK途径来影响菌丝形成及生长.
简介:碱性成纤维细胞生长因子2(fibroblastgrowthfactor2,FGF2)是一类功能多样的多肽,可由视网膜的多种细胞分泌产生。随着对视网膜血管性疾病的研究深入,FGF2在其中的作用也得到广泛重视。FGF2可与血管内皮生长因子(vascularendothelialgrowthfactor,VEGF)、肿瘤坏死因子-α(tumornecrosisfactor-α,TNF-α)等细胞因子相互作用,通过发挥促血管生成作用、促炎作用以及一定的神经保护作用而参与视网膜血管性疾病的发生与发展。此外,FGF2的表达上调很可能是部分患者使用抗VEGF治疗效果不显著的重要因素。本文就FGF2的分子特征、分子作用机制及FGF2与视网膜血管性疾病的相关性进行总结,旨在为FGF2作为视网膜血管性疾病的治疗靶点提供理论依据。