简介：Diblockcopolymerscontainingpolystyrene(PSt)andpolybutylmethacrylate(PBMA)segmentsandrandomcopolymerofstyrene(St)andbutylmethacrylate(BMA)havebeenpreparedbyatomtransferradicalpolymerization(ATRP).DiblockcopolymersofBMAandStwithpredeterminedmolecularweight(1×10^4-6.5×10^4)andnarrowermolecularweightdistribution(1.25-1.5)wereobtained.Therandomcopolymercompositionsweredeterminedby^1HNMRspectroscopyandthereactivityratioswereevaluatedbytheextendedKelen-TudosmethodtobeYSt=0.91,YBMA=0.32.

简介：作为全球最在的赛车（赛道用）生产商，来自英国的Radical赛车在本次车展上的亮相是中国首次。尽管现场各车林立，但是它仍然以一种特别的姿态吸引众多关注。

简介：Thehighratioconcentrationhydroxylsolutionisproducedbystrongdischarge,andappliedtothepreventionofinvasivespeciesinshipballastwaterandredtide.Thispaperintroducestheplasmaprocessofhydroxylradicalproduction,theproductionprocessofhighratiohydroxylsolution,andtheapplicationtotreatingballastwaterandredtide.

简介：Thephotochemicalpropertiesofpolypropylviologen(PPrV)-cationexchangeableresincomplexeswerestudies.Thecolorofthesecomplexeschangedtobluewhenirradiatedbyamercurylamp.UVandESRstudiesindicatedthatanefficientviologenradicalaccumulationoccursinPPrV-resincomplexes.Anexplanationforthestablephotoinducedredicalaccumulationisproposed.

简介：ChildsNervSyst.2008Jun18.OBJECTIVES:Despiterevolutionarytechnicaladvancementinneuroimagingandoperativeneurosurgery,surgicalextirpationoffocalbrainstemglioma(BSG)remainssteepedincontroversy.Inthisstudy,weevaluatedourseniorauthor's(CT)surgical

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简介：Wehavesuccessfullysynthesized1-(2′-Phenyl)cycloproply1-2,3-epoxypropan-1-ol3,whichwillbeappliedtothekineticsstudyofoxiranylcarbinylradical.

简介：Thispaperevaluatestheutilizationoffreeradicalchemiluminescenceimagingandtomographicreconstructiontechniquestoassessadvancedinformationonreactingflows.Twodifferentlaboratoryflowconfigurationswereanalyzed,includingunvonfinednon-premizedjetflamemeasurementstoevaluateflamefuel/airmixingpatternsattheburner-portofatypicalglass-furnaceburner.Thesecondcasecharacterizedthereactionzoneofpremixedflameswithingasturbinecombustionchambers,basedonalaboratoryscalemodelofaleanprevaporizedpremixed(LPP)combustionchamber.Theanalysisshowsthatadvancedimagingdiagnosiscanprovidenewinformationonthecharacterizationofflamemixingandreactingphenomena.TheutilizationoflocalC2andCHchemiluminescencecanassessusefulinformationonthequalityofthecombustionprocess,whichcanbeusedtoimprovethedesignofpracticalcombustors.

简介：Theformationoffreeradicals（?）OHand（?）Hinanaturallyair-saturatedaqueoussolutionexposedtotherapeuticCWultrasoundatafrequencyof820kHzhasbeenconfirmedbyusingspintrapping5,5-dimethyl-1-pyrroline-1-oxide（DMPO）andelectronspinresonance（ESR）technique.Itissuggestedthattheseradicalsareformedduetothehightemperatureandpressureproducedbytheultrasonictransientcavitation.Thetransientcavitationthresholdisfoundat0.537-0.632W/cm2underasonicationtimeof3minutes.Withincreasingsoundintensitytheyieldoffreeradicals（?）OHraisesrapidlyattheintensityrangingfrom1—2W/cm2,andnolongerincreaseisobservedatabove3W/cm2.Thesoundintensity（I）dependenceoftheyieldof（?）OH（D）canbeapproximatelydescribedbyaregressionequation:D=8.1(I1/2-（Ic）1/2)1/2,whereIc=0.667W/cm2.UnderafixingsoundintensitytheyieldofOHincreasesmonotonouslywiththesonicationtime.

简介：Objective:Theaimofthepresentstudywastoconstructariskassessmentmodelwhichwastestedbydisease-freesurvival(DFS)ofesophagealcancerafterradicalsurgery.Methods:Atotalof164consecutiveesophagealcancerpatientswhohadundergoneradicalsurgerybetweenJanuary2005andDecember2006wereretrospectivelyanalyzed.Thecutpointofvalueatrisk(VaR)wasinferredbystem-and-leafplot,aswellasbyindependent-samplest-testforrecurrence-freetime,furtherconfirmedbycrosstabchi-squaretest,univariateanalysisandCoxregressionanalysisforDFS.Results:ThecutpointofVaRwas0.3onthebasisofourmodel.Therateofrecurrencewas30.3%(30/99)and52.3%(34/65)inVaR<0.3andVaR≥0.3(chi-squaretest,χ2=7.984,P=0.005),respectively.The1-,3-,and5-yearDFSofesophagealcancerafterradicalsurgerywas70.4%,48.7%,and45.3%,respectivelyinVaR≥0.3,whereas91.5%,75.8%,and67.3%,respectivelyinVaR<0.3(Log-ranktest,χ2=9.59,P=0.0020),andfurtherconfirmedbyCoxregressionanalysis[hazardratio=2.10,95%confidenceinterval(CI):1.2649-3.4751;P=0.0041].Conclusions:Themodelcouldbeappliedforintegratedassessmentofrecurrenceriskafterradicalsurgeryforesophagealcancer.

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简介：ＴＨＥＤＩＡＧＮＯＳＩＳＡＮＤＴＲＥＡＴＭＥＮＴＦＯＲＲＥＣＵＲＲＥＮＴＤＹＳＰＨＡＧＩＡＯＦＥＳＯＰＨＡＧＥＡＬＣＡＲＣＩＮＯＭＡＡＦＴＥＲＲＡＤＩＣＡＬＲＡＤＩＯＴＨＥＲＡＰＹＣｈｅｎＫｅｎｅｎｇ陈克能ＣｈｅｎｇＢａｎｇｃｈａｎｇ程邦昌Ｄｅｐａ...

简介：根据Ａｆ－Ａｇ自由基加聚反应的数量分布函数，导出凝胶点附近的渐进分布函数和高分子矩的表示式．进一步应用标度变换，得到了描述溶胶－凝胶相变的广义标度律，从而揭示了Ａｆ－Ａｇ自由基加聚的固化反应是一个相变过程．

简介：ＲＡＤＩＣＡＬ　ＰＯＬＹＭＥＲＩＺＡＴＩＯＮ　ＯＦ　ＶＩＮＹＬ　ＭＯＮＯＭＥＲ　ＩＮＩＴＩＡＴＥＤ　ＢＹ　ＣＥＲＩＣ　ＩＯＮ／ＴＡＲＴＡＲＩＣ　ＡＣＩＤＲＡＤＩＣＡＬＰＯＬＹＭＥＲＩＺＡＴＩＯＮＯＦＶＩＮＹＬＭＯＮＯＭＥＲＩＮＩＴＩＡＴＥＤＢＹＣＥＲ...

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简介：AbstractBackground:After radical hysterectomy for cervical cancer, the most common complication is lower urinary tract symptoms. Post-operatively, bladder capacity can alter bladder function for a prolonged period. This study aimed to identify factors affecting bladder storage function.Methods:A multicenter, retrospective cohort study was conducted. Information of patients with stages IA2 to IIB cervical cancer with urodynamic study results were retrospectively collected from nine hospitals between June 2013 and June 2018 according to the inclusion criteria. Demographic, surgical, and oncological data were collected. The univariate and multivariate logistic regression was used to identify clinical factors associated with bladder storage function.Results:Two hundred and three patients with cervical cancer had urodynamic testing post-operatively. Ninety-five (46.8%) patients were diagnosed with stress urinary incontinence (SUI). The incidence of low bladder compliance (LBC) was 23.2%. Twenty-seven (13.3%) patients showed detrusor overactivity (DO). Fifty-seven patients (28.1%) presented with a decreased maximum cystometric capacity (DMCC). The probability of composite bladder storage dysfunction was 68.0%. Multivariate analysis confirmed that laparoscopy represents a protective factor for SUI with an odds ratio of 0.498 (P = 0.034). Patients who underwent a nerve-sparing procedure were less odds to experience SUI (P = 0.014). A significant positive correlation between LBC and DO was observed (P < 0.001). A greater length of the resected vagina and chemoradiotherapy were common risk factors for LBC and DO, while radiotherapy exerted a stronger effect than chemotherapy. Additionally, patients who received chemoradiotherapy frequently developed a DMCC. The follow-up time was not correlated with bladder storage function.Conclusion:A nerve-sparing procedure without longer resected vagina is recommended for protecting the bladder storage function.

简介：AbstractBackground:Various prediction tools have been developed to predict biochemical recurrence (BCR) after radical prostatectomy (RP); however, few of the previous prediction tools used serum prostate-specific antigen (PSA) nadir after RP and maximum tumor diameter (MTD) at the same time. In this study, a nomogram incorporating MTD and PSA nadir was developed to predict BCR-free survival (BCRFS).Methods:A total of 337 patients who underwent RP between January 2010 and March 2017 were retrospectively enrolled in this study. The maximum diameter of the index lesion was measured on magnetic resonance imaging (MRI). Cox regression analysis was performed to evaluate independent predictors of BCR. A nomogram was subsequently developed for the prediction of BCRFS at 3 and 5 years after RP. Time-dependent receiver operating characteristic (ROC) curve and decision curve analyses were performed to identify the advantage of the new nomogram in comparison with the cancer of the prostate risk assessment post-surgical (CAPRA-S) score.Results:A novel nomogram was developed to predict BCR by including PSA nadir, MTD, Gleason score, surgical margin (SM), and seminal vesicle invasion (SVI), considering these variables were significantly associated with BCR in both univariate and multivariate analyses (P < 0.05). In addition, a basic model including Gleason score, SM, and SVI was developed and used as a control to assess the incremental predictive power of the new model. The concordance index of our model was slightly higher than CAPRA-S model (0.76 vs. 0.70, P = 0.02) and it was significantly higher than that of the basic model (0.76 vs. 0.66, P = 0.001). Time-dependent ROC curve and decision curve analyses also demonstrated the advantages of the new nomogram.Conclusions:PSA nadir after RP and MTD based on MRI before surgery are independent predictors of BCR. By incorporating PSA nadir and MTD into the conventional predictive model, our newly developed nomogram significantly improved the accuracy in predicting BCRFS after RP.

简介：Therapiesthatcomplementfreeradicalscavengingareanimportantapproachfortreatingaginginthebrain.Inthepresentstudy,twoformulationsofmoxaconemoxibustionwereappliedatacupointsZusanli(ST36)andXuanzhong(GB39),andatacupointsBaihui(DU20)andGuanyuan(RN4),inD-galactose-inducedsenilemice.TheresultsrevealedthatmoxaconemoxibustionimprovedtotalsuperoxidedismutaseandCu/Zn-superoxidedismutaseactivityinthehomogenatesofthecerebraltissue,aswellasamelioratingdeficitsinneuronalmorphologyandneuronaldensityinthecerebralcortexandhippocampalCA3.Moxaconemoxibustionalsoenhancedlearningandmemoryfunctionsofsenilemice.MoxaconemoxibustionatZusanli,Xuanzhong,BaihuiandGuanyuanacupointscanthusbeusedtocomplementfreeradicalscavengers,withefficacythatisequaltothatofelectroacupunctureatZusanliandXuanzhong,andsuperiortothatofnimodipinetreatment.

简介：通常，组织缺氧是在松驰的阴茎的一个正常生理的条件，被常规夜的勃起在cavernosal织物的坚持的组织缺氧由于neuropraxia结果在激进的前列腺切除术以后与自发、夜的勃起的正常可勃起的function.1缺乏在男人打断，它导致cavernosal的apoptosis和退化光滑的肌肉纤维。因此，克服组织缺氧被相信在neuropraxia期间起一个关键作用。真空的使用在阴茎康复的可勃起的设备(VED)据说是有效的并且可以阻止阴茎长度的损失。在VED使用以后的肉体的血被增加并且由动脉、静脉的血组成，由颜色Dopplersonography和血气体分析揭示了。类似的现象在否定压力创伤治疗(NPWT)被观察。然而，NPWT比VED，和hypoperfused采用一个更低的否定压力地区，响应邻近创伤边的否定压力增加，被观察。尽管如此，询问考虑理想的低于大气层的压力层次，行动的模式，和VED的治疗学的持续时间仍然保持未答复。而且，一个hypoperfused地区或PO2坡度是否在VED期间出现在阴茎，仍然保持不清楚治疗。在阴茎康复优化一个临床的VED协议，关于VED的机制的进一步的研究，在阴茎的不同部分的特别即时的PO2大小，应该被执行。

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