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简介：摘要：随着网络规模的不断扩大和业务需求的多样化，传统的网络路由技术在高效性、可扩展性和灵活性等方面面临挑战。Segment Routing（SR）作为一种新型的网络路由技术，能够在满足不同业务需求的同时，保持网络架构的简单和高效。本文主要对Segment Routing技术进行了全面的分析与研究，包括其概念、原理、架构设计以及应用场景。

简介：Diexiearthquake(M7.5)in1933isagreateventthatoccurredattheeastborderofQinghai-XizangPlateauinthe20thcentury.Thereareobviouslydifferentopinionsabouttheshapeofisoseismallinesandthegeneticfaultofthisearthquke.Basedonthestudyofthenewlyfoundnorth-southtrendingactivefaultandgroundfissuresofDiexiearthquake,thispapertendstoholdthat,asthesouthwardextensionofMiujiangfault,thisnorth-southtrendingactivefaultmightbethegeneticfaultofthisevent.

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简介：BackgroundNon-ST-segmentelevationacutecoronarysyndrome(NSTE-ACS)isanacuteheartdiseasecausedbyincompleteocclusionofrelatedcoronaryarterieswithunstableatheroscleroticplaques.LeadaVRSTsegmentelevationandcTnIpositivearecloselycorrelatedtotheprognosisofNSTE-ACSpatients.However,therearefewstudiesapplyingthetwopredictorstoearlyriskstratificationinNSTE-ACSpatients.MethodTwohundredandfivecasesofNSTE-ACSpatientsfollowedupfor6monthsafterdischargewerereviewed.Allpatientsweredividedintofourgroups:GroupA-cTnInegativecombinedwithaVR-non-ST-segmentelevationgroup(100cases);GroupB-cTnInegativecombinedwithaVR-ST-segmentelevationgroup(31cases);GroupC-cTnIpositivecombinedwithaVR-non-ST-segmentelevationgroup(43cases);GroupD-cTnIpositivecombinedwithaVR-ST-segmentelevationgroup(31cases).Therewasnosignificantdifferenceingender,age,oldmyocardialinfarction,previousPCIhistory,hypertension,anddiabetesbetweenaVR-STelevationgroupandnoaVR-STelevationgroup.Themorbidityofleftmainorthree-vesselcoronaryarterydiseaseaswellasadversecardiovasculareventsinthefourgroupswereobservedandanalyzed.Results(i)Themorbidityofleftmainorthree-vesselcoronaryarterydiseasewashighestinGroupD(87.1%),andwasmarkedlyhigherinGroupB(41.9%)thanthatinGroupA(7%)orGroupC(9.3%);(ii)TheincidenceofadversecardiovasculareventswashighestinGroupD(77.4%),andwasmuchhigherinB(35.5%)ascomparedwiththattinGroupA(1%)orgroupC(7%).ConclusionElectrocardiographicleadaVRST-segmentelevationcombinedwithcTnIpositivehasanimportantclinicalvalueinpredictingtheprognosisofthepatientswithNSTE-ACS.

简介：ＡＮＥＷＰＬＡＮＡＲＢＯＯＬＥＡＮＯＰＥＲＡＴＩＯＮＡＬＧＯＲＩＴＨＭＢＡＳＥＤＯＮＬＩＮＥＳＥＧＭＥＮＴＳＯＲＴＩＮＧＭａＬｉｎ；ＤｕＸｉｑｉｎｇ；ＧｕａｎＲｏｎｇｃｈａｎｇＳＭＯＯＴＨＳＵＲＦＡＣＥＩＮＴＥＲＰＯＬＡＴＩＯＮＯＶＥＲＡＲＢＩＴＲＡ...

简介：Ourpreviousstudieshavehistomorphologicallyconfirmedthatnanofibrouspoly(3-hydroxybutyrateco-3-hydroxyvalerate)conduitcanbeusedtorepair30-mm-longsciaticnervedefects.However,therepaireffectsonratbehaviorsremainpoorlyunderstood.Inthisstudy,weusednanofibrouspoly(3-hydroxybutyrate-co-3-hydroxyvalerate)conduitandautologoussciaticnervetobridge30-mm-longratsciaticnervegaps.Within4monthsaftersurgery,ratsciaticnervefunctionalrecoverywasevaluatedpermonthbybehavioralanalyses,includingtoeoutangle,toespreadanalysis,walkingtrackanalysis,extensorposturalthrust,swimmingtest,open-fieldanalysisandnociceptivefunction.Resultsshowedthatratsciaticnervefunctionalrecoverywassimilarafternanofibrouspoly(3-hydroxybutyrate-co-3-hydroxyvalerate)conduitandautologousnervegrafting.Thesefindingssuggestthatnanofibrouspoly(3-hydroxybutyrate-co-3-hydroxyvalerate)conduitissuitableinuseforrepairoflong-segmentsciaticnervedefects.

简介：Furtherunderstandingofthepathphophisyology,advanceofthediagnosisinstrumentandrenovationoftheriskdelaminationstandardcanofferbettertherapyevidenceforthenon-ST-segmentelevationacutecoronarysyndrome(NSTE-ACS).Drugs,suchastrigeminyantiplateletdrug,prasugrel,fondaparinuxandbivalirudin,havebroughtgreatclinicaleffecttothehighriskpatients.SincetheresultoftheICTUStestannouncedandthedrugelutingballoondeveloped,wehavereachedthenewestrecognitionofhowtoselectachanceforinterventionandhowtopreventandcuretherestenosisofin-stent.

简介：Thispaperproposesalearning-basedmethodfortextdetectionandtextsegmentationinnaturalsceneimages.First,theinputimageisdecomposedintomultipleconnected-components(CCs)byNiblackclusteringalgorithm.ThenalltheCCsincludingtextCCsandnon-textCCsareverifiedontheirtextfeaturesbya2-stageclassificationmodule,wheremostnon-textCCsarediscardedbyanattentionalcascadeclassifierandremainingCCsarefurtherverifiedbyanSVM.AlltheacceptedCCsareoutputtoresultintextonlybinaryimage.Experimentswithmanyimagesindifferentscenesshowedsatisfactoryperformanceofourproposedmethod.

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简介：Inordertosolvetheproblemoflowprecisionandcomplicationofthree-dimensionalmodelingaboutmicro-segmentgear,onemethodofsettinguptheaccurate3Dmodelisintroduced.Atfirst,theequationoftheprofilecurveandthededendumtransitioncurveissetup,andthecoordinatesofthewholetoothprofilearecalculatedbytheprogramdevelopedbyDephisoftware.AndthenthedataofcoordinatesisimportedtoCatia,three-dimensionalmodelingcanbegotthroughtheoperationsofrotating,mirror,incisionandarray.Themethodusedinthispaperisaccurateandsimple,whichsuppliestheacademicbasisofCAEanalysisandvirtualdesignformicro-segmentgearandrelevantproducts.

简介：AIM:ToexplorethemolecularmechanismsinlensdevelopmentandthepathogenesisofPetersanomalyinSmad4defectivemice.METHODS:Le-CretransgenicmouselinewasemployedtoinactivateSmad4inthesurfaceectodermselectively.PathologicaltechniqueswereusedtorevealthemorphologicalchangesoftheanteriorsegmentinSmad4defectiveeye.ImmunohistochemicalstainingwasemployedtoobservetheexpressionofE-cadherin,Ncadherinanda-SMAinanteriorsegmentofSmad4defectivemiceandcontrolmiceatembryonic(E)day16.5.Real-timequantitativepolymerasechainreaction(qPCR)wasperformedtodetecttheexpressionofSnail,Zeb1,Zeb2andTwist2inlensofSmad4defectivemiceandcontrolmiceatE16.5.RESULTS:ConditionaldeletionofSmad4oneyesurfaceectodermresultedincorneaidysplasia,iridocornealangleclosure,corneolenticularadhesionsandcataractresemblingPetersanomaly.LossofSmad4functioninhibitedE-cadherinexpressioninthelensepitheliumcellsandcorneaiepitheliumcellsinSmad4defectiveeye.ExpressionofN-cadherinwasupregulatedincorneaiepitheliumandcorneaistroma.BothE-cadherinandN-cadherinweredown-regulatedatthefuturetrabecularmeshworkregioninmutanteye.TheqPCRresultsshowedthattheexpressionofTwist2wasincreasedsignificantlyinthemutantlens(P<0.01).CONCLUSION:Smad4isessentialtoeyedevelopmentandlikelyacandidatepathogenicgenetoPetersanomalybyregulatingepithelial-mesenchymaltransition.Twist2canberegulatedbySmad4andplaysanessentialroleinlensdevelopment.

简介：TheYuguangbasinisahalf-grabenbasininthebasin-rangetectoniczoneinnorthwestBeijing,locatedatthenorthernendoftheShanxigrabensystem,andtheYuguangbasinsouthernmarginalfault(YBSMF)controlstheformationofthisbasin.AlinearfaultescarpmenthasformedintheproluvialfanonthepiedmontfaultzoneoftheTangshankousegmentofYBSMF.Atrenchacrossthisescarpmentrevealsthreepaleo-earthquakeeventsontwoactivefaults.Onefaultrupturedatabout9kaforthefirsttime,andthenfaultedagainatabout7.3ka,causingtheformationandsynchronousactivityofanotherfault.Finally,theyfaultedforthethirdtime,butwecannotdeterminethefaultingtimeduetothelackofrelevantsurfacedeposition.Theaccumulativeverticaldisplacementofthesethreeeventsisabout8.1m.Weestimatethattheaveragerecurrenceperiodofthepiedmontfaultisabout1.7ka,andtheaveragesliprateofthepiedmontfaultisabout1.6mm/a.Wealsoestimatethereferencemagnitudeofeacheventaccordingtotheempiricalformula.

简介：Throughmechanicalanalysis,animprovedhydraulicmodelforannularcuttingstransportwithfoamwasestablishedforhorizontaldrilling.Basedonthetwocriticalinclinationangles,theentirewellwasdividedintothreesegments.TheBagnoldstress,generalizedpowerlawrheologicalmodelandmodifiedhinderedparticlesettlingvelocityinfoamfluidwereadoptedinthemodeltoimprovethesimulationaccuracy.Theproposedmodelallowsmoreprecisepredictionofcuttingstransportpropertyinthewholerangeofwellinclinationangle.Modelperformancewasexaminedviacasestudyandexperimentaldata.Simulationresultsgivenbythepropulsioniterationandtrial-and-errormethodagreewellwithin-situhorizontalwelldrillingpracticeforthecasestudy,andthecomparisonbetweenthemodelpredictionandCapo’sexperimentaldatashowssatisfactoryagreement.

简介：Asaresultoftheleft-lateralstrike-slippingoftheAltynTaghfaultinNeotectonicperiod,acontra-rotationalstructure,namelytheZhaobishanvortexstructure,hasdevelopedatthejunctureofthemainAltynTaghfaultandthenorthernfringefaultoftheQilianMountains.PreliminaryanalysisonthedeformationandevolutionoftheZhaobishanvortexstructure.Incombinationwiththepreviousdata,suggeststhatthetectonictransformbetweentheAltynTaghfaultandthenorthernfringefaultoftheQilianMountainsattributestothedeformationoftherotationalstructure.TheexistenceofaseriesofrotationalstructuresalongtheAltynTaghfaultandonthenortheasternedgeoftheQinghai-Xizang(Tibet)plateauindicatethatasthesubstanceinthenorthernQinghai-Xizang(Tibet)plateaumovesclockwisearoundtheeasterntectonicknotoftheHimalayas,rotationalstructuresbecometheprincipalmodeonthenorthernmarginalzoneofthePlateauoftransformingandabsorbingtectonicdeformation.

简介：ThelocationandlateQuaternaryactivityoftheCentral-NorthSegmentoftheTaihangMountainsPiedmontfaultzonehavebeenstudiedbyshallowseismicsurveyandcombineddrillexploration.OurresultsshowthattheBaoding-ShijiazhuangfaultandtheXushuifaultwereactiveinthelatePleistocene,butthesouthXushuifaulthasbeeninactivesincethelatePleistocene.Themaximummagnitudeofpotentialearthquakeofthefaultsis6.0.