简介:IntheirrecentpapersintheJournalofSportandHealthScienceonhamstringinjuriesinsprinting,~(1,2)andtheircorrespondingcommentariesoneachother'sresearch,3,4Yuetal.andLiuetal.proposeddifferentviewsofthemechanismsofmuscleinjuriesingeneral,andhamstringinjuriesinsprintingspecifically.WhileYuetal.~(1,3)arguedthatmuscleinjuriesareprimarily,ifnotexclusively,causedbymusclestrainmagnitudeineccentriccontractions,andthushamstringinjuriesoccurprimarilyat
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简介:Background:Theisometricsteady-statefollowingactivelengtheningisassociatedwithgreatertorqueproductionandloweractivation,asmeasuredbyelectromyographicactivity(EMG),incomparisonwithapurelyisometriccontraction(ISO)atthesamejointangle.Thisphenomenonistermedresidualforceenhancement(RFE).WhiletherehasbeenagreatdealofresearchinvestigatingthebasicmechanismsofRFE,littleworkhasbeenperformedtounderstandtheeverydayrelevanceofRFE.ThepurposeofthisstudywastoinvestigatewhetherneuromuscularcontrolstrategiesdifferbetweenISOandRFEbymeasuringtorquesteadinessofthehumanankleplantarflexors.Methods:FollowingISOmaximalvoluntarycontractionsin12males(25±4years),anactivelengtheningcontractionwasperformedat15°/sovera30°ankleexcursion,endingatthesamejointangleasISO(5°dorsiflexion;RFE).SurfaceEMGofthetibialisanteriorandsoleusmuscleswasrecordedduringalltasks.Torquesteadinesswasdeterminedasthestandarddeviation(SD)andcoefficientofvariation(CV)ofthetorquetraceintheISOandRFEconditionduringactivation-matching(20%and60%integratedEMG)andtorque-matching(20%and60%maximalvoluntarycontraction)experiments.Two-tailed,pairedttestswereused,withinsubjects,todeterminethepresenceofRFE/activationreduction(AR)andwhethertherewasadifferenceintorquesteadinessbetweenISOandRFEconditions.Results:Duringthemaximalandsubmaximalconditions,therewas5%-9%RFEwitha9%-11%AR(p〈0.05),respectively,withnodifferenceinantagonistcoactivationbetweenRFEandISO(p〉0.05).TherewerenodifferencesinSDandCVofthetorquetraceforthe20%and60%activation-matchingorthe60%andmaximaltorque-matchingtrialsineithertheRFEorISOcondition(p〉0.05).Duringthe20%torquematchingtrial,therewere~37%highervaluesforSDandCVintheRFEascomparedwiththeISOcondition(p〈0.05).Asignificantmoderate-to-strongnegativerelatio
简介:Neuromuscularactivityissuppressedduringmaximaleccentric(ECC)musclecontractioninuntrainedsubjectsowingtoattenuatedlevelsofcentralactivationandreducedspinalmotorneuron(MN)excitabilityindicatedbyreducedelectromyographysignalamplitude,diminishedevokedH-reflexresponses,increasedautogenicMNinhibition,anddecreasedexcitabilityindescendingcorticospinalmotorpathways.MaximumECCmuscleforcerecordedduringmaximalvoluntarycontractioncanbeincreasedbysuperimposedelectricalmusclestimulationonlyinuntrainedindividualsandnotintrainedstrengthathletes,indicatingthatthesuppressioninMNactivationismodifiablebyresistancetraining.Insupportofthisnotion,maximumECCmusclestrengthcanbeincreasedbyuseofheavy-loadresistancetrainingowingtoaremovedordiminishedsuppressioninneuromuscularactivity.Prolonged(weekstomonths)ofheavy-loadresistancetrainingresultsinincreasedH-reflexandV-waveresponsesduringmaximalECCmuscleactionsalongwithmarkedgainsinmaximalECCmusclestrength,indicatingincreasedexcitabilityofspinalMNs,decreasedpresynapticand/orpostsynapticMNinhibition,andelevateddescendingmotordrive.Notably,theuseofsupramaximalECCresistancetrainingcanleadtoselectivelyelevatedV-waveresponsesduringmaximalECCcontraction,demonstratingthatadaptivechangesinspinalcircuitryfunctionand/orgainsindescendingmotordrivecanbeachievedduringmaximalECCcontractioninresponsetoheavy-loadresistancetraining.
简介:Inthispaper,weintroducegeneralizedcyclicC-contractionsthroughpnumberofsubsetsofaprobabilisticmetricspaceandestablishtwofixedpointresultsforsuchcontractions.InourfirsttheoremweusetheHadzictypet-norm.InournexttheoremweuseLukasiewiczt-norm.OurresultsgeneralizetheresultsofChoudhuryandBhandari[11].Acontrolfunction[3]hasbeenutilizedinoursecondtheorem.Theresultsareillustratedwithsomeexamples.
简介:Prematureventricularcontraction(PVC)isthemostfrequentarrhythmiaencounteredinclinicalpractice.PVCmayoccurinhealthsubjects,whichisnotimminentlylife-threateningbutmayrequiretherapiestopreventfurtherproblems.So,thetimelyPVCrecognitionbecomesveryimportantfortheanalysisofelectrocardiogram(ECG),especiallyfortheremoteECGmonitoringusingmobilephones.Inthispaper,aconstructionmethodofpersonalizedECGtemplateandaPVCrecognitionmethodbasedontemplatematchingwerestudied.Firstly,weselected43ECGrecordingsfromtheMIT-BIHarrhythmiadatabase.Allrecordingsweredividedintotwodatasets(DS1fortrainingandDS2fortesting)andeachdatasetapproximatelycontainedthesameproportionofPVCbeats.Subsequently,foreachrecording(30min)inDS1,thefirst5minrecordingswereusedtoconstructthepersonalizedECGtemplateandthelast25minrecordingswereusedfortheR-wavepeaksdetectionandPVCrecognition,wherethetemplatematchingmethodwereused.ThevalidityoftheproposedmethodswastestedusingDS2.Theresultsshowedthat:1)highbeatdetectionaccuracywasachievedforbothPVCbeatsandnon-PVCbeats;2)thesensitivityandspecificityofPVCrecognitionwere99.11%and99.96%forthefirst5minrecordingsrespectively,99.17%and99.43%forthelast25minrecordingsrespectively.Alltheproposedmethodscanbereal-timeperformed,whichshowapromisingprospectfortheapplicationofECGmobilephones.
简介:Theuterinetetaniccontractionanduterinearterybloodflowreductionarepossiblereasonsforprimarydysmenorrhea(PD).Inthepresentstudy,weaimedtoevaluatetheuterinerelaxanteffectandtheinfluenceonuterinearterybloodvelocityofGe-GenDecoction(GGD),awell-knownChineseherbalformula.InfemaleICRmice,uterinecontractionwasinducedbyoxytocinexposurefollowingestradiolbenzoatepretreatment,andtheuterinearterybloodvelocitywasdetectedbyDopplerultrasound.HistopathologicalexaminationoftheuterinetissuesampleswereperformedbyH&Estaining.Exvivostudiesdemonstratedthatoxytocin,posteriorpituitary,oracetylcholineinducedcontractionsinisolatedmouseuterus.GGDinhibitedbothspontaneousandstimulatedcontractions.InvivostudydemonstratedthatGGDsignificantlyreducedoxytocin-inducedwrithingresponseswithamaximalinhibitionof87%.FurtherstudydemonstratedthatGGDnormalizedoxytocin-inducedabnormalitiesofprostaglandinsF2alpha(PGF2α)andCa2+inmice.Inaddition,injectionofoxytocininducedadecreaseinuterinearterybloodflowvelocity.PretreatmentwithGGDreversedtheoxytocinresponseonbloodflowvelocity.HistopathologicalexaminationshowedpretreatmentwithGGDalleviatedinflammationandedemaintheuteruswhencomparedwiththemodelgroup.BothexvivoandinvivoresultsindicatedthatGGDpossessedasignificantspasmolyticeffectonuterinetetaniccontractionaswellasimprovementonuterinearterybloodvelocitywhichmayinvolvePGF2αandCa2+signaling,suggestingthatGGDmayhaveaclinicpotentialinPDtherapy.
简介:Aseriesoftitlecompoundsaswellastheirprecursorsweresynthesizedbyprecursorroute.TheirPXRDpatternswerecharacterizedwithZrW2O8orZrMo2O8modelbyRietveldmethod.Thethermalcontractionsofthecompoundsweredeterminedaccordingtothevariable-temperaturePXRDdataandNTEcoefficientswerepresented.Thetwo-phasemixtureofZrW0.4Mo1.6O8wasalsoanalyzedindividually.