简介：

简介：Generally,ROSareregardedashostdefensemoleculesthatarereleasedbyneutrophilstodestroyexogenouspathogenssuchasbacteriaandtoactassecondarymessengersinsignaltransduction.However,increasedproductionofROSisalsoinvolvedininducingpathophysiologicalchangessuchasapoptosis,cellcycledisruption,andnecrosis.Forthisreason,inductionofROS-mediateddamageincancercellsbypharmacologicalagentsthateitherpromoteROSgenerationordisablethecellularantioxidantsystemisconsideredapotentialtherapeuticstrategyforpreferentiallykillingcancercells[1].

简介：

简介：

简介：Rapidgrowthofmannedspaceflightresultsinmoreconcernabouthealthriskandanurgentneedofhealthassessmentinspacetravel.Sincetheimportanceofbrainfunctionstoastronauts,weexploredthelong-termeffectsandpotentialmechanismsof56Feionradiationonmicebrain.

简介：Understandingthehealtheffectsofexposuretospaceradiationisofparticularimportancebecauseofthemountinginterestindeepspaceexploration.Heavyionssuchas56Fearemainradiationsourcesindeepspace,whichcouldposeasignificanthazardtospaceflightcrewsduringandaftermissions[1].ComparedtoX-rays,56FeionshasthemostdeleteriouseffectsonsurvivalandlevelsofDNAdamage[2].

简介：Weperformfirst-principlecalculationsforthestudyoftheorthorhombicRb2Cd2(SO4)3structure.Electronicenergybands,totalandpartialdensitiesofstatesarereportedandanalysed.Itisfoundthatoxygenatomic2pelectronsstronglyhybridizewithRb/orCd4dandS2pstates,resultingintwo-typeionicgroupswithweakcouplings.Itisshownthatmacroscopicdomainwallsoriginatefromsuchweak-couplingionicgroups,arisingatthecellboundaries.Theasymmetriccationbonds(Rb-OandCd-O)andthesubsequentrotationsoftheS04tetrahedracanleadtothedrivingforceoftheferroelectricbehaviour.Thepredictedpyroelectriccurrenteffectsareobservedexperimentallyintheferroelectricphase.

简介：