简介:IncreasingICdensitiesnecessitatediagnosismethodologieswithenhanceddefectlocatingcapabilities.YetthecomputationaleffortexpendedinextractingdiagnosticinformationandthestringentstoragerequirementsconstitutemajorconcernsduetothetremendousnumberoffaultsintypicalICs.Inthispaper,weproposeanRT-leveldiagnosismethodologycapableofrespondingtothesechallenges.Intheproposedscheme,diagnosticinformationiscomputedonagroupedfaulteffectbasis,enhancingboththestorageandthecomputationalaspects.Thefaulteffectgroupingcriteriaareidentifiedbasedonamodulestructureanalysis,improvingthepropagationabilityofthediagnosticinformationthroughRTmodules.Experimentalresultsshowthattheproposedmethodologyprovidessuperiorspeed-upsandsignificantdiagnosticinformationcompressionatnosacrificeindiagnosticresolution,comparedtotheexistinggate-leveldiagnosisapproaches.
简介:Traumatichematomaofposteriorfossa(THPF)isaspecialkindofcraniocerebralinjurywithitsowncharacteristicsinclinicalmanifestations,diagnosisandtreatment.Ingeneral,theprognosisofTHPFispoor.Withoutearlydiagnosisandprompttreatment,theoutcomewouldbeverypoor,withhighoccurrenceofmorbidityandmortality.Sincetheavailabilityofcomputedtomography(CT)in1983,wehavereceivedandsuccessfullytreated44patientswithTHPFuntilNovember2000.
简介:ObjectivesToevalu-atetheoutcomeofdiagnosisandsurgicaltreatmentforcortriatrium(CTA)in6patientsseenbetween1994and2002.Methods6patientsranginginagefrom5monthsto25yearswereobserved.Allofthemhadothercardiovasculardefects,andpresentedwithdyspnea,palpitations(andlowweightgrowingonlyintheinfants).Preopreativetwodimensionalechocardiogra-phyhaddemonstratedanabnormalseptumintheleftatriumandothercoexistentanomalies.In3ofthemthemembranewasobstructedbetweentheleftatrialaccessorychamberandtheleftatrium.Thecommunicationwereatrialseptaldefect(ASD)indirectly;Theclinicalfindingswereduetothepulmonaryhypervas-cularity.Onlyonecasehadafenestrationintheseptumwithasmallpatentforamenovale(FO)directly,andtheclinicalfindingswereduetotheobstructiontoflowthroughthemembraneintheleftatrium,producingvenocapilarpulmonaryhypertension.TwoofthemhadASDandfenestrationontheseptum.Theot
简介:SupersonicMolecularBeamInjection(SMBI)isanewfuellingmethodforTokamaksandhasrecentlybeenimprovedtoenhancethefluxofthebeamandtomakeasurveyoftheclustereffectwithinthebeam.Thereareaseriesofnewphenmnena,whichimplicatetheinteractionofthebeam(includingclusters)withthetoroidalplasmaofHiL-1MTokamak.TheHαsignalsfromtheedgeshowaregularvariationaroundthetorus.Aroundtheinjectionport,theedgeHαsignalsarepositiverectangularwave,whichisconsistentwiththatoftheinjectionbeampulses.Theedgeelectrontemperature,measuredwithmovableLangmuirprobes,decreasesbyanorderofmagnitudeandthedensityincreasesbyanorderofmagnitude.Hαemissionatthebeaminjectionport,measuredwithCCDcameraatanangleof13.4degreestotheSMBIline,showsmanyseparatepeakswithinthecontourplot.Thesepeaksmayshowthestrongemissionproducedbytheinteractionofthehydrogenclusterswiththeplasma.Hydrogenclustersmaybeproducedinthebeamaccordingtotheempiricalscaling(Hagena)lawofclusteringonset,heredisthenozzlediameterinμm,P0thestaguationpressureinmbar,T0thesourcetenperatureinK,andkisaconstantrelatedtothegasspecies.IfΓ*>100,clusterswillbeformed.InpresentexperimentΓ*isabout127.
简介:AbstractHarlequin ichthyosis is a severe autosomal recessive skin disorder. Most deaths occur within the first few days after birth, and the survivors still have severe chronic skin disease throughout their lives. Almost all cases were associated with a pathogenic variant of adenosine triphosphate binding cassette transporter, subfamily A, member 12 (ABCA12) gene. We described a case of HI diagnosed by ultrasound examination during the second-trimester and genetic diagnosis reveal two novel heterozygous ABCA12 mutations c.2563-2570delinsGGCAATT, p.(Leu855Glyfs*13), and c.6116delT, p.(Met2039Argfs*8) by the next-generation DNA sequencing, which further enriched our understanding of the pathogenic variation of ABCA12 gene.
简介:Objectives:Toevaluateoutcomesintreatingcarcinomaofexternalauditorycanal(EAC)andtoanalysisfactorswhicheffecttheprognosisofthisdisease.Methods:Aretrospectivelyreviewof16patientstreatedforcarcinomaofEACatourdepartmentbetweenApril2000andApril2014wasconducted.Allpatientsunderwentsurgicaltreatmentandthediagnosisconfirmedbypathologicalexamination.Results:Therewereadenoidcysticcarcinoma(ACC)in8patients,squamouscellcarcinoma(SCC)in5patients,adenocarcinoma(AC)in2patients,andverrucouscarcinoma(VC)in1patient.ThetumorswereclassifiedasStageIin4cases,StageIIin2cases,StageIIIin3cases,andStageⅣin7cases.Fivepatientsunderwentextensivetumorresection(ETR),2patientsunderwentlateraltemporalboneresection(LTBR),5patientsunderwentmodifiedLTBR,2patientsunderwentsubtotaltemporalboneresection(STBR),and2patientsunderwentonlyopenbiopsy.Besides,adjunctiveprocedures,includingneckdissection,parotidectomyandpinnaresectionwereperformedwhenindicated.Tenpatientsreceivedpostoperativeradiotherapy.Bytheendoffollowup,twopatientshaddiedoftheirdisease,2losttofollowup,2survivedwiththedisease,andtherestsurviveddisease-free.Themedianfollow-upperiodwas24months.Conclusion:CompletetumorresectionappearstobeaneffectivetreatmentforcarcinomaoftheEAC.PatientswithSCCseemtohaveworseprognosisthanthosewithACC.Radiationtherapyseemslesseffectiveforihediseasethansurgicaltreatment.
简介:无
简介:ObjectiveToretrospectivelystudyclinicalfeaturesanddiagnosticimagingofvasculogeneicpulsatiletin-nitus,andthefeasibilityandefficacyoftransvascularinterventionaltreatmentforthiscondition.MethodsDatafrom82casesofarterialorvenouspulsatiletinnituswerereviewed.DSAcharacteristicsandpossiblepathophysiologicalmechanismsofpulsatiletinnitusinthesecaseswerestudied.Diagnosesinthisgroupin-cludedintracranialarterovenousfistula(AVF)(n=3),spontaneousskullbaseduralAVF(n=16),traumaticca-rotid-cavernoussinusfistula(n=5),subclavianarterystenosis(n=2),internalcarotidarterystenosis(n=3),in-tracranialarterialstenosis(n=1),kinkedand/orelongatedvertebrobasilarartery(n=2),venoussinusdivertic-ulum(n=2),venoussinusstenosisonthedominantdrainageside(n=46)andoccipitalsinusstenosis(n=2).Treatmentsincludedembolizationandstentingusingcoils,NBCAglue,Baltballoons,self-expansionstentsandintracranialmicro-stentsviaeitherthefemoralarteryorfemoralvein.ResultsProceduresweresuc-cessfulinallcaseswithnosurgery-relatedcomplications.Tinnitusdisappearedwithin2daysafterthepro-cedureinallcases.Followupdurationwas5-36months.Recurrenceoccurredin4casesofarterialtinnituswithin3monthsfollowingtheinitialprocedure,whichimprovedafterrevisionembolizationorsymptommanagement.Therewasnorecurrenceinvenoustinnituscasesfollowingstentplasticorstent-coilingembo-lizationtreatments.ConclusionsEndovascularinterventionprovidesanewapproachtothediagnosisandtreatmentofintractablepulsatiletinnitus.Itisalsoeffectiveindifferentiatingandstudyingothertypesoftinnitus.
简介:Objective:Toimprovethediagnosisandtreatmentofseverecerebralfatembolism(SCFE).Methods:ThedataofninepatientswithSCFEwereretrospectivelyanalyzed.Themanifestationsofthecentralnervesystem,respiratorysystemandhemorrhagewererecorded,atthesametime,accessoryexaminationincludingarterialoxygen,fatmacroglobulesinvenousbloodandimageexaminationwasadapted.Thepatientsweretreatedwithexopexy,pharmocotherapyandoxygentherapy.Results:Twooftheninepatientsdiedofseverecomplications,theothersevenrecoveredwithoutseveresequela.Conclusions:GurdstandardshouldbeimprovedforearlydiagnosisofSCFE.Ifsverecomplicationscanbeprevented,patientswhoreceiveearlytreatmentwillhavefavourableprognosis.
简介:概括波浪活动密度,被定义为三维的涡度向量不安和一般潜在的温度不安的坡度的生产的绝对值,被介绍,它的波浪活动法律在笛卡儿的坐标被导出。在agoestrophic和nonhydrostatic构造了动态框架,概括波浪活动法律可能是适用的诊断导致重降雨的mesoscale天气系统。概括波浪活动密度和波浪活动流动分叉与客观分析数据被计算在重降雨的区域上调查波浪活动的字符。为与重降雨联系的骚乱负责的主要动态过程也被分析。概括波浪活动密度密切被相关到观察6-h,这被显示出积聚的降雨。这显示波浪活动或骚乱是明显的在上正面并且乍见陆地台风在中间、更低的对流层的重降雨的区域。为乍见陆地台风雨线,概括波浪活动流动分叉的部分,表示在基本状态的气旋的发行量之间的相互作用乍见陆地,台风和mesoscale飘动,是为概括波浪活动的进化负责的主要动态过程密度。
简介:AbstractAcute pancreatitis (AP) is a common acute abdominal condition of the digestive system. In recent years, treatment concepts, methods, and strategies for the diagnosis of AP have advanced, and this has played an important role in promoting the standardization of AP diagnosis and treatment and improving the treatment quality of AP patients. On the basis of previous guidelines and expert consensus, this guideline adopts an evidence-based, problem-based expression; synthesizes important clinical research data at home and abroad in the most recent 5 years; and forms 29 recommendations through multidisciplinary expert discussion, including diagnosis, treatment, and follow-up. It is expected to provide evidence support for the treatment of AP in the clinical setting in China.
简介:AbstractThe incidence of pancreatic cancer has been rising worldwide, and its clinical diagnosis and treatment remain a great challenge. To present the update and improvements in the clinical diagnosis and treatment of pancreatic cancer in recent years, Chinese Pancreatic Association, the Chinese Society of Surgery, Chinese Medical Association revised the Guidelines for the Diagnosis and Treatment of Pancreatic Cancer in China (2014) after reviewing evidence-based and problem-oriented literature published during 2015-2021, mainly focusing on highlight issues regarding diagnosis and surgical treatment of pancreatic cancer, conversion strategies for locally advanced pancreatic cancer, treatment of pancreatic cancer with oligo metastasis, adjuvant and neoadjuvant therapy, standardized processing of surgical specimens and evaluation of surgical margin status, systemic treatment for unresectable pancreatic cancer, genetic testing, as well as postoperative follow up of patients with pancreatic cancer. Forty recommendation items were finally proposed based on the above issues, and the quality of evidence and strength of recommendations were graded using the Grades of Recommendation, Assessment, Development, and Evaluation system. This guideline aims to standardize the clinical diagnosis and therapy, especially surgical treatment of pancreatic cancer in China, and further improve the prognosis of patients with pancreatic cancer.