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简介：Levels:LowintermediateProblems:InteachingsciencestudentsEnglish,onemayfinditthemostdifficulttogetthemtospeakinEnglish.Althoughspeakingisoneofthefourskillsrequired,itisoftenneglectedandgivenupbymoststudentsandteachersaswell.Itistruethattherearemanydifficultiesinorganizingsuchalargeclassas30-40studentstopractisewithinacomprehensivecourse.Evenifateacherdevotedmostoftheclasstimetooralpractice,thiswouldonlybeabouttwominuteswitheachstudent.Usinggamestoforcethemtospeakisoneofthesolutionstosolvetheproblem.

简介：撒开手，让孩子自己走。相信他们，一路会走好！

简介：小朋友们，看到秋天姐姐给你们的英语单词了吗？请根据这些英语单词，在图中找出相应的物品哦！现在，就开始吧。

简介：小朋友们，看到秋天姐姐给你们的英语单词了吗？请根据这些英语单词，在图中找出相应的物品哦！现在，就开始吧。

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简介：小朋友们，看到秋天姐姐给你们的英语单词了吗？请根据这些英语单词，在图中找出相应的物品哦！现在，就开始吧。

简介：Theintroductionoftheconceptofcitizenshipmakesitanecessaryconcepttoworkonanintegratednationalunityinlightofthechallengeswearegoingthrough,andmakecitizenshipanideaasaformofnationalcohesioninrepellingthemanyattacks.Thecitizenisthefirstgoalasitisconcernedwithnationalachievement,becauseitsabsencefromthecitizenisunderstandableandbehavioralistheabsenceofnationalunity.Inaddition,citizenshipisamajorfocusofmoderndemocratictheoryandpractice.Itisthebasisforthepromotionofdemocracy.Intheabsenceofcitizenship,democracyleadstoethnic,sectarian,andreligiousoutcomes,whicharebasedonthepublicinterestandtheresultingpoliticalandsocialdivisionandinstability.Itisimpossibletotalkaboutcitizenshipinthe21stcentury,inisolationfromcivilsocietyandthemodernnationalstate,thestateoflawandinstitutions,asanecessaryintroductiontothedemocraticstate.Citizenshipisitsbasicfoundation:Equalityandfreedomarewhatmakedemocracyacommunicationsystemopentoahumanhorizonasmuchasitisopentogrowthandprogress.Theconceptofa“globalcitizen”isstillemerging.Inthepoliticalanddiplomaticlanguage,peoplearestilltalkingabout“statenationals”andthe“stateofcare”thatcarefortheinterestsoftheircitizensanddefendtheirrightsnotonlyintheirterritorybutalsowherevertheyare,throughtheirembassiesandconsulates.

简介：从前，有一个农夫种了一片禾苗地。他总是嫌田里的庄稼长得慢，今天去瞧瞧，明天去看看，觉得禾苗总没有长高。他心想：有什么办法能使它们长得快些呢？突然他想到了一个主意。他把禾苗一棵一棵地往上拔，能快速让它们长高。

简介：InordertodevelopclinicaldiagnostictoolsforrapiddetectionofSARS-CoV(severeacuterespiratorysyndrome-associatedcoronavirus)andtoidentifycandidateproteinsforvaccinedevelopment,theC-terminalportionofthenucleocapsid(NC)genewasamplifiedusingRT-PCRfromtheSARS-CoVgenome,clonedintoayeastexpressionvector(pEGH),andexpressedasaglutathioneS-transferase(GST)andHisx6double-taggedfusionproteinunderthecontrolofaninduciblepromoter.WesternanalysisonthepurifiedproteinconfirmedtheexpressionandpurificationoftheNCfusionproteinsfromyeast.Todetermineitsantigenicity,thefusionproteinwaschallengedwithserumsamplesfromSARSpatientsandnormalcontrols.TheNCfusionproteindemonstratedhighantigenicitywithhighspecificity,andtherefore,itshouldhavegreatpotentialindesigningclinicaldiagnostictoolsandprovideusefulinformationforvaccinedevelopment.

简介：MissSmithissixty-fouryearsoldnow.Shelovedastrongyoungmanwhenshewasnearlytwenty.Shegavehimallbutthemantookallhermon-

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简介：这份报纸给有限维的无法缩减的操作员的概念((FDI)操作员)并且无限的维的无法缩减的操作员((IDI)操作员)。讨论关系(FDI)操作员，(IDI)操作员和强烈无法缩减的操作员((SI)操作员)并且说明操作员的三个班的一些性质。为有上面的三角形的操作员矩阵的形式的操作员的有限维的irreducibility的一些足够的条件被给。这份报纸证明有一个单条系列的每个操作符是小紧缩的不安一(FDI)在每围住的线性操作符T能被操作符接近在的可分离的Banach空格和表演(FDI)的操作员关于强壮操作员的拓扑学和每个紧缩的操作符K罐头的(X)由操作符接近了在(FDI)关于有一个Schauder基础的Banach空格X上的标准拓扑学的(X)，在此(FDI)(X):={TB(X)：T=i=1kTi,Ti(FDI)，k}。

简介：Cardiologistswhoseepatientsonageneralcardiologyservicearebeginningtoseeanincreasingnumberofpatientswhohavereceivedaprimarypreventionimplantablecardiacdefibrillator(ICD)buthaveneverhaditfire.ThereareadditionallyanumberofpatientswhohaveinappropriatefiringofICDs.Inappropriateshocksoccurinupto40%ofpatientswithanICD.Themaincauseissupraventriculartachyarrhythmia,includingsinustachycardia,atrialfibrillation,andotherrapidsupraventriculararrhythmias.

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简介：AbstractBackground:Psoriasis is a chronic inflammatory skin disease, affecting about 0.6% of the Chinese population. Many patients are not well controlled by conventional treatments, thus there is need for new treatment regimens. In this study, we assessed the efficacy and safety of secukinumab in Chinese patients with moderate to severe plaque psoriasis.Methods:This study was a 52-week, multicentre, randomized, double-blind, placebo-controlled, parallel-group, Phase 3 trial. A sub-population of study participants (≥18 years) of Chinese ethnicity were randomized to receive subcutaneous injections of 300 or 150 mg secukinumab, or placebo. The co-primary endpoints were psoriasis area severity index (PASI) 75 and Investigator’s Global Assessment (IGA) 0/1 at Week 12.Results:A total of 441 Chinese patients were enrolled in this study. Co-primary outcomes were achieved; 300 and 150 mg secukinumab were superior to placebo as shown in the proportion of patients that achieved PASI 75 (97.7% and 87.2% vs. 3.7%, respectively; P < 0.001), and IGA 0/1 (82.3% and 69.7% vs. 2.7%; P < 0.001) at Week 12. Treatment efficacy was maintained until Week 52. There was no increase in overall adverse events with secukinumab relative to placebo throughout the 52-week period. Conclusion: Secukinumab is highly effective and well tolerated in Chinese patients with moderate to severe plaque psoriasis.Trial Registration:ClinicalTrials.gov, NCT03066609; https://clinicaltrials.gov/ct2/show/record/NCT03066609.