简介：Objective:Estimationofactivityaccumulatedintumorandorgansisveryimportantinpredictingtheresponseofradiopharmaceuticalstreatment.Inthisstudy,wesynthesized177Lutetium(177Lu)-trastuzumabironoxidenanoparticlesasadoubleradiopharmaceuticalagentfortreatmentandbetterestimationoforganactivityinanewwaybymagneticresonanceimaging（MRI）.Methods:177Lu-trastuzumab-ironoxidenanoparticlesweresynthesizedandallthequalitycontroltestssuchaslabelingyield,nanoparticlesizedetermination,stabilityinbufferandbloodserumupto4d,immunoreactivityandbiodistributioninnormalmiceweredetermined.Inmicebearingbreasttumor,liverandtumoractivitieswerecalculatedwiththreemethods:singlephotonemissioncomputedtomography（SPECT）,MRIandorganextraction,whichwerecomparedwitheachother.Results:Thegoodresultsofqualitycontroltests（labelingyield:61%±2%,meannanoparticlehydrodynamicsize:41±15nm,stabilityinbuffer:86%±5%,stabilityinbloodserum:80%±3%,immunoreactivity:80%±2%）indicatedthat177Lu-trastuzumab-ironoxidenanoparticlescouldbeusedasadoubleradiopharmaceuticalagentinmicebearingtumor.Resultsshowedthat177Lu-trastuzumab-ironoxidenanoparticleswithMRIhadtheabilitytomeasureorganactivitiesmoreaccuratethanSPECT.Conclusions:Co-conjugatingradiopharmaceuticaltoMRIcontrastagentssuchasironoxidenanoparticlesmaybeagoodwayforbetterdosimetryinnuclearmedicinetreatment.

简介：Analysisofmagneticpropertiesofmarinesurfacesedimentshasbeengraduallyprovedtobeoneoftheeffectivemeansforresearchingthesourceofmarinesediments.Inthispaper,samplesfrom39sitesinLiaodongBaywerecollectedtoanalyzethemagneticcharacteristicsofthesurfacesediments.MagneticstudyindicatedthatthesurfacesedimentsoftheLiaodongBayarecharacterizedbymagnetite.InthemiddleandeasternpartandthesouthwestcorneroftheBay,themainmagneticgrainswerecoarsemulti-domainandpseudo-single-domainparticles,whileinotherareassingle-domainandpseudo-single-domainparticlesconstitutethemajority.Basedongrainsizeandenvironmentalmagnetismdata,thecontentofmagneticmineralshasapositivecorrelationwiththehydrodynamicenvironmentwhenthemagneticmineraldomainisfiner.However,thecontentofmagneticmineralsisinacomplexrelationshipwiththehydrodynamicenvironmentinthecoarsemagneticdomainofmagneticmineralsfoundincentralLiaodongBayandplacesoutsidetheFuzhouBay,implyingthatthestronghydrodynamicenvironmentacceleratesthesedimentationofcoarsemagneticminerals.Basedongeographicpatternofmagneticproperties,itcanbeinferredthatthemainprovenanceofthesurfacesedimentsoftheLiaodongBayisthesurroundingrivers,andthecomparativeanalysisindicatesthatYellowRiversubstancesmaybealsoexistinthebay.

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简介：AmagneticanomalywasrecordedatEasterIslandon27February2010duringtheChiletsunamievent.Thephysicsofthemagneticanomalyisanalyzedusingkinematicdynamotheory.Usingasinglewavemodel,thespaceandtimebehaviorofthemagneticfieldisgiven.Byjointanalysisofthemagneticobservations,tidegaugedataandnumericalresultsoftheglobaltsunamipropagation,weshowthecloseresemblancebetweenthepredictedspatialandtemporalmagneticdistributionsandthefielddata,indicatingthemagneticanomalyatEasterIslandwasactuallyinducedbythemotionofseawaterundertsunamiwaves.SimilaritybetweenthefieldmagneticdataatEasterIslandduring2010Chiletsunamiandseasurfacelevelisverifiedwithrealistictsunamipropagatingmodel.

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简介：Objective:Thispaperaimstodesigningapulsedstrongmagneticfieldsgenerator.Methods:Alargevaluecapacitorwasusedtostoreelectricenergy,coilwasusedforproducingmagneticfields,maincontrol,circuitcontrolcharge,sampling,discharge,etc.Results:Thegeneratorprovidedapulsedmagneticfieldwiththeamplitudeofintensityfrom0.1-2Tandvariabletimeintervalofpulsefrom4s-1min.Itwasnotonlytobeoperatedeasilybutalsoperformedreliably.Conclusion:Thegeneratorwillbeappliedinspecialclinicaldiagnosis,therapyandotherfields.

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简介：现在的工作被奉献给在冻结的magnetar赋予以对一个电场直角的一个极端强壮的磁场的外壳中演变的波色子的学习，两个都由周期的功能描述了。我们沿着盎士通过一个维的潜在的障碍讨论量通道过程。KleinGordon方程的答案以Mathieu为可计算出来的粒子的精力范围，正在转弯从的功能被表示对指数地沿着盎士种模式摆动。在JeffreysWentzelKramersBrillouin框架以内，传播系数在不稳定性范围的中间为粒子动量被计算。

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简介：在一个应用磁场(MF)的影响下面，eigenenergies和地面和第一个激动的状态(GFES)的特徵函数被在联合不均匀的Gaussian潜在的量很好的强壮的electron-LO-phonon(AGPQW)使用Pekar类型(VMPT)的一个变化方法获得。这个AGPQW系统可以作为二水平的qubit被采用。数字结果显示了(i)当电子处于GFES的重叠状态位于时，我们在AGPQW获得时间进化和电子概率密度的并列变化，(ii)由于在AGPQW的生长方向的不均匀的潜力的存在，概率密度显示出双山峰配置，而仅仅有一个，如果监禁是在AGPQW的xy飞机的二维的对称的，达到顶点，(iii)oscilla

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简介：Thecurrentsheathvelocityin0.25TorrgaspressureofFilippovtypeplasmafocusisstudiedexperimentally.Byusingtwotridimensionalmagneticprobesontopoftheanodesurface,thecurrentsheathvelocityismeasuredforargon,oxygenandnitrogen.Additionally,theeffectofchargingvoltageonthecurrentsheathvelocityisstudiedinbothaxialandradialphases.Wefoundthat,themaximumcurrentsheathvelocitiesatbothradialandaxialphasesarerespectively4.33±0.28(cm/μs)and3.92±0.75(cm/μs)withargonastheworkinggasat17kV.Also,theminimumvaluesofcurrentsheathvelocityare1.48±0.15(cm/μs)attheradialphaseand1.14±0.09(cm/μs)attheaxialphasewithoxygenat12kV.Thecurrentsheathvelocityattheradialphaseishigherthanthatattheaxialphaseforallgasesandvoltages.Inthisstudy,variationofthefullwidthhalfmaximum(FWHM)ofmagneticprobesignalswithvoltageisinvestigatedfordifferentgasesatradialandaxialphases.

简介：TheoptoelectronicandmagneticpropertiesofpureHoMnO3andHo0.67T0.33MnO3(T=La,Y)alloysinhexagonalphasearetheoreticallyinvestigatedbyusingthefirst-principlescalculations.TheinvestigationsareperformedbymeansofthedensityfunctionaltheorythroughusingthespinpolarizedgeneralizedgradientapproximationplustheHubbardpotential(SPGGA+U,Ueff=3eV).ThestudiedmaterialHoMnO3exhibitstwoindirectbandgaps:1.58eVforthespinupstateand0.72eVforthespin-downstatealongtheS–GdirectionwithintheSPGGA+Uapproximation.ItisfoundthatthebandgapofpureHoMnO3forthespin-upstateincreaseswithincreasingLaandYdopants.Theresultsshowthatallofthestudiedmaterialshavesemi-metallicbehaviorsforthespin-upstateandsemiconductingcharacterforthespin-downstate.ThesubstitutionsofLaandYforHoinHoMnO3causethestaticdielectricconstant(ε0)toincreaseinthexdirectionbuttodecreaseinthezdirection.ThecalculatedopticalconductivityspectrumofHoMnO3inalowenergyrangeisingoodagreementwiththerecentexperimentaldata.

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简介：TheresistivityofHg0.89Mn0.11Tehasbeenmeasuredbythesuperconductingquantuminterferencedevicemagnetometerinthetemperaturerangefrom5to200Kundertheappliedmagneticfieldof1,2,4and6.5Tesla,respectively,comparedwiththatofno-magneticfield.Theresultsshowthattheresistivityincreaseswithincreaseappliedmagneticfieldathighertemperaturefrom80to200K,butdecreasesatlowertemperaturefrom5to25K.Thereexistsatransitiverangefrom25to80K,wherethevariationoftheresistivityshowsdifferenttendenciesdependingonthestrengthofmagneticfield.Maximumdifferenceofresistivityunder6.5Teslafromthatwithoutmagneticfieldinthetemperaturerangefrom30to200Kisonlyabout5Ω·cm,butitincreasesupto3ordersofmagnitudeat5K.TheanalysisshowsthatthevariationofresistivityofHg0.89Mn0.11Teunderthemagneticfieldisthealgebraicsumofthetransversedirectionmagnetoresistanceeffectandthesp-dexchangeinteractioneffect.TDRMEplaysmajorroleinthehightemperaturerange.However,withthedecreaseoftemperature,theeffectofsp-dEIontheresistivitygraduallyexceedsthatofthetransversedirectionmagnetoresistanceeffectthroughthetransitiverange,andbecomesthedominanteffectinthetemperaturerangefrom5to25K,whichleadstothedramaticdecreaseofresistivity.

简介：Objective:Humaninducedpluripotentstem(iPS)cellsexhibitgreatpotentialforgeneratingfunctionalhumancellsformedicaltherapies.Inthispaper,wereportforuseofhumaniPScellslabeledwithfluorescentmagneticnanoparticles(FMNPs)fortargetedimagingandsynergistictherapyofgastriccancercellsinvivo.Methods:HumaniPScellswerepreparedandculturedfor72h.Theculturemediumwascollected,andthenwascoincubatedwithMGC803cells.CellviabilitywasanalyzedbytheMTTmethod.FMNP-labeledhumaniPScellswerepreparedandinjectedintogastriccancer-bearingnudemice.Themousemodelwasobservedusingasmall-animalimagingsystem.Thenudemicewereirradiatedunderanexternalalternatingmagneticfieldandevaluatedusinganinfraredthermalmappinginstrument.Tumorsizesweremeasuredweekly.Results:iPScellsandthecollectedculturemediuminhibitedthegrowthofMGC803cells.FMNP-labeledhumaniPScellstargetedandimagedgastriccancercellsinvivo,aswellasinhibitedcancergrowthinvivothroughtheexternalmagneticfield.Conclusion:FMNP-labeledhumaniPScellsexhibitconsiderablepotentialinapplicationssuchastargeteddual-modeimagingandsynergistictherapyforearlygastriccancer.