简介：巴黎欧莱雅开启男士护肤新时代男性肌肤也有晦暗、缺水、油光满面等问题的困扰。巴黎欧莱雅男士极速激活型肤露，蓝色水润睹喱质地内含水量80％，缓解缺水肌肤；突破性Multi．L粒子科技瞬间激活皮肤活力，隐藏面部瑕疵，展现男性健康自然肤色。

简介：ＴＨＥＳＴＡＴＵＳＡＮＤＴＲＥＮＤＯＦＬＡＰＡＲＯＳＣＯＰＩＣＳＵＲＧＥＲＹＩＮＣＨＩＮＡＴＨＥＳＴＡＴＵＳＡＮＤＴＲＥＮＤＯＦＬＡＰＡＲＯＳＣＯＰＩＣＳＵＲＧＥＲＹＩＮＣＨＩＮＡＧａｏＹｉ；ＹａｎｇＪｉ－Ｚｈｅｎ（ＤｅｐａｒｔｍｅｎｔｏｆＳｕｒｇｅ...

简介：Objective:Population-basedcancerregistrationdatawereusedtoanalyzetheepidemiologyandtrendofmalignantmesotheliomainChina,andtheresultwouldprovidebasicdataforitspreventionandcontrol.Methods:Malignantmesotheliomadatain2013wereretrievedfromthedatabaseofNationalCancerRegistry.Malignantmesotheliomaincidenceandmortalitywereestimatedusingage-specificratebyurban/ruralandgenderaccordingtothenationalpopulationin2013.Malignantmesotheliomadatafrom22cancerregistrieswereusedfortrendanalysisduring2000–2013.Results:Itisestimatedthattherewere2,041newmalignantmesotheliomacasesand1,659malignantmesotheliomadeathsoccurredin2013.ThecrudeincidencerateinChinawere1.50/106(males1.67/106,females1.32/106),age-standardizedincidenceratesbyChinesestandardpopulation(ASIRC)andbyworldstandardpopulation(ASIRW)were1.03/106and1.02/106,respectively.ThecrudemortalityrateinChinawas1.22/106(males1.67/106,females1.32/106),age-standardizedmortalityratesbyChinesestandardpopulation(ASMRC)andbyworldstandardpopulation(ASMRW)were0.83/106and0.81/106,respectively.TherewasanincreasingtrendofincidencerateformalignantmesotheliomainregistrationareasofChinaduring2000–2013withannualpercentagechange(APC)of2.5%[95%confidenceinterval(95%CI):0.6%–4.5%].Afteragestandardization,nosignificantdifferenceswereobserved.Nomatterforcrudemortalityratesorage-standardizedmortalityrates,nosignificantdifferenceswereobservedduring2000–2013.Conclusions:Malignantmesotheliomaisthemajoroccupationalandenvironmentalneoplasmassociatedwithasbestosexposure.Theincreasingincidencetrendsuggeststhatmoreattentionshouldbepaidonthisdisease.

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简介：EpidemiologicalstudiesshowedtheincidencemortalityratesofcancerwereincreasinginrecentdecadesinChinesepopulation.Nationalandregionalpreventiveprogramsaimtoreducethehealthhazardsofcancerandfocusethepopulationathighrisksforspecificcancer,particularlyinruralareasandtooffertheaccesstoearlydetectionformultlplecancersinurbanareas.Theearlyscreening,earlydetectionandtreatmenthavebeenputintooperationforthepopulationatrisksinruralareasatfirst,andintheurbanareasinrecentyears.Tounderstandtheepidemicpatternsandtrendsofcancer,andtheexperiencesinapplyingearlydetectionstrategiesinChina,selectedliteratureswerereviewedforbriefsummary.

简介：钝肾的损伤的管理一直在演变。过去的管理主要基于分级系统的损伤(AAST)的外科的美国协会，即要求了计算断层摄影术(CT)扫描。尽管CT扫描使用正在增加并且变得调查的标准化模式，分级的AAST不再在外科的干预的决定起唯一的作用。保守方法成功地管理的钝肾的损伤的二份案例报告被介绍。当与一顶头盔和完整的保护的设备在20km/h骑一辆机器脚踏车时，大小写一是有下降的1820岁的男孩。他被他的左胁腹打到岩石上。对比揭示的腹的CT4厘米，等级III脾的眼泪和等级IV与大perirenalhaematoma离开了肾损害。他的国际严厉分数(ISS)是34。他与床休息和监视的经常的浆液血色素保存地被管理。有推迟的对比的随后的CT与与等级IV肾的损害一致的尿溢出揭示了稳定的perirenalhaematoma。当他意指时，大小写二是在一条跑道上有一个马达自行车事故的4020岁的男性80～100km/h，穿一顶头盔。他失去了控制并且撞击了到跑道的sidewall上。对比揭示的腹的CT有大尿溢出的等级IV左肾的损害。他的肾的损害与间隔保存地被管理腹部的推迟的阶段CT。腹部上的重复CT被执行在没揭示剩余urinoma的起始的损害以后的五个月。在这学习，而且，到钝肾的损伤的管理的文学的评论被进行表明增加如此的损伤的保守管理的趋势。额外的放射学的参数可以指导未来决策。然而，数据的适用性可以被限制直到使随机化的试用是可得到的。

简介：AbstractBackground:The outbreak of coronavirus disease 2019 (COVID-19) has become a pandemic causing global health problem. We provide estimates of the daily trend in the size of the epidemic in Wuhan based on detailed information of 10 940 confirmed cases outside Hubei province.Methods:In this modelling study, we first estimate the epidemic size in Wuhan from 10 January to 5 April 2020 with a newly proposed model, based on the confirmed cases outside Hubei province that left Wuhan by 23 January 2020 retrieved from official websites of provincial and municipal health commissions. Since some confirmed cases have no information on whether they visited Wuhan before, we adjust for these missing values. We then calculate the reporting rate in Wuhan from 20 January to 5 April 2020. Finally, we estimate the date when the first infected case occurred in Wuhan.Results:We estimate the number of cases that should be reported in Wuhan by 10 January 2020, as 3229 (95% confidence interval [CI]: 3139–3321) and 51 273 (95% CI: 49 844–52 734) by 5 April 2020. The reporting rate has grown rapidly from 1.5% (95% CI: 1.5–1.6%) on 20 January 2020, to 39.1% (95% CI: 38.0–40.2%) on 11 February 2020, and increased to 71.4% (95% CI: 69.4–73.4%) on 13 February 2020, and reaches 97.6% (95% CI: 94.8–100.3%) on 5 April 2020. The date of first infection is estimated as 30 November 2019.Conclusions:In the early stage of COVID-19 outbreak, the testing capacity of Wuhan was insufficient. Clinical diagnosis could be a good complement to the method of confirmation at that time. The reporting rate is very close to 100% now and there are very few cases since 17 March 2020, which might suggest that Wuhan is able to accommodate all patients and the epidemic has been controlled.

简介：Aim:ThedataonsemenanalysisofsubjectsattendingtheFertilityClinicatNIHFW(NationalInstituteofHealthandFamilyWelfare)Munirka,NewDelhiforthelast11yearswereanalyzedtoverifytheclaimsandspeculationsondecliningspermcountsinmen.Methods:Approximately10%oftherecordseveryyearstartingfrom1990to2000(numbering1176intotal)wererandomlyselectedforanalysis.Subjectswithazoospermiaorsevereoligozoospermiawereexcludedfromanalysis.Results:Theaverageageofthemenattendingtheinfertilityclinicwas31.2years.Theaveragesemenvolumeandspermcountwerefoundtobe(2.6±0.1)mLand(60.6±0.9)×10^6/ml.,respectively.Nosignificantdeclineinspermcountswasobservedinanyyearduringtheentirestudyperiod.Only1.8%ofthetotalnumberofspermcountsintherandomsamplingwerelessthen20×10^6/mL.OnthebasisofWHOcriteriaonmotility,thetotalpercentageofnon-progressiveandnon-motilespermintheejaculatewashigher(63%)ascomparedtothecombinedcategoriesofslowandrapidlinearprogressive.Conclusion:Thepresentstudyhasconfmnedsimilarfindingsfromotherdifferentcountriesthatdecliningspermcountsinhumansisnotaglobalphenomenon.(AsianJAndrol2003Sep;5:221-225)

简介：AbstractBackgrounds:Cardiovascular disease (CVD) remains the leading cause of deaths nationwide. However, little is understood about its temporal trend and corresponding influence on longevity improvements. We aimed to describe the updated tendency in CVD mortality and to quantify its impact on life expectancy (LE) increase in China.Methods:All-cause mortality rates were calculated with population sizes from the National Bureau of Statistics and death counts from the National Health Commission. We estimated CVD mortality rates by allocating age- and sex-based mortality envelopes to each CVD subtype based on its proportion derived from the Disease Surveillance Points system. The probability of CVD premature deaths and LE were calculated with life tables and we adopted Arriaga’s method to quantitate age- and cause-specific contributions to LE gains.Results:During 2013 to 2018, the age-standardized mortality rate of CVD decreased from 289.69 (95% confidence interval [CI]: 289.03, 290.35)/100,000 to 272.37 (95%CI: 271.81, 272.94)/100,000, along with a decline in probability of CVD premature deaths from 9.05% (95%CI: 9.02%, 9.09%) to 8.13% (95%CI: 8.10%, 8.16%). The gap in CVD mortality across sexes expanded with more remarkable declines in females, especially for those aged 15 to 64 years. Among major subtypes, the probability of premature deaths from hemorrhage stroke declined fastest, while improvements of ischemic stroke and ischemic heart disease were limited, and there was an increase in stroke sequelae. LE in China reached 77.04 (95%CI: 76.96, 77.12) years in 2018 with an increase of 1.38 years from 2013. Of the total LE gains, 21.15% (0.29 years) were attributed to reductions of CVD mortality in the overall population, mostly driven by those aged >65 years.Conclusions:The general process in reducing CVD mortality has contributed to longevity improvements in China. More attention should be paid to prevention and control of atherosclerotic CVD and stroke sequelae, especially for the elderly. Working-age males also deserve additional attention due to inadequate improvements.

简介：在循证医学中RCT被认为是临床治疗、干预措施效果评价的最佳证据来源，原因是源于其设计原理。研究单位被随机化地分配到不同的干预组，经过一段时间的干预后，与对照组相比，根据不同干预组间结局的不同，推断干预效果与干预措施的因果关系。