简介：AIM:Todescribetheinvolutionpatternsofvesselgrowthofretinathroughfluoresceinangiography(FA)ofchildren,whohadbeenundertreatmentupto1ypreviouslyintravitrealranibizumab(IVR)asmonotherapyforretinopathyofprematurity(ROP).METHODS:Thisisaretrospectivestudy.ThemedicalinformationandFAof17children(34eyes)whoseareaofavascularretinafromtheoraserratawasmorethantwodiscdiameters(DD)wereanalyzed.RESULTS:Among34eyes,allwerethepresenceoffinger-shapedvesselsandarteriolar-venularshunts(100%,34/34eyes).Popcornabnormalitieswerefoundinmostoftheeyes(94.1%,32/34eyes).Furthermore,inmanycases(23.5%,8/34eyes),therewereleakagepersistingintheregionofthejunctionbetweenavascularandvascularretina.Incontrast,just2eyes(5.9%)showeddamageofretinalcapillarybedand3eyes(8.8%)showedlargeareaofretinalpigmentepithelium(RPE)atrophy.CONCLUSION:AlthoughIVRcanbeveryeffectiveinROP,weshouldremaincautiousasinfantsmayremainavascularperipheralretinasandabnormalvessel.FAallowsaccuratevisualizationofvesselabnormalitiesineyeswithROP,whichwillbehelpfultoaffectassessmentofdiseaseactivityandtherapeuticeffect.