简介：赵本山，辽宁省铁岭市开原县人，现为铁岭市民间艺术团一级演员，中国曲艺家协会会员，辽宁省曲协副主席。自1998年小品《1＋1=？》登陆中央电视台后，其小品便成了一年一度央视春节晚会必不可缺的节目。随着由他主演的几十部影视和小品的热播，赵本山的名字走进了千家万户，成为备受全国观众瞩目的明星。现在让我们一起走近东方笑神——赵本山。

简介：Friedberg,LeeandZhao(FLZ)proposedamethodforeffectivelyevaluatingtheeigenenergiesandeigenwavefunctionsofquantumsystems.Inthiswork,westudyseveralspecialcasestoinvestigateapplicabilityofthemethod.Concretely,wecalculatetheground-stateeigenenergyoftheHellmannpotentialaswellastheCornellpotential,andalsoevaluatetheenergiesofthesystemswherelineartermisaddedtotheCoulombasaperturbation.Theresultsobtainedinthismethodhaveasurprisingagreementwiththetraditionalmethodorthenumericalresults.Sincetheresultsinthismethodhaveobviousanalyticitycomparedtothatinothermethods,andbecauseofthesimplicityforcalculationsthismethodcanbeappliedtosolvingtheSchrodingerequationandprovidesusabetterunderstandingofthephysicalessenceoftheconcernedsystems.ButmeanwhileapplicationsoftheFLZmethodarerestrictedatpresent,especiallyforcertainpotentialforms,butduetoitsobviousadvantages,itshouldbefurtherdeveloped.

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简介：PresidentZhaoJibinofChinaTitonggoestoJiangsutodosomesurveysandafterlisteningtotheworkingreportofJiangsuTietong,heinspectsthenetworkdevelopmentinNanjing,Suzhou,Changzhouandothercities.ZhaoJiBinemphasizesChinaTietongshouldbeonthewayof'enlargeprivatenetworkcoverageandmakegreatprogressinnetworkregionalization',makeeveryefforttolayasolid

简介：AbstractObjective:He-Zhao deficiency was originally described as a severe type of nonsyndromic hypodontia, and the causative gene locus was mapped to chromosome 10q11.2. The aim of this study was to identify potential genetic mutations that could cause He-Zhao deficiency.Methods:Patients with He-Zhao deficiency and their unaffected relatives of the large pedigree were investigated. The whole-exome sequencing using next-generation sequencing was employed to identify genetic variants. The data generated from the whole-exome sequencing using the Illumina Novaseq 6000 system were further analyzed by Burrows-Wheeler Aligner software, Sequence Alignment/Map tools and ANNOVAR tool. In vitro luciferase assay was used to investigate the effect of the detected mutation on gene expression. R environment was used to conduct t-tests. The study protocol was approved by the Research Ethics Committee of Bio-X Institutes, Shanghai Jiao Tong University (M2011004).Results:The exomes of five patients with He-Zhao deficiency and two of their unaffected relatives identified a mutation in PRKG1α as the molecular etiology of the disease. The variant c.-144 C>A of PRKG1 isoform 1 cosegregated with permanent tooth agenesis in 93 family members who were older than 12, at which time the primary teeth should have been replaced with permanent teeth. Functional studies suggested that the mutant allele promotes gene transcription by increasing its promoter activity.Conclusion:c.-144 C>A variant of PRKG1α involving odontoclast-associated root resorption is responsible for He-Zhao deficiency, unlike other forms of hypodontia, which typically involve odontoblast dysfunction.

简介：(January1998-December2013)Currentdevelopmentsinsedimentresearchcontinueataheadypace,andarereportedintheInternationalJournalofSedimentResearch(IJSR)atabout500pagesperyear.However,asofJanuary2014,amajorchangehasoccurred:after16years(January1998toDecember2013)asEditor-in-Chief,ProfessorZhao-YinWanghassteppeddownfromthehandlingofmanuscripts.

简介：Basedonthecovariantprolongationstructuretechnique,weconstructtheintegrablehigher-orderdeformationsofthe(2+1)-dimensionalHeisenbergferromagnetmodelandobtaintheirsu(2)×R(λ)prolongationstructures.ByassociatingthesedeformedmultidimensionalHeisenbergferromagnetmodelswiththemovingspacecurveinEuclideanspaceandusingtheHasimotofunction,wederivetheirgeometricalequivalentcounterparts,i.e.,higher-order(2+1)-dimensionalnonlinearSchrdingerequations.