简介：AbstractBackground:Zoonoses are public health threats that cause severe damage worldwide. Zoonoses constitute a key indicator of One Health (OH) and the OH approach is being applied for zoonosis control programmes of zoonotic diseases. In a very recent study, we developed an evaluation system for OH performance through the global OH index (GOHI). This study applied the GOHI to evaluate OH performance for zoonoses in sub-Saharan Africa.Methods:The framework for the OH index on zoonoses (OHIZ) was constructed including five indicators, 15 subindicators and 28 datasets. Publicly available data were referenced to generate the OHIZ database which included both qualitative and quantitative indicators for all sub-Sahara African countries (n = 48). The GOHI algorithm was used to estimate scores for OHIZ. Indicator weights were calculated by adopting the fuzzy analytical hierarchy process.Results:Overall, five indicators associated with weights were generated as follows: source of infection (23.70%), route of transmission (25.31%), targeted population (19.09%), capacity building (16.77%), and outcomes/case studies (15.13%). Following the indicators, a total of 37 sub-Sahara African countries aligned with OHIZ validation, while 11 territories were excluded for unfit or missing data. The OHIZ average score of sub-Saharan Africa was estimated at 53.67/100. The highest score was 71.99 from South Africa, while the lowest score was 40.51 from Benin. It is also worth mentioning that Sub-Sahara African countries had high performance in many subindicators associated with zoonoses, e.g., surveillance and response, vector and reservoir interventions, and natural protected areas, which suggests that this region had a certain capacity in control and prevention or responses to zoonotic events.Conclusions:This study reveals that it is possible to perform OH evaluation for zoonoses in sub-Saharan Africa by OHIZ. Findings from this study provide preliminary research information in advancing knowledge of the evidenced risks to strengthen strategies for effective control of zoonoses and to support the prevention of zoonotic events.

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简介：AbstractHepatitis D virus (HDV) infection causes the most severe form of viral hepatitis with rapid progression to cirrhosis, hepatic decompensation, and hepatocellular carcinoma. Although discovered > 40 years ago, little attention has been paid to this pathogen from both scientific and public communities. However, effectively combating hepatitis D requires advanced scientific knowledge and joint efforts from multi-stakeholders. In this review, we emphasized the recent advances in HDV virology, epidemiology, clinical feature, treatment, and prevention. We not only highlighted the remaining challenges but also the opportunities that can move the field forward.

简介：AbstractBackground:The complete mesogastrium excision (CME) based on D2 radical gastrectomy is believed to significantly reduce the local-regional recurrence compared with D2 radical gastrectomy in advanced gastric cancer, and it is widely used in China. This study aimed to explore whether D2 + CME is superior to D2 on surgical outcomes during gastrectomy from Chinese data.Methods:Feasible studies comparing the D2 + CME (D2 + CME group) and D2 (D2 group) published up to March 2020 are searched from electronic databases. The data showing surgical and complication outcomes are extracted to be pooled and analyzed.Results:Fourteen records including 1352 patients were included. The D2 + CME group had a shorter mean operative time (weighted mean difference [WMD] = -16.72 min, 95% confidence interval [CI]: -26.56 to - 6.87 min, P < 0.001), lower mean blood loss (WMD = -39.08 mL, 95% CI: -49.94 to -28.21 mL, P < 0.001), higher mean number of retrieved lymph nodes (WMD = 2.13, 95% CI: 0.58-3.67, P = 0.007), shorter time to first flatus (WMD =-0.31 d, 95% CI: -0.53 to - 0.10 d, P = 0.005), and postoperative hospital days (WMD =-1.09, 95% CI: -1.92 to -0.25, P = 0.010) than the D2 group. Subgroup analysis suggested that the advantages from the D2 + CME group were obvious in traditional open radical gastrectomy, proximal gastrectomy, and distal gastrectomy compared with D2 group. The evaluations of post-operative complications showed that the patients who underwent D2 + CME had a lower incidence of post-operative complications than the patients who underwent D2 surgery alone (relative risk [RR] = 0.65, 95% CI: 0.45-0.87, P = 0.003). The D2 radical gastrectomy plus CME improved 3-year overall survival (OS) (RR = 1.16, 95% CI: 1.02-1.32, P = 0.020) and lowered the local recurrence rate (RR = 0.51, 95% CI: 0.28-0.94, P = 0.030). The patients undergoing laparoscopic surgery or total gastrectomy had more significant advantages compared between D2 + CME and D2 groups in 3-year OS.Conclusion:The data from China show that D2 radical gastrectomy plus CME are reliable procedures and safety compared to D2 radical gastrectomy with faster recovery, lower risk, and better prognosis.

简介：【摘要】目的 分析在对深静脉血栓形成患者进行早期诊断的过程中，D二聚体(D-D)与凝血因子联合检测的效果。方法 本次研究于本院随机抽取了31例2020年3月-2021年3月接诊的早期深静脉血栓形成患者设为研究组，另选同时期接收的健康体检患者31例设为参照组。两组患者均接受D二聚体与凝血因子联合检测，对比患者的检测结果。结果 研究组接受检测后患者D二聚体指标更高，凝血因子指标更低，对比差异明显（P＜0.05）。 结论 在进行早期深静脉血栓形成患者的诊断过程中，D二聚体联合凝血因子的检测能够充分显示患者在其的血浆指标变化，对深静脉血栓的形成进行提示，以便尽早采取有效的措施进行干预，适合于临床中应用。

简介：摘要：在二十一世纪的今天，零售行业迅速发展，全国零售企业数量如空中之星难以计量，纵观市场，强有力的零售企业却屈指可数。在此，谨以河南D零售企业为例（D超市洛阳老集店），深度分析地理位置，选址条件，经济发展水平，经营理念等因素对其发展的影响，并挖掘其不足之处，为零售业发展提供相关建议。

简介：摘要目的探讨食管鳞癌患者凝血四项、D-二聚体(D-D)水平与临床病理特征的相关性。方法抽取2020年6月至2021年6月周口市第一人民医院收治的80例食管癌患者作为研究对象，所有患者均接受食管癌根治术治疗，术后行组织病理检查，记录患者临床病理特征；检测患者入院时凝血四项及D-D水平，分析凝血四项、D-D水平与食管鳞癌患者临床病理特征的相关性。结果有淋巴结转移患者纤维蛋白原(FIB)、D-D水平高于无淋巴结转移者(P<0.05)；有远端转移患者活化部分凝血活酶时间(APTT)、凝血酶原时间(PT)短于无远端转移者，FIB、D-D水平高于无远端转移者(P<0.05)；低分化患者D-D高于中/高分化者(P<0.05)；经Logistic回归分析结果显示，FIB、D-D高表达与食管鳞癌患者淋巴结转移有关(P<0.05)；APTT短、PT短、FIB及D-D高表达与食管鳞癌患者远端转移有关(P<0.05)；D-D高表达与食管鳞癌患者低分化有关(P<0.05)。结论食管鳞癌患者凝血四项、D-D水平与淋巴结转移、远端转移、肿瘤分化程度等临床病理特征有关。

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简介：【摘要】目的：在冠心病诊断中联合进行超敏C反应蛋白(hs-CRP)、D-二聚体(D-D)、脂蛋白(a)[Lp(a)]等指标，并分析其应用价值。方法：选取2019年1月-2022年1月，在我院治疗的60例冠心病患者。根据临床分类标准，将其分为急性心肌梗死组（AMI）18例、不稳定心绞痛组（UAP）22例、稳定性心绞痛组（SAP）20例，同时选取50名健康体检者作为对照组。比较各组的检测结果。结果：冠心病各组患者的hs-CRP、Lp(a)、D-D 水平均明显高于对照组（P＜0.05），冠心病各组对比，AMI 组患者hs-CRP、Lp(a)、D-D 水平最高，其次为UAP 组患者，SAP 组患者最低，差异明显（P＜0.05）。结论：冠心病患者存在hs-CRP、Lp(a)、D-D 水平异常升高情况，且不同类型患者升高幅度也有明显差异，可作为临床诊断鉴别的重要依据。

简介：摘要：本文基于D公寓的财务风险问题进行探讨。分析了该公司筹资风险、投资风险、运营风险以及收益分配风险等方面的识别，并寻找出这些风险形成的成因。

简介：【摘要】：近些年来建筑行业不断发展，各类新技术不断涌现。3D打印再生混凝土逐渐地应用在建筑领域中，极大地推动了建筑领域的发展。尤其是3D打印再生混凝土技术有着高自动化、智能化、免模板的优势在建筑工程领域中出现了诸多的成功案例。在本文的研究中从3D打印再生混凝土的技术特点出发，结合相关的研究成果对3D打印再生混凝土设计技术进行研究与分析。

简介：摘要：3D打印技术具有制造复杂几何模型、加工过程操作简单、生产方式环保等优点，因此在加工制造业、工业设计、医疗、航天航空、军工等各个领域有着广泛应用。本文对3D打印技术及3D打印工艺原理及优缺点分析，同时展望3D技术未来的发展。

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简介：摘要： 3D打印技术又属于增材制造技术，可以在没有常规的加工机床等情况下，快速直接的实现零件的单件生产。本文论述了3D打印的原理及技术特点，详细展示了3D打印技术在汽车生产行业的实际使用，并对3D打印技术的未来发展进行了展望。

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简介：【摘要】目的：研究抗凝血酶Ⅲ、D－二聚体、纤维蛋白/纤维蛋白原降解产物与脑卒中的相关性。方法：选取本院接收的脑卒中患者42例，另选取同期健康体检者42例（2021年4月-2022年2月），将42例脑卒中患者设为观察组，42例健康体检者设为对照组，检测两组AT-Ⅲ、D－二聚体、FDP水平，比较治疗前后两组AT-Ⅲ、D－二聚体、FDP水平变化情况。结果：治疗前，相比于对照组，观察组FDP、D-D等指标明显更高（P

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简介：摘要：在保证线路运营的情况下，拆除既有线下原有结构物并重建，是既有线附近施工经常面临的问题。利用D型便梁来架空既有线具有封锁时间短、行车限速高、经济效益高等优点，是较为常用的施工方法之一。本文针对D型便梁在施工中的计算分析和施工方法进行探讨，为其他同类工程提供参考依据。

简介：摘要：解剖学是研究人体结构的学科，是医学学习的基础学科，掌握好解剖学的知识对于医生后续的临床实践非常重要。随着科技的发展，对于解剖学的学习出现很多好的工具，比如3D动画，虚拟实验室等，这些工具可以帮助学生快速了解解剖知识，可视化的明白一些知识，对于解剖学的发展意义重大。本篇文章就是阐述3D动画在解剖中应用，为推进解剖学的发展提供一些思路。

简介：摘要：在目标识别领域的数据融合技术当中，D-S证据理论被广泛应用，主要在于D-S证据理论可以有效的处理不确定信息。可有效处理复杂环境下引起的不确定问题，使其处理不确定信息时更加的高效。其缺点是在高冲突的证据发生时，得不到有效结果。本研究为探寻一种能够优化证据理论的方法，使其达到高冲突证据环境中，还能得到不偏离现实的有效融合结果的目的，研究并整理了大量相关文献，研究过程中发现有学者针对此方向有过探究，但效果不甚理想。基于此，本文经查阅大量国内外相关文献，为探寻一种解决高冲突证据问题的方法后分析和整理成为本篇综述。