简介:WereportamonolithicTm:YLFmicrolaserinthisLetter.Inordertoimprovetherelaxationoscillationofthelaser,bothendsofthecrystalarecoated,makingtheTm:YLFcrystalitselfaresonantcavity.Themicrolaserispumpedbya792nmlaserdiodeoperatedinthecontinuouswave(CW)mode.Weobtainmaximumoutputpowersof7.78and10.4Watthetotalincidentpowerof43.6Wwithfocuslensesof37.5and40mm,respectively,correspondingtotheslopeefficienciesof25.6%and40.0%andtheoptical–opticalconversionefficienciesof17.8%and23.8%.Itisclearthattheamplitudeoftherelaxationoscillationissmallerandthebeamqualityisbetterwiththefocuslengthof37.5mm;however,thelaserwiththefocuslengthof40mmproducesahigheroutputpowerandamorestablewavelengthcenteringat1878.44nm.
简介:AhighlyTm-dopedleadgermanateglassfiberisdevelopedusingtherod-in-tubemethod.The~2μmlaserbeamqualityofthefiberis~1.5.Theleadgermanatecompositefiberjumpersarehomemadeforallthefiberlaserinvestigations.Whencoreispumpedbya1590nmYb/Erfiberlaser,amaximumlaseroutputof313mWisachievedata670mWpumppower,andthecorrespondingslopeefficiencyis~52.8%.Moreover,byusinga2cmlongleadgermanatefiberasthegainmedium,a33mW1942nmTmlaserisalsodemonstrated.
简介:目的对比观察Firebird2TM药物洗脱支架和Excel药物洗脱支架治疗冠心病的长期疗效和安全性。方法纳入97例植入药物洗脱支架的冠心病患者,Firebird2TM支架组(52例)和Excel支架组(45例),分别于2014年12月15日-2014年12月25日对患者进行随访,平均随访时间35.95±15.99月。结局变量包括主要不良心血管事件(MACE,全因死亡、致死性心肌梗死、靶血管血运重建)和次要终点事件(心功能分级)。结果入组患者的平均年龄69.16岁,男性比例59.78%,两组患者的基线情况、入院时诊断、植入支架的直径和长度、冠状动脉病变情况、术前实验室检查项目比较差异均无统计学意义(P〉0.05)。随访后Firebird2TM支架组患者致死性心肌梗死1例,靶血管血运重建1例,全因死亡3例;EXCEL支架组患者致死性心肌梗死5例,靶血管血运重建3例,全因死亡5例,MACE发生两组组间比较差异无统计学意义(P〉0.05)。结论Excel药物洗脱支架长期治疗效果不优于Firebird2TM药物洗脱支架。
简介:目的结合不同标准和规范要求,对Petrifilm^TM沙门菌测试片(以下简称3M测试片)进行评价。方法用53个血清型的64株沙门菌及30株不同种属的非沙门菌,对3M测试片的包容性和排他性进行评价;针对12类食品样品,通过与我国国标方法的平行检测,对不同沙门菌检测系统的检验效果进行对比分析。结果64株沙门菌在所测试4种分离培养基上生长率差异有统计学意义(P〈0.05),4种沙门菌分离培养基对30株非沙门菌抑制效果也存在一定差异。不同沙门菌选择性增菌肉汤-选择性培养基组合可影响食品样品中10^-1cfu/25g染菌水平沙门菌的检出,差异有统计学意义(P〈0.05),其中以RV(R10)-3M测试片组合检出率最高,而两种选择性增菌肉汤-选择性培养基组合(如国标法)可提高不同种类食品样品中人工污染低浓度沙门菌的检出。结论3M测试片以其快速、方便、易保存,且准确性与国标方法相当的特点值得在食品微生物检测行业推广。
简介:Forenhancingthe2.0μmbandfluorescenceofHo3+,acertainamountofWO3oxidewasintroducedintoHo3+/Tm3+/Yb3+tri-dopedtelluriteglasspreparedusingmelt-quenchingtechnique.Thepreparedtri-dopedtelluriteglasswascharacterizedbytheabsorptionspectra,fluorescenceemissionandRamanscatteringspectra,togetherwiththestimulatedabsorption,emissioncross-sectionsandgaincoefficient.TheresearchresultsshowthattheintroductionofWO3oxidecanfurtherimprovethe2.0μmbandfluorescenceemissionthroughtheenhancedphonon-assistedenergytransfersbetweenHo3+/Tm3+/Yb3+ionsundertheexcitationof980nmlaserdiode(LD).Meanwhile,themaximumgaincoefficientofHo3+at2.0μmbandreachesabout2.36cm-1.Anintense2.0μmfluorescenceemissioncanberealized.
简介:AdetailedstudyofthefluorescenceemissionpropertiesandenergytransfermechanisminEr3+/Tm3+co-dopedleadsilicateglasseswasreported.Enhancednearinfrared1.8μmandvisibleup-conversionemissionswereinvestigatedunder808and980nmexcitations,respectively.TheenergytransfermechanismbetweenEr3+andTm3+wasanalyzedaccordingtotheabsorptionspectra,theemissionspectraandthelevelstructuresofEr3+andTm3+.TheenergytransferefficiencybetweenEr3+andTm3+reached68.1%intheEr3+/Tm3+co-dopedleadsilicateglasseswhenpumpedby808nmlaserdiode.Basedontheabsorptionspectra,theJudd-Ofeltparameters,spontaneousemissionprobability,absorptionandemissioncrosssections,gaincoefficientswerecalculatedandanalyzed.Itwasfoundthatthecalculatedemissioncrosssectionandthemaximumgaincoefficientaround1.8μmwere4.9×10–21cm2and1.12cm–1,respectively.TheseresultsindicatedthattheEr3+/Tm3+co-dopedlead-silicateglasseshadpotentialapplicationinnearinfraredlasers.
简介:Wedemonstrateadiode-pumpTm3+t-dopedall-fiberlaseroperatingat1908nmbasedonamasteroscillatorpoweramplifier(MOPA)configuration.Inourwork,152Woflaseroutputpowerisgeneratedbyatotalincidentpumppowerof434Wat790nm,correspondingtothetotalopticalefficiencyof35%.Thelaserwavelengthis1908.29nm.Tothebestofourknowledge,itisthehighestoutputpowerreachedaround1908nmwithsuchanarrowlinewidthof0.18nmbasedonaMOPAconfiguration.
简介:目的:分析免疫比浊法(My5-FU^TM法)和LC-MS/MS法测定胃癌患者服用替吉奥(S-1)后血浆中5-FU浓度,构建My5-FU^TM法测定服用替吉奥后5-FU的血药浓度。方法:30例初治胃癌患者首次服用替吉奥50mg,分别采用My5-FU^TM法和LC-MS/MS法测定口服替吉奥0、2、4、6、8、12h血浆中5-FU的浓度,获得患者的AUC0-12、AUC0-∞、Tmax、Cmax、T1/2。结果:My5-FU^TM法获得AUC0-12、AUC0-∞、Tmax、Cmax、T1/2分别为:(1109±488)ng·mL^-1·h,(1240±589)ng·mL^-1·h,(3.64±1.34)h,(196±69)ng·mL^-1和(2.52±1.34)h;LC-MS/MS法为:(614±280)ng·mL^-1·h,(656±318)ng·mL^-1·h,(3.58±1.27)h,(119±43)ng·mL^-1,(2.28±1.03)h。两种方法所获得药代动力学参数具有显著的相关性,血浆中5-FU的均值浓度变化差异显著(P=0.0045)。结论:My5-FU^TM法可以用于检测胃癌患者口服替吉奥后5-FU的血浆浓度,具有操作简便、快速、稳定性高等优点,也可用于服药替吉奥后5-FU药代动力学研究。