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500 个结果
  • 简介:M2/GDP ,0-100%. ,S/GDP 

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  • 简介:Stroma-freehemoglobin(SFHb)waspreparedfromfreshorout-datedwholebloodbylysingredcells.Atdifferenttemperatures,pyridoxal5-phosphate(PLP)wasaddedina4:1molar-ratiototheHbtetramerfollowedbyreductionwithNaBH4underN2for16hrssubsequentcrosslinkingbyglutaraldehydeinpresenceoflysinefor14-16hrs.Yieldedsolublepyridoxalatedpolyhemoglobin(PolyHb-P).5%-20%gradientSDS-PAGEshowedthechangeoftheHbmolecularweight(MW)aftercrosslinking.GelchromatographyshowedthatthepolyHb-Phadacontinuousdistributionofmolecularweightwiththerangefromabout65,000to600,000Dalton.ThepolyHb-Psolutionprovidedanornaloxygencarryingwith23.1ofP50atpH7.24or26.1ofP50atpH7.24.

  • 标签: 制备 维生素B6 吡哆醛 血色素 化学修正
  • 简介:与搏动在magneto-hydro-dynamic泵为充分发达的流动驱动器的稳定性在这糊一个分析解决方案横向的Eletro磁性的领域被介绍。做这,流动的一个理论模型被开发,分析结果被获得因为两个都对合适的圆柱、笛卡儿的配置在海洋的容器的推进使用。管理寓言的动量PDE用近似速度分发被转变成一个平常的微分方程。数字结果被获得,asymptotic分析被造发现答案的数学行为。在为斯图亚特数字,电磁的相互作用数字,雷纳兹数字,方面比率,以及磁性、电的尖频率和阶段角度的移动的各种各样的价值的magneto-hydro-dynamic泵对时间的最大的速度被介绍。结果证明为一个高级斯图亚特数字,为在流动的某个方向的液体流动的稳定性有频率限制。这稳定性频率依赖于一条隧道的几何参数。

  • 标签: 稳定性 推进系统 磁流体 电磁相互作用 流体流动 常微分方程
  • 简介:Thetechnologyofactivationbyaddingfewactivators(<1%)toincreasetheamountofblendsincementwasinvestigated.Theresultsshowthatouteractiva-tionhasaremarkableeffectonimprovingthephysicalpropertiesofslagcement,flyashcementandvolcaniccement.Forexample,thecompressivestrengthwasincreasedby5-10MPa.Morever,theapplicationofactivationisbeneficialtogrind-aiding,earlystrengthandwater-reducingetc.

  • 标签: BLENDS grinding-aiding EARLY strength water-reducing
  • 简介:Inthepaperhomogeneousparticleboardofwheatstrawisresearched.Theresultshowsthetechnologyofhomogeneousparticleboardfromcostandquality.Themoisturecontentofstrawparticleis2.0%~2.5%.Thetemperatureofhot-pressingis150℃.Thetimeofhot-pressingis48sec/mm(panelthickness).TheratiobetweenMDIandUFis0.40.Thegluecontentforsurfacelayerofwheatstrawparticleis10%(MDI2.86%,UF7.14%).Thegluecontentforcorelayerofwheatstrawparticleis8%(MDI2.29%,U...

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  • 简介:本项研究从仿红细胞出发,将增加双分子脂膜亲水性的PEGPE(聚乙二醇与磷脂酰乙醇胺的衍生物)及增加双分子脂膜硬度的SM(神经鞘磷脂)掺入脂质体,比较其在体外稳定性、体内分布及清除半衰期。结果证明该类脂质体稳定性提高,体内被肝、脾清除减少,血循环中半衰期显著延长。本研究为脂质体载药至非网状内皮系统的靶向给药打下基础。

  • 标签: 脂质体 亲水性修饰 硬度修饰
  • 简介:Tumormetastasisisthedominantcauseofdeathincancerpatients.However,themolecularandcellularmechanismsunderlyingtumormetastasisarestillelusive.Theidentificationofproteinmoleculeswiththeirexpressionscorrelatedtothemetastaticprocesswouldhelptounderstandthemetastaticmechanismsandthusfacilitatethedevelopmentofstrategiesforthetherapeuticinterventionsandclinicalmanagementofcancer.Proteomicsisasystematicresearchapproachaimingtoprovidetheglobalcharacterizationofproteinexpressionandfunctionundergivenconditions.Proteomictechnologyhasbeenwidelyusedinbiomarkerdiscoveryandpathogeneticstudiesincludingtumormetastasis.Thisarticleprovidesabriefreviewoftheapplicationofproteomicsinidentifyingmolecularfactorsintumormetastasisprocess.Thecombinationofproteomicswithotherexperimentalapproachesinbiochemistry,cellbiology,moleculargeneticsandchemistry,togetherwiththedevelopmentofnewtechnologiesandimprovementsinexistingmethodologieswillcontinuetoextenditsapplicationinstudyingcancermetastasis.

  • 标签: 蛋白质组 肿瘤 转移 鉴定 基质辅助激光解吸电离飞行时间质谱
  • 简介:Experimental Study of Decay of Hot NucleiExperimentalStudyofDecayofHotNuclei¥WangSufang;TanJilian;SongMingtao;ZhangChong;HeZh...

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  • 简介:Phosphatdylcholinesandtheiranalogs,thefunctionalbuildingblockofthemembrane,arerecentlyfoundtomediatemultiplephysiologicalprocessesandexhibitabroadrangeofdesirablepharmacologicaleffects,whichinvolvehydrophobiclipophilicinteractions(HLI)betweenthephospholipidandthecellmembrane.TheHLIbehaviorofphosphatJdylcholines(Ln)andtheiranalogues1,2-diacyl-sn-glycerol-3-phosphoricacidbromoethylester(Pn),havebeeninvestigatedinMeOH-H20binarysystemsofdifferentvolumefractions(designatedasΦ)oftheorganiccomponent,byemployingα-nephthylethyllaurylether(Np-12)asfluorescentprobe.AveryinterestingobservationisthattheLnpossessesdoublecharacter,i.e.,itbehavesbothasanaggregatorandasadeaggregator.Theeffectsofthestructureandtheenvironmentonthecoaggregationanddeaggregtionarealsodiscussed.

  • 标签: 卵磷脂 解聚行为 聚合行为 疏水亲油性 生理学 药理效应
  • 简介:Macro-trafficmodelisaneffectivetoolforsupportingtrafficprogrammertoThisarticleisbasedonthesoftwareproductsVISEM(demandmodel)andVISUM(supplymodel)fromPTVCompanyofGermany,andstudiesmacro-trafficmodelonthebasisofconsideringthattrafficsystemisaninteractivesystemofbetweenasupplysystemandademandsystem.

  • 标签: 宏通信量 需求模型 供应模型 VISUM PTV
  • 简介:China'smalemarriagesqueezeanditspotentialconsequencehaveattractedmuchattentionandgivenrisetodebate,butmoststudiescontributethissqueezetosexstructureandneglecttheagestructure,andsomestudiesuseflawedmethodtostudythecontributionofagestructureinthissqueeze.InthispaperwedevelopanindicatorofSpousalSexRatio(SSR)andapplyadecompositionmethodintoageandsexstructure.BasedonthedatafromChina's2010censusandprojection,wepredictthatfrom2010to2020,theagestructurewillbethedominantfactorforChina'smalemarriagesqueeze,andfrom2020to2034,thecontributionofsexstructurewillbeincreasing,whereasthatofagestructurewillbedecreasing.From2034to2045,China'smalemarriagesqueezewillmainlyfromimbalancedsexstructure,andtheagestructurewillcontributelittleornegativelytoChina'smalemarriagesqueeze.

  • 标签: 挤压 中国 婚姻 年龄结构 性别结构 分解方法
  • 简介:Asaresultofmoreandmoreseriousenergyrisks,thestudyofnationalenergysecurityzoningisnotonlythebasicrequirementofenergyriskmanagementbutalsothenewdemandofeconomicdevelopmentfortheenergyindustry.Firstly,thispaperanalyzesthebasicsituationofenergyresourcesandproductionandconsumptionofpri-maryenergyfrom1996to2005inChina.Secondly,thispaperfoundsanEnergySecurityIndexSystemformedbysixindicesincludingthepercentageofenergyreserves,interlocaldependentdegree,energyelasticitycoefficientandsoon.Itsubsequentlycalculatestheweightoftheseindiceswiththefactoranalysisratingmethod.Lastly,thepaperevaluatesandzonestheabilitiesofenergysecurityof30provincesinChinawiththegreyclustermethod.Accordingtotheirsecurity,the30provincesareclassifiedintothreedifferentlevels:high,medium,andlowlevels.TheregionsatlowenergysecuritylevelincludeBeijing,Shanghai,Zhejiang,Fujian,Guangdong,GuangxiandHainan.Theyaremainlylittoralandshortofprimaryenergyproductionwhilemostlydependentonotherprovinces.Thoseatmediumenergysecuritylevelinclude15provinces(citiesordistricts),suchasLiaoning,Tianjin,Hebei,Shandong,Henan,Hunanandsoon.Theseprovincesareinthenortheast,north,eastofandcentralChina.Thoseathighenergysecu-ritylevelcontainShanxi,InnerMongolia,Heilongjiang,Jilin,Chongqing,Sichuan,Shaanxi,Xinjiang.Theseprov-incesarethemainprimaryenergyproductionbases.

  • 标签: 中国 能源危机 能源安全 能源管理