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简介：AIM:Toinvestigateandcomparethecytopathologicalandclinicaleffectsofamnioticmembranetransplantation(AMT)andoralmucosalmembranetransplantation(OMMT)insocketcontraction.METHODS:Twelvepatientswhocouldnotbefittedwithocularprosthesisduetosocketcontracturewereincludedinthisstudy.SevenpatientsunderwentAMTand5patientsunderwentOMMT.Thirteenpatientswhohadhealthysocketswereincludedascontrolgroup.Depthofinferiorfornix,degreeofinflammation,extentofthesocketcontractureandsocketvolumeweremeasuredinthepreoperativeperiodandatsixthandtwelfthweekspostoperatively.Impressioncytologyofconjunctivalfornicesandteartransforminggrowthfactorbeta-1(TGFβ1)levelsweredetermined.RESULTS:IntheAMTgroup,socketvolumeandlowerfornixdepthvaluesweresignificantlyhigher(P=0.030andP=0.004respectively)andinflammationlevelsandimpressioncytologystages(P=0.037andP=0.022respectively)weresignificantlylowerinpostoperativeperiodcomparedtopreoperativeperiod.IntheOMMTgroup,nostatisticaldifferenceswerefoundintermsofclinicalparameters,inflammationlevelsandimpressioncytologystagesofpreoperativeversuspostoperativevalues.PreoperativetearTGFβ1levelswerehigherinAMTandOMMTgroupscomparedtothecontrolgroup(25.5ng/mL,26.3ng/mLand21.7ng/mLrespectively).DecreasedtearTGFβ1levelswereobservedinboththeAMTandOMMTgroupspostoperatively(mediandecreasevalue=2.1ng/mLand2.7ng/mLrespectively).CONCLUSION:AMTisassociatedwithpostoperativeimprovementininferiorfornixdepth,socketvolume,inflammationandimpressioncytologylevelsandmaybeamoreproperalternativemethodthanOMMTinthemanagementofsocketcontracture.

简介：AIM:Toevaluatetheeffectofreleasingtheorbicularisretainingligament(ORL)complexoftheteartroughcombinedwiththetransconjunctivalblepharoplastyinthesurgicalmanagementofteartroughdeformitycomparedwiththeeffectofblepharoplastyalone.METHODS:Aprospective,randomized(byclosedenvelopetechnique),controlledsurgicaltrialwhichincluded50patients(100eyes)withbilateralvisibleteartroughdeformityandlowereyelidfatbulging,wasdividedintotwogroupswhere25patients(50eyes)hadteartrough-ORLreleasewithblepharoplastyand25patients(50eyes)didn’t.Qualitativeandquantitativeassessmentsofteartroughdeformityweredoneat6mopostoperatively,achievinggrade0or1ofBarton’sclassificationwasconsideredasuccess.Standardizedphotographicdocumentationofeachpatientwasdonepreandpostoperatively,alsoassessmentofthepatients’satisfactionpostoperativelywasdoneandrankedasexcellent,verygood,goodorfair.RESULTS:Therewasstatisticallysignificantdifferencebetweenthetwogroupsintheoverallaestheticresultspostoperativelyregardingthequalitativeandquantitativeanalysisoftheteartroughdeformity,wherepatientswhohadteartrough-ORLcomplexreleasehadmoresuccessfuloutcomesthanthoseofthesecondgroup.CONCLUSION:ORLreleaseshouldbedoneinpatientswithteartroughdeformityinordertoreleasethetetheringeffectofthisligamentwhichcausestheprominenceofthenasojugalgroove.

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