简介:Aseriesofnovel1H-benzimidazol-1-ylacetatesand1H-benzimidazol-1-ylpropionatescontaining1H-1,2,4-triazolemoietyweresynthesizedundermicrowaveirradiationbymulti-stepreactions,inyieldsof87-94%.TheirinvitroantifungalactivitiesagainstBotrytiscinereaandSclerotiniasclerotiorumwereevaluatedbymycelialgrowthratemethod.AllthetargetcompoundsexhibithighactivitiesagainstB.cinereawiththeEC50valuesof7.96-21.74μg/mL,higherthanthatofcarbendazim.
简介:1IntroductionFullerenehasreceivedconsiderableattentionandagreatresearchinginterestduetoitsuniquestructureandinterestingproperties[1-3].Manyfunctionalgroupshavebeenintroduced,oftenregion-orstereo-selectively,fortuningthephysicalpropertiesofC60andforconstructingsupramoleculararchitectures[4-6].AmongallkindsofC60derivatives,thediseoticmolecule-substitutedC60derivativesshowinterestingproperties,especially,liquidcrystalproperties.Uptonow,fewC60derivativeswithdiscotic-moleculargroupsandtheirliquidcrystalpropertieshavebeenstudied.In1996,Deschenauxetal.[7]reportedthefirstmesomorphicC60-ferrocenederivative.Tianetal.[8]synthesizedaC60-perylenederivativein2004.Nakanishietal.[9]preparedaseriesofuncommonliquidC60derivativeswith2,4,6-tris(alkyloxy)benzalgroupsin2006.Lately,Geertsetal.[10]describedthesynthesisofmesogenicphthalocyanine-C60.
简介:Anon-linearoptical(NLO)materialwassynthesizedbymeansofasimplemethod.Thismaterialcanbeappliedinelectro-optical(EO)devices,suchasEOswitchesandmodulators.TheDisperseRed1(DR1)wasdopedinpolymethyl-methacrylate-co-glycidylmethacrylate(PMMA-co-GMA)astheNLOactivechromophore.Thesynthesisprocessandmaterialstructurewereexpressed.Thethermalproperties,surfacemorphologyandopticalcharacteristicsofthematerialwereinvestigatedbymeansofdifferentialscanningcalorimetry(DSC),thermogravimetricanalysis(TGA),atomicforcemicroscopy(AFM),andm-linestechnique.Usingthereflectiontechnique,thevalueoftheelectro-opticalcoefficientγ33wasmeasuredas11pm/Vatawavelengthof1310nm.AnEOswitchwithnanosecondresponsebasedonthismaterialhasbeenfabricated.
简介:Asupramolecular1Dferromagneticsystemwasstudiedexperimentallyaswellastheoretically.Hybriddensityfunctionaltheory(DFT)calculationswerebasedontheX-rayanalysis.TheresultsofDFTcalculationsandMcConnellmechanismhavecontributedtotheunderstandingofthefactorsgoverningtheexchangecouplingofmagnetisminthecrystalpacking.Boththeexperimentalevidenceandtheoreticalcalculationindicatethatspindensityin2-iodonitronylnitroxide(INN)radicalsconfirms1Dferromagneticchainwithinter-chainantiferromagneticinteraction.
简介:应用分子力学、半经验量子化学RM1方法优化了32个抗野生型HIV-1病毒毒株的二芳基嘧啶类(DAPYs)化合物分子结构,从分子构象模型中提取了多种参数并结合疏水性参数与指示性参数建立QSAR多元线性回归方程.回归方程显示:分子体积V的增大会降低其抑制活性,而左苯环与嘧啶环间二面角日增大可以提高抑制活性.同时指示性参数工表明左苯环CN基团加入可以明显增加抑制活性,嘧啶环上R1位置苯基与硝基的加入可以极大降低抑制活性.
简介:Poly(4-vinylpyridine)supportednanoparticleofcopper(Ⅰ)iodideisreportedasagreenandrecyclablecatalystfortheregioselectivesynthesisof1,4-disubstituted-1H-1,2,3-triazolesfrombenzylhalides,sodiumazideandterminalalkynesinwater.Thiscatalystcanberecoveredbysimplefiltrationandrecycledupto8consecutiverunswithoutanylossofitsefficiency.