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500 个结果
  • 简介:甲醇摘录ofStellerachamaejasmeL被antitumor为antitumor活动估计对鼠科的白血病P388invivo的活跃生物鉴定。摘录的bioassay-directcd分离供应了七diterpene混合物(stellerarin,stelleramacrin,gnidimacrin,pimelea因素P2,subtoxin,huratoxin,simplexin)并且二biflavanone混合物(neochemae茉莉属A和B)。在他们之中,gnidimacrin,stellerarin和stelleramacrin(新奇混合物)被发现对P388,L1210和K562invivoandinvitro有高antitumor和细胞毒素的活动。结果建议diterpene混合物是有势力antitumorprinciplesofStellerachamaejasmeL。

  • 标签: ANTITUMOR AGENTS Stellerarin Stelleramacrin Gnidimacrin Pimelea
  • 简介:试图以便识别HPTLC侧面(简历标记),在种类水平,为粗略的药的鉴定和证实,HPTLC分离在AervalanataL的不同部分上被开始。从南方印度。屏蔽的方法初步的phytochemical被Harborne的方法做。HPTLC研究被执行跟随Harborne和瓦格纳等方法。乙醇acetate-ethanol-water(8:2:1.2)为glycosides作为活动阶段被采用。结果A的茎,叶子,根,花和种子的methanolic摘录。lanata与范围0.02~0.86与23不同Rf价值显示出glycosides的23种不同类型的存在。当时,在glycoside的一般的更高的度,差异在植物的部分被观察了与繁殖部分相比。glycosides的最大的数字(12)在茎(9)跟随的根被观察了。礼品的结果学习的结论补充了拥有几的学习植物的民俗的用法知道并且有简历活动的未知bioactive混合物。由孤立并且识别这些bioactive混合物,新药能被提出治疗各种各样的疾病。

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  • 简介:从宁夏枸杞(LiciumbarbarumL.)的果实(枸杞子)中分离得到13个化合物,经光谱等方法鉴定其结构为8个长链脂肪酸(1~8),对羟基桂皮酸(pcoumaricacid,9),胡萝卜甙(daucosterol,10),β谷甾醇(βsitosterol,11),甜菜碱(betaine,12),莨菪亭(scopoletin,13)。其中化合物1~10为首次从枸杞子中得到

  • 标签: 枸杞子 化学成分
  • 简介:Defenceproteinsareakindofchemicaldefencecompounds.Theyplayakeyroleinplantrestrainingbioticandabioticharm.Toilluminateactivitiesofsomedefenseproteinsassociatedwithageorplantfamilyoflarch,thelarchneedleswerecollectedfromtwodifferentfamiliesofKoreanlarch,Larixolgensisandahybridlarch,L.kaempferi×L.gmelinii,respectively,andthentheactivitiesofdefenceproteinsinthoseweretestedusingaUVspectrophotometry.Theresultsshowedthattheactivitiesofprotectiveenzymesatthe16-/17-and19-year-agegroupswerehigherthanthoseattheotheragegroupsinthebothlarchspecies.Whiletheactivitiesofpolyphenoloxidase(PPO)atthe16-/17-year-agegroupandphenylalanineammonia-lyase(PAL)andproteaseinhibitorsatthe19-year-agegroupwerethehighestamongallagegroups.Then,comparedwithL.olgensis,thehybridlarchhadsignificanteffectsontheactivitiesofprotectiveenzymes.TheeffectsofplantfamilyontheactivitiesofPALandchymotrypsininhibitorweresignificantlydifferent,andthenthoseontheactivitiesofPPOwerenotsignificantlydifferent.TheeffectsofthetwofamiliesinL.olgensisontheactivitiesoftrypsininhibitor(TI)weresignificantlydifferent,whilethoseinthehybridlarchontheactivitiesofTIwerecontrary.Toconclusionsshowedthatthedifferentageandplantfamilysignificantlyaffectedtheactivitiesofdefenceproteinsintheneedlesoftwolarchspecies,andthenenhancedthelarchresistancetopests.Thesecouldplayakeyfunctioninforestrytreegeneticimprovementandmanagementinfuture.

  • 标签: 日本落叶松 防御蛋白 植物种类 年龄组 松针叶 胰凝乳蛋白酶抑制剂
  • 简介:ChinahasagreatresourceofCannabis.ResearchonthetaxonomyandmorphologyofChineseCannabishasbeencarriedout,butsofarnomoleculargeneticresearchhasbeenpublished.RandomamplifiedpolymorphicDNA(RAPD)isasuitabletechniqueformoleculargeneticresearchonCannabis.Intillsexperiment,usingCannabisherbariumspecimensasasourceofgeneticmaterials,thecorrelativeconditionsofthePolymerasechainreaction(PCR),(i.e.,gradientdensityofMg^2+,dNTPs,TaqDNApolymerase,annealtemperature,annealtimeandreactioncycles)wereexaminedseparately.AneffectiveprocedurefortheRAPDanalysisofCannabiswasobtained.

  • 标签: 大麻 RAPD 标本 麻药
  • 简介:MultiplicationofElaeagnusangustifoliaL.wasexaminedinvitrosuccessivelyfromasingleshootunderthespecifiedconditionofdifferentmedia,plantgrowthregulators,pHvalueandsucroseconcentration.ItwasshowedthatMMS1wasthemostsuitablemediumonshootmultiplicationamong5mediaconcerned;BAPwasthemosteffectiveoneamongallthecytokinininvolved,BAP,KN,TDZandZT;theexpluntofthetophalf-partfromashootproducedmorenewshootsthanthatofthefoothalf-partdid;morenewshoots(>2cm)wereproducedunder3%sucrosebetweentheconcentrationswithtophalf-partexplants;shootscouldgrowwellbetweenpH4.4andpH7.0,andthebiggestnumberofshootswasproducedinpH5.6,whileinpH5.8themaximumrootingrateappeared.Asaresult,thecombinationof0.5μMBAPand0.1μMIBAonMMS1mediuminducedthemaximumshootmultiplication.Thenumberofshootamplified3timesin1month,and3^12shoots(>2cm)mightbetheoreticallymultipliedannuallyfromasingleshoot.

  • 标签: 嫩芽 组织培养 培养基 激素 吲哚-3-丁酸 激动素
  • 简介:摘要目的探讨观察阿德福韦酯(ADV)联合拉米夫啶(LAM)治疗LAM耐药慢性乙型肝炎(CHB)患者的临床疗效及安全性。方法采用随机对照的方法。将76例拉米夫啶耐药的CHB患者平均随机分为治疗组与对照组,每组各38例。治疗组服用拉米夫啶100mg/d+阿德福韦酯10mg/d,连用96周。在治疗12周、48周、96周时观察两组患者血清HBV-DNA转阴,HBeAg转阴,HBeAg转换,ALT复常及治疗96周时阿德福韦酯耐药情况。结果治疗96周时治疗组HBV-DNA转阴率。治疗过程中未发现严重不良反应。结论ADV+LAM治疗拉米夫啶耐药的CHB患者在病毒学、血清学及生化学方面取得较好疗效,且耐药率低,安全性好。

  • 标签: 肝炎 乙型 慢性 抗药性 拉米夫啶 阿德福韦酯
  • 简介:Twopotexperimentswithacompletelyrandomdesignand4replicationswereperformedinagreenhousetoexaminetheresponsedifferenceof17cultivarsofpakchoi(BrassicachinensisL.)growninaCu-spikedandacleansoiltoCu.relativelytolerant.Whenthe17cultivarsofpakchoigrewincleangardensoil,theCuconcentrationsintheabovegroundpartwerepositivelycorrelated(r=0.6693)withtheirrootCuconcentrations.However,whentheygrewintheCu-spikedsoilahighlynegativecorrelationcoefficient(r=-0.5376)wasobtainedintheCuconcentrationbetweentheabovegroundpartandtheroot.ThismeantthattheCutolerantcultivarshadaweakabilitytotransferCufromtheirroottotheirabovegroundpart,andthereforestoredmuchmoreCuintheirrootthantheCusensitivecultivars.

  • 标签: 小白菜 栽培管理 毒性研究 菜园土壤
  • 简介:QuestionsconcerningthefunctionalroleofthehollowregionofthebutterflyPyrameisatalanta(L.)scaleareexperimentallyinvestigated.Attentionwasinitiallydirectedtothisproblembyobservationofthecomplexmicrostructureofthebutterflyscaleaswellasotherstudiesindicatinghigherliftonbutterflywingscoveredwithscale.Theaerodynamicforcesweremeasuredfortwooscillatingscalemodels.ResultsindicatedthattheaircavityofanoscillatingmodelofthePyrameisatalanta(L.)scaleincreasedtheliftbyafactorof1.15andreducedthedampingcoefficientsbyafactorof1.38.Themodificationoftheaerodynamiceffectsonthemodelofbutterflyscalewasduetoanincreaseofthevirtualairmass,whichinfluencedthebody.Thehollowregionofthescaleincreasedthevirtualairmassbyafactorof1.2.Thevirtualmassofthebutterflyscalewiththehollowregionwasrepresentedasthesumofairmassoftwoimaginarygeometricalfigures:acircularcylinderaroundthescaleandaright-angledparallelepipedwithinthehollowregion.TheinteractionmechanismofthebutterflyPyrameisatalanta(L.)scalewithaflowwasdescribed.Thisnovelinteractionmechanismexplainedmostgeometricalfeaturesoftheairpermeablebutterflyscale(invertedV-profileoftheridges,nozzleofthetipedge,hollowregion,andopeningsoftheupperlamina)andtheirarrangement.

  • 标签: 仿生学 蝶形 虚质量 生物研究
  • 简介:ThefractalcharacteristicsofthecanopystructureofB.gvmnorrhizapopulationareinvestigatedbyfractaldimensionanalysisintheNationalShankouMangroveNatureReserve.The3-year-oldbrancheshaveboxdimensionsbetween1.22and1.55,showingthecomplexitydegreeofbranchingstructureandtheabilityofoccupyingandutilizingecologicalspace.ItmaybeconsideredthatfractaldimensionprovidesausefulindexforthestudyoflightutilizationefficienciesandgrowthprocessesofB.gymnorrhiza.Calculatedbyusingthetwo-surfacemethod,thefractaldimensionsforthecrownpatternofindividualswithagesof20to50yearsrangefrom2.21to2.54,indicatingthatthefillingdegreeoffoliagetoatreecrownisrelativelylowandB.gymnorrhizahasthepropertyofasunplant.Alongwiththeincreaseofagesofindividuals,thefillingdegreeoffoliagetoatreecrownchangesfromhightolow,andsodoesthefractaldimension.Theboxdimensionsobtainedfromthegrayscalecurvesofpopulationcanopyarebetween1.47and1.61.Thegreatertheboxdimension,themorelooselyorganizedthecanopyspatialstructure,andthemorethelightspots.Thecanopystructuralinformationandcomplexityofapopulationcanbeeffectivelycapturedbyboxdimensionsobtainedfromcanopygrayscalecurves.

  • 标签: 分形特征 红树林 分维 海岸生态学 海洋科学 结构
  • 简介:芒麦草是一种外来入侵植物,在我国的分布范围随时间推移呈现不断扩大的趋势。通过对文献、网络资料的整理并结合实地调查案例,汇总了芒麦草目前的分布状况。结果表明:芒麦草已经在我国10个省(包括直辖市和自治区)22个市有自然分布。芒麦草具有很强的繁殖能力、适应性和竞争能力,容易在入侵生境中建植、扩繁、归化,进而发展成为入侵植物。通过对芒麦草入侵地和原产地生境类型的比较发现,芒麦草容易在受到人为干扰或者人为活动频繁的生境中建植,结合芒麦草生物学和生态学方面的特征,对其进行风险评估。欧洲风险评估体系(WG-WRA)中,芒麦草的入侵风险评估分值为28分,入侵等级为高度入侵风险Ⅲ;澳大利亚风险评估体系(WRA)中,其入侵风险评估分值为21分,对农业和环境的分值分别为13分和10分,是一种具有高度入侵风险的植物,需要加强预警工作和引起相关部门的重视。

  • 标签: 芒麦草 外来入侵植物 风险评估 入侵防控
  • 简介:Osteoporosisisametabolicskeletaldisorderleadingtobonefracturewhichadverselyimpactsthequalityoflife.Inthepresent,weaimedtoinvestigatetheeffectofPeperomiapellucida(L.)Kunthherbjuiceandethanolicextractonovariectomy(OVX)-inducedosteoporoticratmodel.OsteoporosiswasinducedbyOVXwithadoubledorsolateralapproachonfemaleWistarrats.FemaleWistarratsundergoingshamsurgeries(sham-controlgroup)servedascontrols.Theovariectomizedratsweredividedintosixgroupsbasedonadministeredtreatments,(i)CMCNa0.3%(OVX-controlgroup),(ii)standarddrug(ethynilestradiol4.5μg/kg),(iii)P.pellucidajuiceatdoseof50mg/kg,and(iv)100mg/kg,(v)P.pellucidaethanolicextractatdoseof50mg/kg,and(vi)100mg/kg.Treatmentswerestarted1weekafterthesurgeriesandlastedfor6weeks.Ratstreatedwith100mg/kgP.pellucidaethanolextracthadsignificantlydecreasedserumALPlevelandreducedexcretionofurinecalciumcomparedwiththeOVX-controlgroup(P<0.05).Theselevelswerenotsignificantlyalteredwhencomparedwiththesham-controlgroup(P<0.05).Furthermore,100mg/kgethanolicextract-treatedgroupshowedimprovementonthree-dimensionalimageofthetrabecularbonecomparedwiththeOVX-controlgroup.Trabecularcavityformationin100mg/kgethanolicextract-treatedgroupwasminimal.EthanolicextractofPeperomiapellucida(L.)Kunthherbsatadoseof100mg/kghadpreventiveeffectonOVX-inducedosteoporoticrats.

  • 标签: OSTEOPOROSIS OVARIECTOMY PEPEROMIA pellucida(L.)Kunth
  • 简介:新alkylenedihydrofuranglycoside(1)从根被孤立桑属albaL.吠叫,与moracinM-3鈥?O-尾-一起d-glucopyranoside(2),和moracinM-6,3鈥?di-O-尾-d-glucopyranoside(3)。化合物1作为2-methylene-3-methoxy-2被识别,5-dihydrofuran-4-O-尾-d-glucopyranoside根据包括1D和2DNMR的化学、分光镜的数据光谱分析。另外,1的抗氧化剂活动用1,1-diphenyl-2-picrylhydrazyl(DPPH)和2,2鈥?azinobis-3-ethylbenzothiazoline-6-sulphonic被评估酸(ABTS)试金。IC50价值分别地是2.49和0.45mg/mL。

  • 标签: 二氢呋喃 葡糖苷 抗氧化作用 烃基 树皮 桑树