简介：目的：观察结膜瓣遮盖联合虹膜嵌顿术治疗全层感染真菌性角膜炎的疗效。方法：分析2005-03/2011-04在邢台眼科医院行结膜瓣遮盖＋虹膜嵌顿术的深部真菌性角膜炎患者26例26眼,全部的病灶的范围均〈（5×5）mm2,角膜刮片检查真菌菌丝全部为阳性;前房积脓（＋）,病灶均较致密,术前不能确定病灶累及深度;在术中,当病灶剖切至接近后弹力层深度时,根据临床特点,对于病灶累及角膜全层,但直径≤1mm的患者,人为在残余病灶的近周边处刺透角膜,造成角膜穿孔,自角膜穿孔或破溃处注吸前房积脓和抛光内皮斑后,将相邻近的虹膜嵌顿在角膜穿孔处,并用缝线固定1～2针,最后行结膜瓣遮盖术,尽量保持水密,术后继续给予抗真菌治疗并密切观察。结果：患者26例中有5例在病灶剖切中自行破溃,3例在病灶剖切中不慎切透,18例角膜基质床在剖切过程中完整;结膜上皮恢复时间为13.44±2.21d;24例感染得到控制,成功率为92%;2例因感染未控制而改为角膜移植术,最终控制感染。结论：结膜瓣遮盖联合虹膜嵌顿术是治疗小范围的全层真菌性角膜炎的有效方法,它可以控制感染,为以后的增视手术创造条件,适合在基层医院开展。

简介：AIM:Tocharacterizetheclinicalfeatures,diagnosis,treatmentandprognosisofuveitisassociatedwithankylosingspondylitis(AS)inChinesepatients.·METHODS:TwohundredandthreepatientswithuveitisassociatedwithASfollowed-upintheThirdMilitaryMedicalUniversityDapingHospitalbetween2005and2010wereretrospectivelyevaluatedinthisstudy.Completeophthalmologicalexaminationswereevaluatedatbaselineandduringthefollow-upperiod.Thegender,age,follow-uptime,meanfrequencyofuveitisonset,andaccompanyingeyeexaminationfindings,history,demographicalparameterswerereviewed.Allthepatientspresentedcompleteclinicalandradiologic(sacroiliac,lumbar,dorsalandcervicalspine,knee,ankle,shoulder,hip,elbow)evaluation.HLA-B27typingwasalsosearched.·RESULTS:Therewere203patientsdiagnosedwithASassociateduveitis.AllshowedsacroiliacX-raychangesindicativeofAS.Therewere184maleand19femalepatients.Theaverageageofpatientswas35±12(range18-50).Meanfollow-upperiodwas2.4years(1-5years).Acuteanterioruveitiswasthemostcommontypeofuveitisinbothgenders.121eyespresentedunilateralinvolvement(55.2%),and92eyespresentedbilateralinvolvement(45.3%)withonsetalternately.22eyesoccurredhypopyon,16eyeswerefoundanteriorvitreouscells,7eyeswerenotedreactivemacularedemaorexudation,29eyespresentedposteriorsynechiaeofiris,and14eyespresentedcataract,9eyespresentedsecondaryglaucoma,2eyespresentedbendcornealdegenerationand1eyespresentedatrophyofeyeball.Atthefinalvisit,uveitiswaswellcontrolledinmostpatients.·CONCLUSION:ASassociatedwithuveitisinChinesepatientsmainlymanifestsasacuteanterioruveitis.AcombinationofcorticosteroidswithothermydriasisagentsiseffectiveformostASassociatedwithuveitispatients.Ingeneral,theprognosisisgoodinthesecases.

简介：目的探讨改良式小梁切除术联合丝裂霉素C治疗青光眼的临床疗效。方法应用改良式小梁切除术治疗42例（64眼）各型青光眼,术中一次性使用0.4mg/ml丝裂霉素C,术后随访6～12月,观察其临床疗效及其并发症。结果术后1月检查,58眼（90.6%）术后视力有不同程度的提高;术后1周测眼压,所有病例眼压均有不同程度的下降,有48眼（75.0%）眼压低于21mmHg,术后6月测眼压,54眼（84.6%）低于21mmHg;末次随访时,56眼（87.5%）形成弥散扁平的功能性滤过泡,8眼（12.5%）为非功能性滤过泡;总手术成功58眼（90.6%）,其中完全成功54眼（84.4%）,条件成功4眼（63%）,失败6眼（9.4%）。术后主要并发症为：角膜水肿5眼,前房渗出4眼。讨论改良式小梁切除术联合丝裂霉素C治疗青光眼,可有效地减少青光眼术后滤过道瘢痕的形成,充分降低眼压。该方法不需要特殊设备,手术时间短、损伤小,并发症少,手术效果好,是一种安全、有效的治疗青光眼方法。