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简介：APRIL2015ChinaPledgesEducation,Hospital,JurorSystemReformsOnApr.1,China’scentralauthoritiesrolledoutplanstosupportruralteachers,overhaulpublichospitalsandimprovepublicsupervisionofcourtcases.Theplanswereadoptedatthe11thmeetingofthecentralleadinggroupfordeepeningoverallreformonWednesday,duringwhichPresidentXiJinping,whoisalso

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简介：BeijinghasbeenoneoftheepicentersattackedmostseverelybytheSARS-CoV(severeacuterespiratorysyndrome-associatedcoronavirus)sincethefirstpatientwasdiagnosedinoneofthecity'shospitals.WenowreportcompletegenomesequencesoftheBJGroup,includingfourisolates(IsolatesBJ01,BJ02,BJ03,andBJ04)oftheSARS-CoV.ItisremarkablethatallmembersoftheBJGroupshareacommonhaplotype,consistingofsevenlocithatdifferentiatethegroupfromotherisolatespublishedtodate.Among42substitutionsuniquelyidentifledfromtheBJgroup,32arenon-synonymouschangesattheaminoacidlevel.Rootedphylogenetictrees,proposedonthebasisofhaplotypesandothersequencevariationsofSARS-CoVisolatesfromCanada,USA,Singapore,andChina,gaverisetodifferentparadigmsbutpositionedtheBJGroup,togetherwiththenewlydiscoveredGD01(GD-Ins29)inthesameclade,followedbytheH-UGroup(fromHongKongtoUSA)andtheH-TGroup(fromHongKongtoToronto),leavingtheSPGroup(Singapore)moredistant.ThisresultappearstosuggestapossibletransmissionpathfromGuangdongtoBeijing/HongKong,thentoothercountriesandregions.

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简介：1我叫编号1573，来自未来。在讲我为什么回到现在之前，我需要告诉你们未来的故事。2072年8月30日，我来到新家。

简介：TheR(replicase)proteinistheuniquelydefinednon-structuralprotein(NSP)responsibleforRNAreplication,mutationrateorfidelity,regulationoftranscrip-tionincoronavirusesandmanyotherssRNAviruses.Basedonourcompletegenomesequencesoffourisolates(BJ01-BJ04)ofSARS-CoVfromBeijing,China,weanalyzedthestructureandpredictedfunctionsoftheRproteinincomparisonwith13otherisolatesofSARS-CoVand6othercoronaviruses.TheentireORF(open-readingframe)encodesfortwomajorenzymeactivities,RNA-dependentRNApolymerase(RdRp)andproteinaseactivities.TheRpolyproteinunder-goesacomplexproteolyticprocesstoproduce15function-relatedpeptides.Ahydrophobicdomain(HOD)andahydrophilicdomain(HID)arenewlyidentifiedwithinNSP1.ThesubstitutionrateoftheRproteinisclosetotheaverageoftheSARS-CoVgenome.ThefunctionaldomainsinallNSPsoftheRproteingivedifferentphylogeneticresultsthatsuggesttheirdifferentmutationrateunderselectivepressure.ElevenhighlyconservedregionsinRdRpandtwelvecleavagesitesby3CLP(chymotrypsin-likeprotein)havebeenidentifiedaspotentialdrugtargets.Findingssuggestthatitispossibletoobtaininformationaboutthephy-logenyofSARS-CoV,aswellaspotentialtoolsfordrugdesign,genotypinganddiagnosticsofSARS.

简介：TheSixthEuropeanCommission(EC)andinternationalconferenceon‘Themanagementanddisposalofradioactivewaste':Euradwaste'04,washeldon29-31March2004inLuxembourg.

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简介：今天，吃过晚饭后，爸爸对我说：“碧君，我出道题考考你怎么样?”“没问题啊!”我高兴地回答。爸爸看我胸有成竹的样子，接着说：“题目是这样的：有9箱小球，其中混进了1箱次品，次品小球的外观与正品小球相同，只是每个小球的质量少了1克。已知每

简介：介绍了国家标准和行业标准编号的构成、标准的性质以及标准编号的读法。

简介：孩子们特别爱玩拼图．但他们往往把一套套的拼图材料弄乱，每次找起来都要花费许多时间。为了解决这个问题，我在每一套拼图的图片背面都用笔编一个数字号码，不同套的图片使用不同的数字号码。这样找起来就容易了，能干的孩子就可以完成。

简介：推出2004歙的蒙迪欧是长安福特在岁末年初之即做出了两大举动之一。

简介：现在的硬盘市场越来越复杂,自从Quantum公司的桌面硬盘部门被PC硬盘界老大Maxtor收购之后,硬盘的发展速度越来越快,无论是5400转的还是7200转的,IBM、Seagate、Maxtor、WestDigital等公司都纷纷推出它们自己的最新型号产品,由于硬盘种类繁多,同品牌、不同品牌之间,各种硬盘外型都非常相似,如

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