简介:SpokecavitieshavebeendevelopedandhaveapparentadvantagesforhighcurrentprotonacceleratorbasedonFig.1(coloronline)Theelectromagneticfielddistribution.superconductivityatlowandmediumenergyregion.Astheresearchandthetechnicalreserve,InstituteofModernPhysics(IMP)hasstartedtheR&Dprogramofadoublespokecavity(operatingfrequency325MHz,0=0.52),withintheframeworkofChinaAcceleratorDrivenSystem(C-ADS)project.TheRFdesignandmechanicalstructuredesignhavebeenfinished,andtwoprototypecavitiesweremanufacturedinHarbin.
简介:Wehavestudiedthetwo-andthree-photonabsorption(2PAand3PA)propertiesofMn-dopedCsPbCl3twodimensionalnanoplatelets(2DNPs)andcubicnanocrystals.Comparedwiththeircubiccounterparts,theMn-doped2DNPsexhibitstrongerquantumconfinementeffectsthatcanmoreefficientlyenhancetheirdopantcarrierexchangeinteractionsandmultiphotonabsorption.Morespecifically,themaximumvolume-normalized2PAand3PAcrosssectionsofthe2DNPswere6.8and7.2timesgreaterthanthoseoftheircubiccounterparts,respectively,reachingupto1237GM∕nm3inthevisiblelightbandand2.24×10-78cm6·s2·photon-2∕nm3inthesecondbiologicalwindow,respectively.
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简介:AbstractBackground:Clinical observational studies revealed that 99Tc-methylene diphosphonate (99Tc-MDP) could reduce joint pain and swollenness in rheumatoid arthritis (RA) patients. This multicenter, randomized, double-blind, double-dummy study aimed to evaluate the effects of 99Tc-MDP plus methotrexate (MTX) vs. MTX alone or 99Tc-MDP alone on disease activity and structural damage in MTX-naïve Chinese patients with moderate to severe RA.Methods:Eligible patients with moderate to severely active RA were randomized to receive 99Tc-MDP plus MTX (n = 59) vs. MTX (n = 59) alone or 99Tc-MDP (n = 59) alone for 48 weeks from six study sites across four provinces in China. The primary outcomes were the American College of Rheumatology 20% improvement (ACR20) response rates at week 24 and changes in modified total Sharp score at week 48.Results:At week 24, the proportion of participants achieving ACR20 was significantly higher in the MTX+ 99Tc-MDP combination group (69.5%) than that in the MTX group (50.8%) or 99Tc-MDP group (47.5%) (P = 0.03 for MTX+ 99Tc-MDP vs. MTX, and MTX+ 99Tc-MDP vs.99Tc-MDP, respectively). The participants in the MTX+ 99Tc-MDP group and the 99Tc-MDP group had significantly less important radiographic progression than the participants in the MTX group over the 48 weeks (MTX + 99Tc-MDP vs. MTX: P = 0.03, 99Tc-MDP vs. MTX: P = 0.03, respectively). There was no significant difference in terms of adverse events (AEs) among the groups. No serious AEs were observed.Conclusions:This study demonstrated that the combination of 99Tc-MDP with MTX inhibited structural damage and improved disease activity in RA patients compared with MTX and 99Tc-MDP monotherapies, without increasing the rate of AEs. Additional clinical studies of 99Tc-MDP therapy in patients with RA are warranted.Trial Registration:Chictr.org, ChiCTR-IPR-14005684; http://www.chictr.org.cn/showproj.aspx?proj=10088.
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简介:我们在场对为在两倍井的ultracold波色子的物理政体的彻底的描述,与专辑,注意付钱到宏观的重叠(MS)。我们使用多达八个单个粒子模式的Lipkin-Meshkov-GlickHamiltonian的归纳学习这些MS,解决有数字准确diagonalization和高顺序的不安理论的联合的Hamiltonian。MS在左、正确的潜在的井之间;有同时位于井并且在仅仅二个模式的所有原子的极端情况是著名中午状态,但是我们的途径包含更一般的MS。更单个的粒子模式的使用把维数带进这个问题,允许我们将难限制放在通常在文学对待的原来的二模式的LMG模型的使用上,并且也介绍混合Josephson-Fock政体。更高的模式与不同尖性质介绍自由和MS状态的尖度。
简介:InMarch2013,theEUandJapanopenedtwostrategicnegotiations—theEU-JapanStrategicPartnershipAgreement(SPA)talksandtheEU-JapanFreeTradeAgreement(FTA)negotiations.TheEUhasfocuseditsattentiononFTAnegotiations,butJapanismoreinterestedinsecuritycooperationandsohasfocusedmoreontheEU-JapanSPA.Thesestrategicdual-tracknegotiationswillalsoinfluencethestrategicorderandeventuallyrestrictEU-Chinarelations.
简介:一个容易的方法被介绍制作monodisperse磁性的macroporous聚合物祷告(MMPB)。Waterin-油高度内部阶段乳剂(抱起对方的大腿把他摔倒)被使乳化准备在包含单体的一个油阶段的水的铁离子答案。抱起对方的大腿把他摔倒被介绍进一台简单microfluidic设备制作monodisperse(water-in-oil)-in-water两倍乳剂微滴。微滴用作microreactors综合Fe<潜水艇class=“a-plus-plus”>3O<潜水艇class=“a-plus-plus”>4nanoparticles并且是联机polymerized形成MMPB。准备MMPB显示制服尺寸,互连的多孔的结构,superparamagnetic行为和Fe的一致分发<潜水艇class=“a-plus-plus”>3O<潜水艇class=“a-plus-plus”>在聚合物矩阵的4。MMPB被扫描电子显微镜学(SEM)描绘,Fourier变换红外线的光谱学(FTIR),X光检查衍射(XRD),传播电子显微镜学(TEM),颤动的样品magnetometry(VSM)。我们相信这个方法是在准备macroporousnanocomposite祷告的一种通用技术。
简介:Anewmethodformeasuring3-Drigidbodydisplacementsisproposed,inwhichtwoperpendicularbeamsareemittedontotwosensitiveplanesofPSDsleingperpendiculartoeachother.Themethodcanbeusedtomeasure1-Dor2-Ddisplacementswhenrequired.Moreover,theexperimentalresultsarepresented,whichdemonstratethatthenewmethodhashighaccuracy,fastprocessingspeed,highreliability,andeasilybeingrealized.
简介:Mobileoffshoredouble-causewaypiersystem,atypeofseashoreunloadingequipment,consistsoftwogroupsofmultipleconnectedsemi-submersiblemodules.Thisstructurehaswideapplicationbecausemostofthemiddleorminitypeofvesselsandshipscanbemooredtoit.Basedontheanalysisofcomputationalmethodsofmulti-bodymotionresponse,ahydrodynamicmodelissetupandthethree-dimensionalpotentialtheoryinfinitedepthisadoptedtocalculatethethree-dimensionalmotionresponseofthissystem.ThedoubleP-Mspectrumisusedtoanalyzethemotionresponseinirregularwaves.Differentwavedirectionsarespeciallytakenintoconsideration,duetotheirvariouseffectstothemotionresponse.Furthermore,thecalculatedresultiscomparedwiththatoftheexperiment,anditisprovedthatsway,heave,pitchandyawmotionaregreatlyconstrainedbymooringsystem.Thecomparisonalsoindicatesthatthemodelcanforecastthemotionperformanceofthetarget,andthatthecalculatedresultcanalsobeusedasreferenceinconnectorandmooringsystemdesign.
简介:Inthispaper,weaimatdynamicalbehaviorsofastochasticSISepidemicmodelwithdoubleepidemichypothesis.Sufficientconditionsfortheextinctionandpersistenceinmeanarederivedviaconstructingsuitablefunctions.WeobtainathresholdofstochasticSISepidemicmodel,whichdetermineshowthediseasesspreadwhenthewhitenoisesaresmall.Numericalsimulationsareusedtoillustratetheefficiencyofthemainresultsofthisarticle.
简介:Layereddoublehydroxides(LDHs)areaclassoflayeredinorganicmaterialsthatconsistofstructurallypositivelychargedlayersandexchange-ableanionsintheinterlayergalleryforchargebal-ance.ThedelaminationofLDHsisdecidedbysyn-thesismethodtosomeextent.Inthiswork,LDHsaresynthesizedviathreedifferentroutesandtheirdelaminationpropertiesarecharacterized.Co-precipitationmethodion-exchangemeth-
简介:Globalseismicitycatalogsaresufficientforcharacterizingdoubleseismiczones(DSZs)insubductingslabandfacilitatetoestimatelayerseparationwithoutinconsistentuncertaintiesaslocalcatalogs.PreviousstudieshaveshownthecorrelationbetweenDSZslayerseparationandplateagewhilecorrelationforthoseyoungerthan~60Maissuspicious.ThelackingofDSZswithlayerseparationlessthan10kmfurthermakesitdifficulttopreciselyestimatesuchcorrelation.Thus,weincorporateeightDSZsdatadeterminedthroughlocalseismicityintoglobally-determineddatasetandreexaminesuchcorrelation.Thebestfittingresultsshowthatbothalinearmodelandasquarerootofplateagecanmathematicallyfitthelayerseparationwell.However,itisdifficulttodistinguishthesetwomodelswhenplateageisgreaterthan~20Masincetheirdifferenceislessthan2km.However,ifextrapolationispossible,bothmodelsshouldprovidephysicalinformationthatDSZswillnotformifthereisnosubductinglithosphere.Asaresult,theDSZscannotbeproduceduntiltheoceaniclithosphericagebecomesgreaterthan0.9Mainthesquarerootmodelwhilethelinearmodelgivesamisleadingresult.Assuchthesquarerootmodeldemonstratestherelationshipphysicallybetterthanthelinearone,itstillneedsfurthertestinthefuturewithmoreavailabledata,nevertheless,ourstudymightalsoprovideevidenceforthesuggestionthattheplateageisaprimarycontrolfactoroftheDSZsgeometryaswellasthesubductingprocesswhichdisregardsanylocaltectonicstresses.