简介:ThetalentistheenginefactorforShanghaiwhiletransformingtheeconomicdevelopmentmodelinthe12the-five-year-planperiod.TodaythetalentdevelopmentstrategyinShanghaiisnotonlyfacingthegreatchallengesfrominternationalmetropolisanddomesticcities,butalsoexistsaseriesofstructuralproblemsforitself.Toacquireandmaintainitscompetitiveadvantagesinaneraofglobalbrainbattleinfuture,Shanghaineedstodefinitelyorientitsmissiontowardsaglobaltalenthub,acceleratethepaceoftalentsinternationalization,strengthentheadjustmentefforttotalentstructures,enforcethemarketallocationmechanism,optimizethetalentecosystemandinnovatethesystemandmechanism.
简介:第五届拉丁格莱美大奖在美国城市洛杉矶揭晓,来自100多个国家特别是西班牙、葡萄牙的歌手汇聚在洛杉矶世纪广场,欢庆这个属于拉丁歌手的节日。西班牙歌手阿莱德罗·桑茨获得年度最佳专辑等四项大奖,成为此次颁奖典礼上的最大赢家。上届拉丁格莱美“最佳新人”奖的获得者大卫·比斯巴尔与美国流行女歌手杰西卡·辛普森首度合作,len为整场颁奖典礼带来第一首开场曲。WhenthelightscomeuponWednesdaysLatinGrammys,manymu-sicianslikeMexicanbandCafeTacuba,whoarelittleknownintheUnit-edStates,willcompetefortophonoursinashiningHollywoodcomingoutpartyfornewartists.Inashiftfromearlieryears,whenbigmainstreamsuperstarslikeRickyMartinsweptthetopcategories(项目),thefi...
简介:PLANTING“TALENTTREES”INVOGUEINYUNTAIVILLAGE¥//Inrecentyears,manypeasantsinthevillageofYuntaiinHunanprovincehavemadealong-term...
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简介:AsreportedbyChinaNewsNetwork,aplanwithabeautifulnameforimportingoverseastalentedexperts,TalentPeacockPlan,willascertainadequatehumanresourcesandpromoteindependentinnovationcapabilityofShenzhenwithintheGuangdongProvinceduringthe12thFive-YearPlan.TalentPeacockPlanisoneofthemeansthatShenzhenattemptstosetupthehugeinnovativeteamoftalents.ItisreportedthatShenzhenwillinsistonimporting,developingandgatheringinternationalinnovativehumanresourcestoestablishasuitableandadequatecityfor
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简介:AbstractBackground:Albuvirtide is a once-weekly injectable human immunodeficiency virus (HIV)-1 fusion inhibitor. We present interim data for a phase 3 trial assessing the safety and efficacy of albuvirtide plus lopinavir-ritonavir in HIV-1-infected adults already treated with antiretroviral drugs.Methods:We carried out a 48-week, randomized, controlled, open-label non-inferiority trial at 12 sites in China. Adults on the World Health Organization (WHO)-recommended first-line treatment for >6 months with a plasma viral load >1000 copies/mL were enrolled and randomly assigned (1:1) to receive albuvirtide (once weekly) plus ritonavir-boosted lopinavir (ABT group) or the WHO-recommended second-line treatment (NRTI group). The primary endpoint was the proportion of patients with a plasma viral load below 50 copies/mL at 48 weeks. Non-inferiority was prespecified with a margin of 12%.Results:At the time of analysis, week 24 data were available for 83 and 92 patients, and week 48 data were available for 46 and 50 patients in the albuvirtide and NRTI groups, respectively. At 48 weeks, 80.4% of patients in the ABT group and 66.0% of those in the NRTI group had HIV-1 RNA levels below 50 copies/mL, meeting the criteria for non-inferiority. For the per-protocol population, the superiority of albuvirtide over NRTI was demonstrated. The frequency of grade 3 to 4 adverse events was similar in the two groups; the most common adverse events were diarrhea, upper respiratory tract infections, and grade 3 to 4 increases in triglyceride concentration. Renal function was significantly more impaired at 12 weeks in the patients of the NRTI group who received tenofovir disoproxil fumarate than in those of the ABT group.Conclusions:The TALENT study is the first phase 3 trial of an injectable long-acting HIV drug. This interim analysis indicates that once-weekly albuvirtide in combination with ritonavir-boosted lopinavir is well tolerated and non-inferior to the WHO-recommended second-line regimen in patients with first-line treatment failure.Trial registration:ClinicalTrials.gov Identifier: NCT02369965; https://www.clinicaltrials.gov.Chinese Clinical Trial Registry No. ChiCTR-TRC-14004276; http://www.chictr.org.cn/enindex.aspx