简介:Retinoblastoma(RB)isthemostcommonintraocularcancerofinfancyandchildhood.ThiscancerisinitiatedbymutationonRB1,thetumorsuppressorgenethatisresponsiblefortheregulationofbothcellcycleandgnomestabilityinretinalcells.PatientswithaconstitutionalmutationonRB1canbeinherited.RBoccursapproximately1inevery15000-20000livebirths.Theworldwidemortalityforthiscancerisabout5%-11%.However,thisraterisestoabout40%-70%indevelopingcountriesduetoadelayindiagnosis.Awidevarietyofoptionsareavailableforthetreatment,butoftenacombinationoftherapiesisadoptedtooptimizeindividualizedcare.
简介:Voiding机能障碍例如冲动频率症候群,主张不能自制,压力不能自制和unobstructive尿保留,对pharmacotherapy经常倔强。电的neuromodulation证明了为这些状况有益。作为电的neuromodulation的一治疗,Electroacupuncturepudendal神经刺激(杀虫剂的一种)为voiding机能障碍是有益的。杀虫剂的一种的表演和申请将在这篇文章被介绍。
简介:ApplyingLagrange–Germain'stheoryofelasticthinplatesandHamiltonianformulation,thedynamicsofcantileverplatesandtheproblemofitsvibrationcontrolarestudied,andageneralsolutionisfinallygiven.BasedonHamiltonianandLagrangiandensityfunction,wecanobtaintheflexuralwaveequationoftheplateandtherelationshipbetweenthetransverseandthelongitudinaleigenvalues.Basedoneigenfunctionexpansion,dispersionequationsofpropagationmodeofcantileverplatesarededuced.Bysatisfyingtheboundaryconditionsofcantileverplates,thenaturalfrequenciesofthecantileverplatestructurecanbegiven.Then,analyticsolutionoftheprobleminplatestructureisobtained.Anhybridwave/modecontrolapproach,whichisbasedonbothindependentmodalspacecontrolandwavecontrolmethods,isdescribedandadoptedtoanalyzetheactivevibrationcontrolofcantileverplates.Thelow-order(controlledbymodalcontrol)andthehigh-order(controlledbywavecontrol)frequencyresponseofplatesarebothimproved.Thecontrolspilloverisavoidedandtherobustnessofthesystemisalsoimproved.Finally,simulationresultsareanalyzedanddiscussed.
简介:ThispaperbrieflyintroducestheSeismotectonicMapofXinjianganditsneighborhoodinthescaleof1∶2500000.Themapisamended,supplementedandexpandedbasedofthenewlycompiledSeismotectonicMapofXinjianginscale1∶1000000.ThebasemapofthisseismotectonicmapisthegeologicmapofwesternChinaanditsneighborhoodcompiledbyLiTingdong.Theabundantnewmaterialsfromrelatedresearch,referentialliteraturesandtheanalysesonremotesensingdatawereusedinthecompilingwork.Adatabaseandrelevantdocumentsarebuiltfornearly300activefaultsand150activefolds.Thebasicinformationofthemajoractivefaults,especiallythoseneartheborderareasinthismapareintroducedinthispaper.
简介:Thetransportationindustryisanessentialsectorforcarbonemissionsmitigation.ThispaperfirstlyusedtheLMDI(LogarithmicMeanDivisiaIndex)decompositionmethodtoestablishfactorsdecompositionmodelonChina’stransportationcarbonemission.Then,aquantitativeanalysiswasperformedtostudythefactorsinfluencingChina’stransportationcarbonemissionsfrom1991to2008,whichareidentifiedastransportationenergyefficiency,transportationstructureandtransportationdevelopment.Theresultsshowedthat:(1)Theimpactoftransportationdevelopmentontransportationcarbonemissionsshowedpullingfunction.Itscontributionvaluetocarbonemissionsremainedathighgrowthsince1991andshowedanexponentialgrowthtrend.(2)Theimpactoftransportationstructureontransportationcarbonemissionsshowedpromotingfunctioningeneral,butitsroleinpromotingcarbonemissionsdecreasedyearbyyear.Andwiththecontinuousoptimizationoftransportationstructure,thepromotingeffectdecreasedgraduallyandshowedtheinversed"U"trend.(3)Theimpactoftransportationenergyefficiencyontransportationcarbonemissionsshowedafunctionofinhibitionbeforepulling.Inordertopredictthepotentialofcarbonemissionreduction,threescenarioswereset.Analysisofthescenariosshowedthatifgreaterintensityemissionreductionmeasuresaretaken,thecarbonemissionswillreduceby31.01milliontonsby2015andby48.81milliontonsby2020.
简介:Mileage-basedpricinginsurance,suchasPAYD,isknownasthe'greeninsurance'becauseitislow-carbonandenvironmentallyeffective,whichisthebiggestinnovationintheglobalautoinsuranceindustryseeninthepastdecade.Startingfromtheperspectiveofeconomicexternalities,vehiclenegativeexternalitiesinChinaaredescribed.Inordertointroducemileage-basedpricinginsurancetotheChineseinsuranceindustry,thispaperreviewsthecurrentpracticeofPAYDinsuranceanditsimpactsontransportexternalities,includingairpollution,climatechange,energydependency,congestion,accidents,andothers.Finally,enlightenmentandpolicysuggestionsareproposed,inthehopeofbetterpromotingthelow-carboneconomydevelopmentoverthewholeofChina.
简介:Asatypicalcleanandrenewableenergy,windpowerisbecomingmoreandmorewidelyusedinelectricalindustry.However,itscharacteristicsofrandomandintermittenthavebroughtseriousproblemstothepowersystem,suchasvoltagefluctuationandinsufficientreactivepower.BasedontheK-meansclusteringalgorithm,thispaperclassifiesthedoubly-fedinductiongenerators(DFIG)accordingtotheoperationofpropellerpitchanglecontrol.Atthesametime,toobtaintheoptimalparameter,advancedparticleswarmoptimization(PSO)isused.ThenthedynamicmodelofDFIGunderthenetworkfaultconditionisbuilt.Whatismore,therolethatcrowbarcircuitplaysinlowvoltageridethrough(LVRT)isdiscussed.Finally,simulationsinDigSILENTverifythemodel.
简介:基于中国908工程的最近的海底的地形学数据(中国近海海洋的环境全面调查和评价),我们分析了一般中国近海影响它的发展的海底的地形学的特征和因素。离开中国的海岸的海底的地形学跟随陆地地形学的NW-SE趋势。海底的地形学的坡度与大约0.8%的一个平均坡度从0.2%~1.6%。深度轮廓与海岸变主要平行,并且在河口区域伸出到海。海底的地形学被地质的结构统治,它证明二的典型特征高举并且从北方的二个沉淀事件到向南。与不同沉积环境和复杂水动力学条件相结合的地质的结构生产了能被三种类型描绘的地形学:沉积的盆,压缩高举,和转变形式。在沉积的盆和压缩高举区域,地形学的波动是小的,沉积是有细密纹理的,并且水流流动在一个单个方向,导致有沉积平原的海湾并且在水下累积倾斜,它具有一样的构造起源。转变类型地形学被强壮的波动和混合尺寸沉积描绘粒子,平台和沿海的陡坡和架平原和侵蚀免职地形近海。这是不完全的差错块开发的结果并且重复违反。在免职改革区域(转变形式类型),地形学有强壮的波动,沉积是粗糙的,潮汐的沙山脉在源自陆地供应的河口和集中地区是开发得好的,并且Holocene沉积是厚的,由潮,河流量,和水流转变了。
简介:Bonedefectisoneofthemostcommondiseasesinclinic.Existingtherapeuticapproacheshaveencounteredmanyproblems,suchaslackofautogenousallogeneicboneandimmunologicalrejectiontoallogeneicimplant.Synthetichydroxyapatite(HA)providedsolutionsforbonerepair,sincetheHAisthemaininorganiccomponentofanimals'bone.AlthoughHAhasgoodbiocompatibility,butonlythelimitedosteogeniccapability,whichisofsignificanceformodernbonerepairmaterials.Siisanessentialtraceelementinbonetissue,andithasbeendemonstratedtobeabletopromoteboneformation.Therefore,silicate-dopedhydroxyapatite(Si-HA)mayserveasapromisingmaterialforbonerepair,andpromoteboneregenerationintherepair.ThecurrentreviewdiscussesdevelopmentofSi-HA,focusingonitspreparationandcharacterization,invitroandinvivoevaluationsofthematerial,positiveeffectofSi-HAonpromotingboneformationinclinicalapplications,andmolecularmechanisminvestigationofsuchpromotiveeffect.
简介:1.Introduction*SincethefirsttimeEasterIslandwasexplored,scholarshavebeenarguingandspeculatingaboutthedateofthenatives’arrival,thenatureandpurposeofthelargerstatues,itsactualnumberofinhabitants,thereasonsfortheprogressivedeforestationoftheisland,etc.Allofthishasreceivedvariousexplanationswhichareconsideredinfluentialfactorsindeterminingsocialandculturalchangesinthelivesoftheislanders(aquestiontobesurveyedinthelastsectionofthisarticle.)However,thelackofsufficientdatamakesitdifficulttoreachtoadefinitiveconclusion;thebestthatwecanhopeforistogivereasonableandtemptativehypotheses.
简介:UE-Bézier(unifiedandextendedBézier)basisistheunifiedformofBézier-likebases,includingpolynomialBézierbasis,trigonometricpolynomialandhyperbolicpolynomialBézierbasis.SimilartotheoriginalBézier-likebases,UE-Bézierbasisfunctionsarenotorthogonal.Inthispaper,agroupoforthogonalbasisisconstructedbasedonUE-Bézierbasis.ThetransformationmatricesbetweenUE-Bézierbasisandtheproposedorthogonalbasisarealsosolved.