简介：Biometricstechnologieshavebeenaroundforquitesometimeandmanyhavebeendeployedfordifferentapplicationsallaroundtheworld,rangingfromsmallcompanies’timeandattendancesystemstoaccesscontrolsystemsfornuclearfacilities.Biometricsofferareliablesolutionfortheestablishmentofthedistinctivenessofidentitybasedon"whoanindividualis",ratherthanwhatheorsheknowsorcarries.BiometricSystemsautomaticallyverifyaperson’sidentitybasedonhis/heranatomicalandbehavioralcharacteristics.Biometrictraitsrepresentastrongandundeviatinglinkbetweenapersonandhis/heridentity,thesetraitscannotbeeasilylostorforgottenorfaked,sincebiometricsystemsrequiretheusertobepresentatthetimeofauthentication.Somebiometricsystemsaremorereliablethanothers,yettheyareneithersecurenoraccurate,allbiometricshavetheirstrengthsandweaknesses.Althoughsomeofthesesystemshaveshownreliabilityandsolidarity,workstillhastobedonetoimprovethequalityofservicetheyprovide.Presentedistheavailablestandingbiometricsystemsshowingtheirstrengthsandweaknessesandalsoemergingtechnologieswhichmayhavegreatbenefitsforsecurityapplicationsinthenearfuture.

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简介：Lowpowerconsumptionisamajorissueinnowadayselectronicssystems.ThistrendispushedbythedevelopmentofdatacenterrelatedtocloudservicesandsoontotheInternetofThings(IoT)deployment.Memoriesareoneofthemajorcontributorstopowerconsumption.However,thedevelopmentofemergingmemorytechnologiespavesthewaytolow-powerdesign,throughthepartialreplacementofthedynamicrandomaccessmemory(DRAM)withthenon-volatilestand-alonememoryinserversorwiththeembeddedordistributedemergingnon-volatilememoryinIoTobjects.Inthelattercase,non-volatileflip-flops(NVFFs)seemapromisingcandidatetoreplacetheretentionlatch.Indeed,IoTobjectspresentlongsleeptimeandNVFFsoffertosavedatainregisterswithzeropowerwhentheapplicationisidle.ThispapergivesanoverviewofNVFFarchitectureflavorsforvariousemergingmemorytechnologies.

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简介：CentralBusinessDistrict(CBD),aconceptthatwasfirstproposedbyU.S.scholarsinthe1920s,referstoabusinesscenterthatfunctionsasacommercialtrading,finan-cialinformation,culturalcenter,exhibitionandofficeareaallrolledintoone:aplacethatisthecenterofbusiness,thedrivingpowerofurbaneconomicdevelopmentandthesoulofacity.

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简介：Proteomicsisthestudyofproteinsandtheirinteractionsinacell.WiththecompletionoftheHumanGenomeProject,theemphasisisshiftingtotheproteincomplimentofthehumanorganism.Becauseproteomereflectsmoreaccuratelyonthedynamicstateofacell,tissue,ororganism,muchisexpectedfromproteomicstoyieldbetterdiseasemarkersfordiagnosisandtherapymonitoring.Theadventofproteomicstechnologiesforglobaldetectionandquantitationofproteinscreatesnewopportunitiesandchallengesforthoseseekingtogaingreaterunderstandingofdiseases.High-throughputproteomicstechnologiescombiningwithadvancedbioinformaticsareextensivelyusedtoidentifymolecularsignaturesofdiseasesbasedonproteinpathwaysandsignalingcascades.Massspectrometryplaysavitalroleinproteomicsandhasbecomeanindispensabletoolformolecularandcellularbiology.Whilethepotentialisgreat,manychallengesandissuesremaintobesolved,suchasmininglowabundantproteinsandintegrationofproteomicswithgenomicsandmetabolomicsdata.Nevertheless,proteomicsisthefoundationforconstructingandextractingusefulknowledgetobiomedicalresearch.Inthisreview,asnapshotofcontemporaryissuesinproteomicstechnologiesisdiscussed.

简介：Clinicalpracticeguidelines:ThechallengeofgradingClinicalpracticeguidelineshaveimprovedinqualityoverthepasttenyearsbyadheringtoafewbasicprinciples,suchasconductingthoroughsystematicreviewsofrelevantevidence,andgradingtherecommendationsandthequalityoftheunderlyingevidence．Thelargenumberofsystemsofmeasuringthequalityofevidenceandrecommendationsthathaveemergedare,however,confusing．Aninternationalgroupofguidelinedevelopers,systematicreviewers,andclinicalepidemiologists

简介：Source:MITTechnologyntroductionNotallbreakthroughsarecreatedequal.Somearrivemoreorlessasusablethings;othersmainlysetthestageforinnovationsthatemergelater,andwehavetoestimatewhenthatwillbe.Butwe’dbetthateveryoneofthemilestonesonthislistwillbeworthfollowinginthecomingyears.1.MagicLeap

简介：Marketbasedinitiativesformanagementofdegradingecosystemsandtheirserviceshavereceivedtheaddedattentionasoneoftheinnovativeresponsesintherecentyears.Thoseinitiativessuchasdirectandindirectpaymentforecosystemserviceslikepremiumforrainforesthoney,paymentbythepeopleatthelowerreachtothoseattheupperreachforthewatershedservicesetc.havedrawntheattentionofthedecisionmakersastheyhaveprovedtobefarmorecosteffective.Thispapersynthesizesthekeymessagesfromsomeofthecelebratedbutwellestablishedmarketforecosystemservicesacrosstheworld.Theecosystemservicesconsideredinthepaperarecar-bon,watershedservicesandbiodiversity.Wefindthatwhilecrediblevaluationofecosystemservicesforallservicesremainacriticalconcernbehindsettingupthepaymentmechanism,absentofnecessaryinstitutionalframeworkmayseriouslyunderminethisinnovativeresponseformanagementofecosystems.Inthepaper,necessaryinstitution-almechanismsenablingthemarketforthoseserviceshavebeensketchedout.Keymessagesfromthosecaseshavebeensynthesized.

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简介：ChinaandIndiaarethetwomostpopulouscountriesintheworldandbothhavethefastestgrowingeconomies.TheimplicationsofthisrelationshipandthesignificantgeopoliticalimpactithashadonAsiaandthewiderworldhaveattractedwidespreadattention.

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简介：AbstractImmunotherapy has become the mainstay for lung cancer treatment, providing sustained therapeutic responses and improved prognosis compared with those obtained with surgery, chemotherapy, radiotherapy, and targeted therapy. It has the potential for anti-tumor treatment and killing tumor cells by activating human immunity and has moved the targets of anti-cancer therapy from malignant tumor cells to immune cell subsets. Two kinds of immune checkpoints, cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) and programmed death-1 (PD-1)/programmed death ligand 1 (PD-L1), are the main targets of current immunotherapy in lung cancer. Despite the successful outcomes achieved by immune checkpoint inhibitors, a small portion of lung cancer patients remain unresponsive to checkpoint immunotherapy or may ultimately become resistant to these agents as a result of the complex immune modulatory network in the tumor microenvironment. Therefore, it is imperative to exploit novel immunotherapy targets to further expand the proportion of patients benefiting from immunotherapy. This review summarizes the molecular features, biological function, and clinical significance of several novel checkpoints that have important roles in lung cancer immune responses beyond the CTLA-4 and PD-1/PD-L1 axes, including the markers of co-inhibitory and co-stimulatory T lymphocyte pathways and inhibitory markers of macrophages and natural killer cells.

简介：从2009年年初开始,CA公司就多次拜访时任Computerware北亚区董事总经理的周浩良。目的是想邀请他担任CA大中华区副总裁。

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简介：The18monthssinceCHEP'2000haveseensignificantadvancesinGridcomputing,bothwithinandoutsidehighenergyphysics,Whileinearly2000,GridComputingwasanovelconceptthatmostCHEPattendeeswerebeingexposedtoforthefirsttime,wenowseeconsiderableconsensusonGridarchitecture,asolidandwidelyadopetedtechnologybase,majorfundinginitiatives,awidevarietyofprojectsdevelopingapplicationsandtechnologies,andmajordeploymentprojectsaimedatcreatingrobustGridinfrastructures,Iprovideasummaryofmajordevelopmentsandtrends,focusingontheGlobusopensourceGridsoftwareprojectandtheGriPhyNdatagridproject.

简介：Theelectricindustryisbeingtransformedfromacentralizednetworktoonethatislesscentralizedandallowsmoreconsumerinteractionintheformofasmartgrid.Thereisalsoastrongcommitmentbymostcountriestoreducegreenhousegasemissionsandglobalwarmingthroughtheuseofrenewableenergyresources.Thelocallyavailablerenewableresources,suchaswind,solar,tidal

简介：5月19日，美国FMCTechnologies和法国Technip两家公司宣布合并。此次交易的总价值高达130亿美元。预计，整个并购交易将于2017年年初完成。届时，这两家公司将分别占有合并后公司50％的股权。外界评论说，这是一个原油行业正在加速进行重组整合的信号。

简介：Thispaperexaminestherelativestrengthoffactorsinpredictingtheonsetofafinancialcrisisintheemergingmarketduringthe1990s.Weestimateaprobitmodelbasedonthequarterlydataof18countries.Theresultssuggestthatthemis-managementintheeconomyandbankingsystem,theshiftsintheinternationalconditionsandthedepthofcontagioneffectsarestronglyassociatedwiththepresenceofcrises.Someoftheresultsaresomewhatdifferentfromtheotherempiricalstudiesbasedonannualdata.Acarefulanalysisoftheprobabilitydistributionsshowedthattheresultswereclosetobeingcorrectinover90%ofthecases.