简介：介绍了聚环氧乙烷(PEO)的溶解热力学动平衡过程对PEO溶液特性的影响以及PEO用作助留剂的絮凝机理.PEO在吸附时,分子链的熵的损失会减弱PEO的吸附能力,损失过大时,会阻止PEO进行吸附.PEO经CF(Cofactor)改性的过程使得热函增加,当增加量超过损失值时,会促进PEO吸附.不同的CF对PEO进行改性的程度是不一致的,因此对PEO/CF的技术开发和应用具有广阔的前景.

简介：AbstractThe LIM domain only 1 (LMO1) gene belongs to the LMO family of genes that encodes a group of transcriptional cofactors. This group of transcriptional cofactors regulates gene transcription by acting as a key "connector" or "scaffold" in transcription complexes. All LMOs, including LMO1, are important players in the process of tumorigenesis. Unique biological features of LMO1 distinct from other LMO members, such as its tissue-specific expression patterns, interacting proteins, and transcriptional targets, have been increasingly recognized. Studies indicated that LMO1 plays a critical oncogenic role in various types of cancers, including T-cell acute lymphoblastic leukemia, neuroblastoma, gastric cancer, lung cancer, and prostate cancer. The molecular mechanisms underlying such functions of LMO1 have also been investigated, but they are currently far from being fully elucidated. Here, we focus on reviewing the current findings on the role of LMO1 in tumorigenesis, the mechanisms of its oncogenic action, and the mechanisms that drive its aberrant activation in cancers. We also briefly review its roles in the development process and non-cancer diseases. Finally, we discuss the remaining questions and future investigations required for promoting the translation of laboratory findings to clinical applications, including cancer diagnosis and treatment.