简介：从连翘果实中分离了三种苯乙醇甙类化合物，ｃａｌｃｅｏｌａｒｉｏｓｉｄｅＡ（１），ｐｌａｎｔａｉｎｏｓｉｄｅＡ（２）和ｆｏｒｓｙｔｈｏｓｉｄｅＡ（３），用光谱方法鉴定了它们的结构。１和２系首次从本属植物中分离得到。通过１Ｈ１ＨＣＯＳＹ和１３Ｃ１ＨＣＯＳＹ对３的氢信号与碳信号进行正确归属，补充文献的不足。３能显著促进ＣｏｎＡ诱导的淋巴细胞转化，提示其具有增强免疫作用，该活性未见报导。

简介：从血盆草的水提取物的正丁醇部分分离得到两个微量酚甙，根据理化常数及波谱分析鉴定为异槲皮甙和紫云英甙。这两个化合物均为首次从该植物中分得。

简介：TwonewglycosidesnamedasternatosideA1andternatosideB2wereisolatedfromtherootsofRanunculusternatus,thestructuresweredeterminedby1Dand2DNMR,ESI-MStechniques,andchemicalmethods.

简介：试图以便识别HPTLC侧面(简历标记)，在种类水平，为粗略的药的鉴定和证实，HPTLC分离在AervalanataL的不同部分上被开始。从南方印度。屏蔽的方法初步的phytochemical被Harborne的方法做。HPTLC研究被执行跟随Harborne和瓦格纳等方法。乙醇acetate-ethanol-water(8：2：1.2)为glycosides作为活动阶段被采用。结果A的茎，叶子，根，花和种子的methanolic摘录。lanata与范围0.02～0.86与23不同Rf价值显示出glycosides的23种不同类型的存在。当时，在glycoside的一般的更高的度，差异在植物的部分被观察了与繁殖部分相比。glycosides的最大的数字(12)在茎(9)跟随的根被观察了。礼品的结果学习的结论补充了拥有几的学习植物的民俗的用法知道并且有简历活动的未知bioactive混合物。由孤立并且识别这些bioactive混合物，新药能被提出治疗各种各样的疾病。

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简介：二新benzofuranlignanglycosides，gelsemiunosideA和B，从GelsemiumelegansBenth的整个植物被孤立。他们的结构根据分光镜的证据被阐明。而且，gelsemiunosideA和B被看一个有势力由压制A375-S2房间的增长的细胞毒素的活动。

简介：Aseriesofporousresins(PYR)withdifferentcontentofpyridylgroupwereprepared,andtheirphysicalstructureandadsorptionpropertiesonthesteviaglycosideswerestudiedindetail.AftertheselectiveadsorptionofPYRresins,therebaudiosideAcouldbeseparatedfromtheothercomponentsofthesteviaglycosides,andanewmethodforobtainingpurerebaudiosideAisreported.

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简介：二新C-21steroidalglycosides，mucronatosidesM(1)和N(2)，从白前科植物mucronata的茎被孤立，和一已知的复合stephanosideM(3)。根据化学证据和广泛的分光镜的方法，包括一个维、二维的NMR，二新混合物的结构作为12-O-tigloyl-20-O-N-methylanthraniloylsarcostin3-O--D-glucopyranosyl-(14)被识别-6-deoxy-3-O-methyl--D-allopyranosyl-(14)-(-D-cymaropyranosyl-(14)--D-cymaropyranoside(1)，和12-O-cinnamoyl-20-O-nicotinoyl(20S)-pregn-6-ene-3(,5(,8,12,14(,17,20-heptanol3-O--D-glucopyranosyl-(14)-6-deoxy-3-O-methyl--D-allopyranosyl-(14)--D-cymaropy

简介：ThepresentstudywasdesignedtoisolateandcharacterizetheanalgesiccompoundsofArtemisasacrorumLedeb.TheEtOAccrudeextractsfromtheaerialpartsofArtemisasacrorumLedebwereseparatedbychromatographyandthestructuresofnewcompoundswereelucidatedbasedonspectralanalyses.Analgesicactivitiesoftheisolatedcompoundswereassessedinratswithhotplatetestandpawpressureassay.TwonewflavoneC-glycosides,namedasSacrorosideAandB(Compounds1and2)wereisolatedfromtheEtOAccrudeextractoftheaerialpartsofArtemisasacrorumLedeb.Theyshowedsignificantanalgesiceffects.Inconclusion,Compounds1and2arenewnaturalproducts,whichshowsignificantanalgesiceffectsinadose-dependentmanner.

简介：二phenylethanoidglycosides(PhGs)被高效第一次从Plantagoasiatica的天线部分孤立并且净化用乙醇acetate-n-butanol-ethanol-water的离心的分区层析(HPCPC)(0.5:0.5:0.1:1，v/v/v/v)。化合物2的化合物1和293.8mg的45.6mg的一个总数从P的n-butanol摘录的1341mg被净化。asiatica。当由electrospray电离的plantamajoside和acteoside或isoacteoside多在否定离子模式上演双人脚踏车团spectrometry(ESI-MSn)，二PhGs的结构尝试性地被识别。

简介：AbstractIntroduction:Tripterygium glycosides (TGs) have been widely used in China to treat diabetic nephropathy (DN); however, proof of their use is scarce. The present study aimed to evaluate the effectiveness and safety of adding TGs to angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs).Methods:By searching Embase, MEDLINE, Cochrane Library, SINOMED, China National Knowledge Infrastructure, VIP Information/Chinese Scientific Journals, and WANFANG databases, we identified previous studies that met the specific selection criteria and included them in the meta-analysis. Analyses were performed using Review Manager (version 5.3).Results:Nine randomized controlled trials were included in the final meta-analysis. Patients were compared before and after treatment with ACE inhibitors or ARBs plus TGs, or ACE inhibitors or ARBs alone. The results revealed that treatment with ACE inhibitors or ARBs plus TGs resulted in significantly greater reductions in 24-h urinary total protein (UTP) levels (trial duration <2 months, mean difference [MD]: -0.25; 95% confidence interval [CI]: -0.32, -0.18; trial duration between 2 and 6 months, MD: -0.39; 95% CI: -0.44, -0.33; trial duration >6 months, MD: -2.09; 95% CI: -2.89, -1.29) compared with treatment using ACE inhibitors or ARBs alone. Additionally, ACE inhibitors or ARBs plus TGs showed better results after longterm administration. Treatment with ACE inhibitors or ARBs plus TGs resulted in significantly greater reductions in serum creatinine (SCr) compared with ACE inhibitors or ARBs alone (MD: -9.87; 95% CI: -13.76, -5.97).Conclusion:In patients with DN, adding TGs to ACE inhibitors or ARBs significantly lowered both the 24-h UTP and SCr levels. Therefore, ACE inhibitors or ARBs plus TGs might improve the treatment of DN in patients.

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简介：Thenegativeionfastatombombardment(NIFAB)massspectraofmono-,di-saccharidesandglycosidesusingphenylboronicacid(PBA)asreagenthavebeenstudied.Intheionsource,PBAreactsstereospecificallywiththemoleculescontainingcis-vicinalglycolstoformcharacteristicions,fromwhichthestereo-isomersofsaccharidescanbedefinitelydistinguished.Disaccharidesandglyco-sideswithβ-glycosidiclinkageseemtobeunfavorabaletoreactwithPBA,therefore,bycomparisonoftheabundancesofthecharacteristicions,theconfigurationoftheglycosidiclinkageinthesecompoundsmaybeinferred.

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简介：ＳＴＵＤＩＥＳＯＮＧＬＹＣＯＳＩＤＥＳＸＶＩＩ─ＳＴＥＲＥＯＳＥＬＥＣＴＩＶＥＳＹＮＴＨＥＳＩＳＯＦ（２，６－ＤＩＭＥＴＩＩＯＸＹ－４－ＥＴＨＯＸＹＣＡＲＢＯＮＹＬ）ＰＨＥＮＹＬ６－Ｏ－ＡＣＥＴＹＬ－２，３，４－Ｏ－ＢＥＮＺＹＬ－β－Ｄ－ＧＬＵＣＯＰ...