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简介：the reasons for teaching writing to college students of English as a foreign language are not only that writing is a basic language skill but also that writing can 1) reinforce acquired language ability,It goes without saying that the demonstration of language ability relies more on the active or productive skills like speaking and writing. As for the two active or productive skills,writing is an especially effective way of further developing their language ability since it is such an active (compared with reading

简介：and to undertake practical writing. They should be able to write within 30 minutes a short composition of 120 words on a general topic or an outline. The composition should be basically complete in content,learning the present English writing requirements for college students in China is also critical to the improvement of writing instruction and practice. ,the writing requirements for undergraduate college English teaching are set at three levels

简介：<正>AttheinvitationofFriedrichEbertStiftung(FES)ofGermanyandCzechslovakForeignInstitute(CFI)oftheCzechRepublic,Mme.YanJunqi,Vice-ChairwomanoftheStandingCommitteeoftheNationalPeople’sCongress,ChairwomanoftheCentralCommitteeofChinaAssociationforPromotingDemocracyandPresidentofCAFIU

简介：ObjectiveTodetectthecellviabilityandtheexpressionsofstemcellsurfacemarkersafterchemotherapeuticdrugtreatment.MethodsWeobservedthecytotoxiceffectsofthreechemotherapeuticagents[epirubicin(Epi),fluorouracil(5-FU)andcyclophosphamide(Cyc)]inthreecelllines,andthecellviabilitiesafterremovedthesechemotherapeuticagents.ExpressionsofstemcellsurfacemarkersCD44,CD24,CD90,CD14andaldehydedehydrogenase1(ALDH1)inbreastcancercellswereanalyzedbyreal-timePCR.Theposthocanalysis(Tukey’stests)inconjunctionwithone-wayANOVAwasusedforstatisticalanalysis.ResultsTheinitialcytotoxicefficacywasmostnotable.Afterthetreatmentofthesametherapeuticagents,cellviabilitywasdecreasedby64.8%35.14%,32.25%inBT-483cells,66.4%,22.94%and45.88%inMDA-MB-231cells,97.1%,99.5%and76.4%inMCFcells.Thedifferencewassignificantcomparedwiththatbeforetreatment(P=0.000).However,theinhibitoryeffectswerediminishedafterchemotherapeuticagentwithdrawal.Cellviabilitieswereincreasedto167.9%,212.04%and188.66%inMDA-MB-231cellsat48hafterwithdrawal.At72hafterwithdrawal,cellviabilitywasincreasedwithasignificantdifferenceinthreecelllines(allPvalues=0.000).ExpressionsofCD44andALDH1weremostprevalentforMDA-MB-231,BT-483andMCF-7cells.ALDH1mRNAlevelwassignificanthigherinBT-483(HER-2overexpressioncellline)thanMDA-MB-231(triplenegativecellline)(P=0.012).CD14mRNAlevelinMCF-7cellsweresignificantlylowerthanthatinMDA-MB-231andBT-483(P=0.003,0.001).BT-483showedsignificantlyhigherlevelofCD44thanMDA-MB-231andMCF-7cellline(P=0.013,0.020),andnosignificantdifferencewasdetectedbetweenMDA-MB-231andMCF-7breastcancercells(P=0.955).CD90mRNAexpressionsweredetectedinMDA-MB-231cellsandMCF-7cells,butnotinBT-483cells.ConclusionSomemalignantcellscouldsurviveinvitroandbegintoproliferateagainbetweencyclesofchemotherapy.

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简介：Furthermore,breast-feedingwithoutvitaminDsupplementationcouldprolongthedeficiency,whichmightleadtoariskofserioushealthproblemslaterinlife,includingtype1diabetesanddecreasedbonedensity.'Craniotabes,thesofteningofskullbones,inotherwisenormalnewbornshaslargelybeenregardedasaphysiologicalconditionwithouttheneedfor