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简介：Inthispaperthroughthecomprehensiveanalysisofthefactorsofenterprises'SCMperformance,thetargetsystemofenterprises'SCMperformanceevaluationisestablishedandthemethodoffuzzymultiplecomprehensiveevaluationisproposed.ThismethodconvertsthecomplicatedproblemsofSCMintoaquantitativeevaluationtargetbyusingfuzzysyntheticoperationsothatitcanevaluateenterprises'SCMperformancemorescientificallyandguideenterprises'SCMtoworkwell.

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简介：AbstractAspirin-exacerbated respiratory disease (AERD) patients with CRSwNP suffer from reduced quality of life, reduced economic productivity, and higher risk of depression and sleep dysfunction. These patients often require frequent medical and surgical therapy, including functional endoscopic sinus surgery for recalcitrant disease. Given this severity, anti-type 2 biologic treatments are being investigated for use in this subgroup of patients with CRSwNP, including Omalizumab and Dupilumab. Preliminary data suggests that SNOT-22 related quality of life improvements following treatment with biologics are comparable to the current standard of care in the short term, but there is a lack of long-term data and standardized regimen that makes direct comparison difficult. Biologic therapies additionally require continuous use to avoid recurrence, and currently cost many times more than existing medical or surgical therapies. Aspirin-Exacerbated Respiratory Disease (AERD) is a type 2 (Th2)-mediated inflammatory disease characterized by chronic rhinosinusitis (CRS), nasal polyposis, rhinorrhea and asthma exacerbated by nonsteroidal anti-inflammatory drugs (NSAIDs) or acetylsalicylic acid (aspirin/ASA).1 From a rhinologic standpoint, AERD patients are recognized as a subset of patients CRS with nasal polyps (CRSwNP), with AERD affecting approximately 1% of the United States population.2 Broadly, CRSwNP patients demonstrate derangements of several Th2 pathways, including dysregulation of the interleukin (IL)-4, IL-5, and IL-13. Cytokine levels are altered systemically, in the nasal mucosa, and in polyp tissue itself, while mast cells and eosinophils are also increased locally.3,4,5,6 From a rhinologic standpoint, patients with AERD are often considered to be among the most difficult to treat CRS patients, due to severity and disease recalcitrance.6 This is reflected at the cellular and molecular level; nasal polyps from patients with AERD have over 3 times as many eosinophils and higher IL-5 concentrations when compared to polyps taken from subjects with non-AERD CRS.7,8

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简介：一天晚上，妻子在厨房准备晚餐的时候，我们的小儿子拿着一张纸走向他母亲。上面写道：

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简介：ThepromulgationoftheRulesrepresentsacrucialsteptowardinstitutionalizationandstandardizationoftheminimumcostoflivingprogram,whichmarkstheendofthearbitrarinessinthetraditionalreliefbehavior.Inacountry,towhatdegreethecitizensenjoyhumanrights,itdependsonthelaw.Theminimumcostoflivingsystemhastobeensuredbylawinitsprogresstowardinstitutionalizationandstandardization.Thishasbeentestifiedbythehistoryofthedevelopmentofthesocialsecuritysystems,eitherinGermany,whichisregardedasapioneerinmodernsocialsecuritysystemsortheUnitedStates.

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简介：在许多机器学习应用程序，数据不是免费的，并且为每个数据项目有测试费用。为节俭的原因，最小化测试的某存在工作尝试花费了并且同时，保存一个给定的决定系统的一个特别性质。在这份报纸，我们指出一个人能负担得起的测试费用在一些应用是有限的。因此，一个人不得不牺牲各自的性质在一项预算下面保留测试费用。形式化这期，我们定义测试费用限制属性减小问题，在优化目的是最小化有条件的信息熵的地方。这个问题是test-cost-sensitive属性减小问题和0-1背囊问题的必要归纳，因此它是更挑战性的。我们基于信息获得和测试费用建议一个启发式的算法处理新问题。算法在四UCI上被测试(加利福尼亚大学-Irvine)有各种各样的测试的数据集花费了背景。试验性的结果显示唯一的userspecified参数的适当设置。

简介：WecontinuewithourForeignStudentSeries.Today,inpartten,wediscussthecosttoattendacollegeoruniversityintheUnitedStates.