简介：摘要： 飞机风挡加温功能与飞行安全密切相关，风挡温度的准确采集直接关乎风挡加温功能的正常工作。TMS320F28377片内包含丰富的AD转换资源，利用片内AD实现了多路风挡温度传感器的高速采集。该设计与传统的利用外置AD的设计方法相比，简化了电路设计，提高了电路的基本可靠性。经工程实践证明，该设计采集精确，工作稳定可靠。

简介：摘要：在F县展望十四五规划和2035远景目标，必须在脱贫攻坚取得胜利后，接续全面推进乡村振兴，实施乡村产业提升行动。本文通过分析乡村产业振兴战略的相关意义与内涵，基于 SWOT分析法对F县乡村产业振兴的基本情况、优势、劣势、机会和潜在威胁进行了深入分析，提出了乡村产业振兴的有关发展建议。

简介：摘要：燃气-蒸汽联合循环机组具有效率高、排放清洁等特点，现今越来越多地被应用于区域供热。本文分析了适合燃气-蒸汽联合循环机组供热的几种方式，从中压缸抽汽、中低压连通管抽汽、冷段抽汽、背压供热、压力匹配器入手，分析其供热特点、使用条件及投运项目，最后总结了针对不同的热负荷特点可选用的供热方式。

简介：AbstractObjective:Metabolic disorders are markedly common in women with polycystic ovary syndrome (PCOS), and nonalcoholic fatty liver disease (NAFLD) is observed in 30%-55% of all PCOS patients. Many studies have reported that autophagy and apoptosis, which are closely related to mitochondrial function, play important roles in the development of NAFLD. Therefore, in this study, we aimed to explore the role of mitochondrial dysfunction caused by liver apoptosis and autophagy imbalance in the development of NAFLD in a PCOS mouse model.Methods:We used a dihydrotestosterone (DHT)-induced PCOS model to mimic the pathological process of hyperandrogenism. Hematoxylin and eosin and Oil Red O staining assays were used to observe the pathological changes in the liver. Western blotting and quantitative real-time polymerase chain reaction were used to perform mitochondrion-related assays.Results:Hepatic steatosis and different degrees of inflammation were observed in the DHT-treated mice. The expression of molecules involved in the respiratory chain and aerobic respiration process was altered. The levels of the key molecules associated with apoptosis and autophagy were abnormal.Conclusions:Androgens may play a role in the process of hepatic steatosis development by affecting mitochondrial function and subsequently inducing apoptosis and autophagy. Such phenomena might be involved in the pathogenesis of NAFLD in women with PCOS.

简介：AbstractBackground:Delivery room resuscitation assists preterm infants, especially extremely preterm infants (EPI) and extremely low birth weight infants (ELBWI), in breathing support, while it potentially exerts a negative impact on the lungs and outcomes of preterm infants. This study aimed to assess delivery room resuscitation and discharge outcomes of EPI and ELBWI in China.Methods:The clinical data of EPI (gestational age [GA] <28 weeks) and ELBWI (birth weight [BW] <1000 g), admitted within 72 h of birth in 33 neonatal intensive care units from five provinces and cities in North China between 2017 and 2018, were analyzed. The primary outcomes were delivery room resuscitation and risk factors for delivery room intubation (DRI). The secondary outcomes were survival rates, incidence of bronchopulmonary dysplasia (BPD), and risk factors for BPD.Results:A cohort of 952 preterm infants were enrolled. The incidence of DRI, chest compressions, and administration of epinephrine was 55.9% (532/952), 12.5% (119/952), and 7.0% (67/952), respectively. Multivariate analysis revealed that the risk factors for DRI were GA <28 weeks (odds ratio [OR], 3.147; 95% confidence interval [CI], 2.082-4.755), BW <1000 g (OR, 2.240; 95% CI, 1.606-3.125), and antepartum infection (OR, 1.429; 95% CI, 1.044-1.956). The survival rate was 65.9% (627/952) and was dependent on GA. The rate of BPD was 29.3% (181/627). Multivariate analysis showed that the risk factors for BPD were male (OR, 1.603; 95% CI, 1.061-2.424), DRI (OR, 2.094; 95% CI, 1.328-3.303), respiratory distress syndrome exposed to ≥2 doses of pulmonary surfactants (PS; OR, 2.700; 95% CI, 1.679-4.343), and mechanical ventilation ≥7 days (OR, 4.358; 95% CI, 2.777-6.837). However, a larger BW (OR, 0.998; 95% CI, 0.996-0.999), antenatal steroid (OR, 0.577; 95% CI, 0.379-0.880), and PS use in the delivery room (OR, 0.273; 95% CI, 0.160-0.467) were preventive factors for BPD (all P < 0.05).Conclusion:Improving delivery room resuscitation and management of respiratory complications are imperative during early management of the health of EPI and ELBWI.

简介：AbstractBackground:Diabetes mellitus (DM) is an important risk factor in the long-term outcomes of surgical revascularization. However, few studies have focused on patients with ischemic heart failure (IHF) and DM, and the results are controversial. This study aimed to evaluate the effect of DM on the long-term outcomes of IHF patients undergoing coronary artery bypass grafting (CABG).Methods:In this propensity-matched study, data of IHF patients who underwent CABG in our hospital from January 2007 to December 2017 were analyzed. With a mean 73-month follow-up time, the patients were divided into two groups according to whether they had DM. The primary endpoint was all-cause death, and the secondary endpoint was a composite of all-cause death, stroke, recurrent myocardial infarction, and revascularization.Results:There was no significant difference in all-cause mortality between the two groups (5.8% vs. 4.1%, P = 0.216). The incidence of main adverse cardiovascular and cerebrovascular events (MACCE) in the secondary endpoint was significantly higher in the DM group than that in the non-DM group (10.4% vs. 8.1%, P = 0.023).Conclusions:DM can negatively affect the long-term outcomes of IHF patients undergoing CABG by significantly increasing the overall incidence of MACCE, though the long-term survival does not show a significant difference between the DM and non-DM patients.

简介：AbstractBackground:To present a surgical technique for the treatment of intradural extramedullary (IDEM) tumors by using endoscopically controlled surgery with open hemilaminectomy technique.Methods:In this study, 20 patients with 22 IDEM tumors were enrolled. An endoscopically controlled surgery with open hemilaminectomy was employed to remove the tumors. Data related to clinical symptoms and medical images before and after surgery were collected for perioperative evaluation and follow-up analysis.Results:All the tumors in 20 patients were well removed. The clinical symptoms were significantly reduced in all the patients as well. The short-term follow-up data showed that there was no tumor recurrence or spinal deformity.Conclusion:The endoscopically controlled surgery with open hemilaminectomy technique provided favorable exposure and satisfactory resection to the IDEM tumors. It may be an effective surgical method for treating IDEM tumors. Larger samples and longer follow-up data are needed to verify its long-term effectiveness.

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简介：AbstractBackground:Computed tomography (CT) and magnetic resonance imaging (MRI) data can be fused to identify the tumor boundaries. This enables surgeons to set close but tumor-free surgical margins and excise the tumor more precisely. This study aimed to report our experience in performing computer navigation-aided joint-preserving resection and custom-made endoprosthesis reconstruction to treat bone sarcoma in the diaphysis and metaphysis of the femur and tibia.Methods:Between September 2008 and December 2015, 24 patients with bone sarcomas underwent surgical resection and joint-sparing reconstruction under image-guided computer navigation. The cohort comprised 16 males and eight females with a median age of 19.5 years (range: 12-48 years). The tumor location was the femoral diaphysis in three patients, distal femur in 19, and proximal tibia in two. The tumors were osteosarcoma (n = 15), chondrosarcoma (n = 3), Ewing sarcoma (n = 3), and other sarcomas (n = 3). We created a pre-operative plan for each patient using navigation system software and performed navigation-aided resection before reconstructing the defect with a custom-made prosthesis with extracortical plate fixation.Results:Pathological examination verified that all resected specimens had appropriate surgical margins. The median distance from the tumor resection margin to the joint was 30 mm (range: 13-80 mm). The median follow-up duration was 62.5 months (range: 24-134 months). Of the 24 patients, 21 remain disease free, one is alive with disease, and two died of the disease. One patient developed local recurrence. Complications requiring additional surgical procedures occurred in six patients, including one with wound hematoma, one with delayed wound healing, one with superficial infection, one with deep infection, and two with mechanical failure of the prosthesis. The mean Musculoskeletal Tumor Society score at the final follow-up was 91% (range: 80%-100%). The 5- and 10-year implant survival rates were 91.3% and 79.9%, respectively.Conclusions:Computer navigation-aided joint-preserving resection and custom-made endoprosthesis reconstruction with extracortical plate fixation is a reliable surgical treatment option for bone sarcoma in the diaphysis and metaphysis of the femur and tibia.

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简介：摘要纸质报告或其电子版报告是影像医师与转诊医师的主要沟通方式。报告的内容不仅影响患者的管理和临床结果，而且可以作为法律性文件用于医疗纠纷的评判，用于证明医疗的必要性、计费的准确性和监管的合规性。融合显像的复杂性使得完成一份高质量的PET/CT报告可能较其他影像学检查报告困难。该文讨论了一份简洁、完整的18F-脱氧葡萄糖(FDG)PET/CT肿瘤显像报告应具有的基本要素，并通过日常临床实践中的例子对这些要素进行阐述。

简介：摘要：本文讨论了以STM32F4为控制平台的停车场自动泊车系统的基本总体构架，以及通过运动控制系统、防碰撞系统和定位导航系统的设计，实现AGV的自动泊车。经实验证明，该系统能够准确识别车位，实时为自动泊车系统提供外部环境参数，准确高效率实现自动泊车。

简介：摘要：分析探讨GE 6F燃机所用压气机的喘振成因及保护原理，包含在具备孤岛功能机组上所采用的预防措施。

简介：摘要：国有企业在国民经济和人民生活中的地位都是举足轻重的，为我国的经济建设做出了巨大的贡献。

简介：摘要：文中针对一种厚膜混合集成F/I流量转换器电路进行了理论分析，详细介绍了电路的设计原理、结构，及关键技术攻关情况，并进一步论证了F/I流量转换器电路批产化和高可靠的设计原则，同时也对该行业优势及其发展方向进行了相关探讨。

简介：摘要：润滑油是9F燃气轮机中必备的用品，同时在运行工作中也是最容易出现问题的部分，其中漏油现象比较常见，并且在此过程中漏油现象对于整体运行又具有一定影响作用，因此相关建设人员需要对此问题高度重视，以此提高9F燃气轮机运行的效率和质量。基于此本文对9F燃气轮机的透平轴承漏油问题进行分析研究，主要针对机组漏油原因进行分析，此内容与油封间隙过大有一定关联，后续压力问题也是引起漏油现象的主要原因。其次针对不同的漏油原因给予了具有针对性的解决措施，通过各类方案的优化，整体机组出现漏油现象的概率减小，因此此类问题也被解决。结合本文内容可以对燃油汽轮机出现的问题进行完善，因此也为后续汽轮机设计提供了整改思路。

简介：摘要：对涡桨飞机来说，其螺旋桨加温系统非常重要，少数涡桨飞机发生螺旋桨烧蚀故障，从而导致飞机停场问题，加上需要对桨叶进行更换，航空公司遭受了严重的经济方面的损失。本文在分析MA60飞机螺旋桨的加温应用的基础上，分析了它的电器元件的安装以及电气构成，进而对螺旋桨加温系统进行改进。

简介：【内容摘要】 为提高F级燃气--蒸汽联合循环机组的运行效率，实现节能降耗，从机组参数优化，夏季部分负荷运行优化等方面进行全面分析，结合本项目主要承担调峰运行功能，年运行小时数及利用小时数偏低，不建议增加较多设备初投资进一步提高汽机进汽参数。通过调整燃机IGV水平，选择合理的燃机燃烧器系统，加热入口空气等方式提高联合循环机组部分负荷效率。

简介：AbstractBackground:Hyperthermia in combination with DnaJA4-knockout (KO) obviously affects the anti-viral immunity of HaCaT cells. The mechanisms of this process are not yet fully explored. However, it is known that DnaJA4 interacts with actin cytoskeleton after hyperthermia. Our aim was to investigate the effects of DnaJA4 on F-actin in HaCaT cells following hyperthermia.Methods:Wild-type (WT) and DnaJA4-KO HaCaT cells were isolated at either 37°C (unheated) or 44°C (hyperthermia) for 30 min followed by testing under conditions of 37°C and assessing at 6, 12, and 24 h after hyperthermia. The cytoskeleton was observed with immunofluorescence. Flow cytometry and Western blotting were used to detect the expression of F-actin and relevant pathway protein.Results:DnaJA4-KO and hyperthermia changed the cytoskeleton morphology of HaCaT cells. F-actin expression levels were elevated in DnaJA4-KO cells compared with WT cells (6364.33 ± 989.10 vs. 4272.67 ± 918.50, P < 0.05). In response to hyperthermia, F-actin expression levels of both WT and DnaJA4-KO cells showed a tendency to decrease followed by an obvious recovery after hyperthermia (WT cells: unheated vs. 6 h after hyperthermia or 24 h after hyperthermia: 0.34 ± 0.02 vs. 0.24 ± 0.01, 0.31 ± 0.01, P < 0.001, P < 0.05; DnaJA4-KO cells: unheated vs. 6 h after hyperthermia or 24 h after hyperthermia: 0.44 ± 0.01 vs. 0.30 ± 0.01, 0.51 ± 0.02, P < 0.001, P < 0.01). WT cells restored to baseline levels observed in the unheated condition, while DnaJA4-KO cells exceeded baseline levels in the recovery. As the upstream factors of F-actin, a similar profile in rho-associated serine/threonine kinase 1 (ROCK 1) and RhoA expressions was observed after hyperthermia. While E-cadherin expression was decreased in response to hyperthermia, it was increased in DnaJA4-KO cells compared with WT cells.Conclusions:Hyperthermia affects the expression levels of F-actin in HaCaT cells. DnaJA4 knockout increases the expression of F-actin in HaCaT cells after hyperthermia. DnaJA4 regulates the expressions of F-actin and the related pathway proteins in response to hyperthermia in HaCaT cells.

简介：摘要：本文从三菱M701F4燃机燃烧系统结构、燃烧控制逻辑、操作步骤，以及在调整过程中燃烧稳定性的变化规律这四个方面解析了三菱M701F4燃机燃烧调整关键技术。M701F4燃机主要通过调整值班燃料流量和旁路空气流量来重新确认燃机在运行时的燃烧稳定性裕度，调整对象仍然是基准温控线。燃调负荷点的确定原则是在常用负荷段以及高负荷段的间隔尽可能小。值班燃料量的调整范围是±0.5%，旁路空气的调整范围是±5%。在高负荷下，在旁路阀开度和值班阀开度下调的过程应缓慢操作。