简介：小时候，我们总想长大，长大上天去看星星，去看月亮，去看整个世界。当然，最好能坐大气球周游世界!哈哈，读着这首诗，是不是感觉梦想不再遥远了呢？赶快拿起笔，来参与我们的互动练习，惊喜在等着你哦!

简介：Theballoon-basedcathetersareattractivefortheminimallyinvasiveproceduresbecausethesecatheterscanbeconfiguredtomatchrequirementsonsizeandshapefortheinteractionwiththesofttissue.Ananalyticalmechanicmodelisdevelopedforthedeformedballoontodeterminetheshapeoftheinflatedcatheter.Thebridgesalonglatitudinaldirectionshouldbehighstretchableduetothehighelongationalongthelatitudeoftheinflatablecatheter.Theseresultsagreewellwiththefiniteelementmethodwithoutanyparameterfitting.

简介：AIM:Todeterminethehypothesisthatinflatingtheballoonsintheduodenalpapilladetermineschangesinthebiochemicalmarkersofpancreatitis.METHODS:Fourgroupsofpigswereused:Grouppapilla(GP),theovertube’sballoonwasinflatedintheareaofthepapilla;GP+doubleballoonenteroscopy(GP+DBE),theovertube’sballoonwaskeptinflatedintheareaofthepapillafor20minbeforeaDBE;GroupDBE(GDBE),DBEwascarriedoutafterinsuringtheballoon’sinflationfarfromthepancreaticpapilla;andGroupcontrol(GC).Serumconcentrationsofamylase,lipaseandC-reactiveprotein(CRP)wereevaluated.Pancreaseswereprocessedforhistopathologyexamination.RESULTS:Mainchangesoccurred24haftertheprocedurecomparedwithbaselinelevels.AmylaselevelsincreasedsignificantlyinGP(59.2%higher)andweremoderatelyhigheringroupsGP+DBEandGDBE(22.7%and20%,respectively).LipaseincreasedinGPandGP+DBE,whereasithardlychangedinGDBEandinGC.CRPincreasedsignificantlyinGP,GP+DBEandGDBE,whilenochangeswerereportedforGC.NostatisticallysignificantdifferencebetweengroupsGPandGP+DBEwasfoundforthehistopathologicalfindings,exceptforvacuolizationandnecrosisofthepancreaticparenchymathatwashigherinGPthaninGP+DBE.CONCLUSION:Themanipulationoftheduodenalpapillabytheinflatedovertube’sballoonduringDBEcausespancreaticstructuraldamageandincreasedbiochemicalmarkersassociatedwithpancreatitis.

简介：这是YoonsangKim设计的MelodyBalloon音乐播放器，它会飞，相当于一个氦气气球。MelodyBalloon能漂在空中播放音乐——而你，可以悠闲地站在地球上，用一个套在手指上的遥控指环控制其起落和播放：可以直接让它漂在空中外放，也可以接上耳机独享。

简介：Wepresentthreecasesofself-expandablemetallicstent（SEMS）placementusingaballoonenteroscope（BE）anditsovertube（OT）formalignantobstructionofsurgicallyreconstructedintestine.ABEiseffectivefortheinsertionofanendoscopeintothedeepbowel.However,SEMSplacementisimpossiblethroughtheworkingchannel,becausetheworkingchannelofBEistoosmallandtoolongforthestentdevice.Therefore,weusedatechniqueinwhichtheBEisinsertedasfarasthestenoticarea;thereafter,theBEisremoved,leavingonlytheOT,andthenthestentisplacedbyinsertingthestentdevicethroughtheOT.Inthepresentthreecases,amodificationofthistechniqueresultedinthesuccessfulplacementoftheSEMSforobstructionofsurgicallyreconstructedintestine,andtheprocedureswereperformedwithoutseriouscomplications.Weconsiderthatthepresentprocedureisextremelyeffectiveasapalliativetreatmentfordistalbowelstenosis,suchasinthesurgicallyreconstructedintestine.

简介：ObjectivesToassesstheefficiencyandsafetyofdual-wireballoonangioplastysidebranchcombinedstentingthemainbranchinthetreatmentofcoronarybifurcationlesions.MethodsThisstudyincludedthirty-sixpatientswith41coronarybifurcationlesions.Selectivedual-wireballoonangioplastywasperformedinsidebranchand/orinmainbranch,andimplantationofstentswasperformedinmainbranchonly.Clinicaloutcomeandmajoradversecardiaceventswereobservedin-hospitalandfollow-up.ResultsSuccessrateofsidebranchdilatationbeforemainbranchstentingwas100%;mainbranchdirectstentingperformedin4cases;successmainbranchdilatationperformedintheother37cases;kissingtechniquewasperformedsuccessfullyin5cases,whichsidebranchwasjailedaftermainbranchstentingwithTIMIgrade0-2flow.NoQ-wavemyocardialinfarction,acuterevascularizationanddeathoccurredduringin-hospital.Clinicalfollow-upwasavailableinallpatients.NoQ-wavemyocardialinfarction,revascularizationanddeathoccurred,anginapectorisrecurredinthreepatients,releasedbystrengthendrugtreatment.ConclusionsDual-wireballoonangioplastysidebranchcombinedstentingthemainbranchissimple,safeandeffectiveforthetreatmentofcoronarybifurcationlesions.

简介：AbstractBackground:Massive bleeding is the main concern for the management of placenta percreta (PP). Intra-abdominal aortic balloon occlusion (IABO) is one method for pelvic devascularization, but the efficacy of IABO is uncertain. This study aims to investigate the outcomes of IABO in PP patients.Methods:We retrospectively reviewed the clinical data of PP cases from six tertiary centers in China between January 2011 and December 2015. PP cases with/without the use of IABO were analyzed. Propensity score matching analysis was performed to reduce the effect of selection bias. Postpartum hemorrhage (PPH) and the rate of hysterectomy, as well as neonatal outcomes, were analyzed.Results:One hundred and thirty-two matched pairs of patients were included in the final analysis. Compared with the control group, maternal outcomes, including PPH (68.9% vs. 87.9%, χ2= 13.984, P < 0.001), hysterectomy (8.3% vs. 65.2%, χ2= 91.672, P < 0.001), and repeated surgery (1.5% vs. 12.1%, χ2 = 11.686, P= 0.001) were significantly reduced in the IABO group. For neonatal outcomes, Apgar scores at 1 minute (8.67 ± 1.79 vs. 8.53 ± 1.68, t=-0.638, P= 0.947) and 5 minutes (9.43 ± 1.55 vs. 9.53 ± 1.26, t = 0.566, P = 0.293) were not significantly different between the two groups.Conclusions:IABO can significantly reduce blood loss, hysterectomies, and repeated surgeries. This procedure has not shown harmful effects on neonatal outcomes.

简介：Theratioofexpectationcrossingsofdielectricelastomerballoonexcitedbyrandompressureisanalyticallyevaluatedinthisletter.TheMooney–RivlinmodelisadoptedtodescribetheconstitutiverelationwhiletherandompressureisdescribedbyGaussianwhitenoise.Throughaspecifictransformation,thestochasticdifferentialequationsforthetotalenergyandphasearederived.Withtheapplicationofthestochasticaveraging,thesystemtotalenergyisthenapproximatedbyaone-dimensionaldiffusionprocess.SolvingtheassociatedFokker–Planck–Kolmogorov(FPK)equationyieldsthestationaryprobabilitydensityofthesystemtotalenergy.Theratioofexpectationcrossingsisthenderivedbasedonthejointstationaryprobabilitydensityofstretchratioanditsratioofchange.TheefficacyandaccuracyoftheproposedprocedureareverifiedbycomparingwiththeresultsfromMonteCarlosimulation(MCS).

简介：Sinceitsintroductionin1967,intra-aorticballoonpumping(IABP)hasbecomethemainstayinthemanagementofacuteleftventriculardysfunctioninthecriticalcaresetting.Typically,presentIABPsystemsareunabletoprovideconsistent,effectivecar-diacassistanceinthepresenceofarrhythmiasorrapidlychangingheartrates.Anew-generation,closedloop,fullyautomaticintra-aorticballoonpump(CL-IABP)

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简介：BackgroundThrombocytopeniaisacommoncomplicationofIABP.Untilnow,thereisnounifiedconclusionsabouttheincidence,characteristics,riskfactorsandtheprognosisofIABPrelatedthrombocytopenia.MethodsInthisstudy,thedataofpatientswithACSundergoingPCIandIABPwereretrospectivelyanalyzed.Allenrolledpatientsweredividedintothrombocytopeniagroupandnon-thrombocytopeniagroupaccordingtotheoccurrenceofthrombocytopeniaafterinsertionofIABP.Thebaselinedataofthetwogroupswerecompared,andthepossibleriskfactorsofthrombocytopeniaandtheirimpactonprognosiswereanalyzedbychi-squaretestandlogisticregressionanalysis.ResultsSixty-twopatientswereenrolledinthisstudy.TherateofIABPassociatedthrombocytopeniawas25.8%(16/62)ofallpatients.OlderagewasanindependentriskfactorofIABPassociatedthrombocytopenia(OR:3.625;95%confidenceinterval:1.016-12.935;P=0.047).TheincidenceofTIMIbleedingeventswashigherinthrombocytopeniagroup[75.0%(12/16)vs.43.5%(20/46),P=0.042].Therateofin-hospitaldeathwassimilarbetweenthetwogroups[18.8%(3/16)vs.17.4%(8/46),P=1.0].ConclusionIABPassociatedthrombocytopeniaoccursin25.8%ofpatientswithACSundergoingPCIandcorrelateswithincreasedTIMIbleedingevents.OlderagemaypredictIABPassociatedthrombocytopenia.

简介：backgroundIt'sestablishedthatAngiotensinⅡanditsreceptorsareinvolvedinintimalhyperplasiaafterballooninjuryandstentrestenosis.Recentevidencealsosuggeststhatstatinshavesomeanti-intimalhyperplasiaeffects.Inthisstudy,theeffectofRosuvastatinonexpressionofangiotensinⅡreceptorsinrataorticendotheliumafterballooninjuryisthereforeinvestigated.MethodsAll52WistarKyotoratswereestablishedtoaortainjurymodelsby2Fballooncatheter,thenwererandomlydividedintoshamoperationgroup,aortainjurygroupandRosuvastatin-treatmentgroup.After14days,theaorticspecimensoftheanimalswereharvestedandperformedimmunohistochemistryanddeterminationofmolecularbiology.ResultsTheresultsshowedthat(i)The14days-ballooninjuryinducedobviousintimathickening(P<0.01),however,thephenomenonwasreducedby14days-treatmentwithRosuvastatin(P<0.01).(ii)TheexpressionsofangiotentionⅡtypeⅠ(AT1)andtypeⅡ(AT2)receptormRNAandproteinweremarkedlyup-regulatedbytheballooninjury(P<0.01),after14days-treatmentwithRosuvastatin,theexpressionofAT1receptormRNAanditsproteinwasdecreased(P<0.01),buttheexpressionofAT2receptormRNAanditsproteinwasfurtherincreased(P<0.05).ConclusionInthisstudy,weobservedthattheballooninjuryinduced-intimathickeningwasreducedbyRosuvastatininrats,whichmightbelinkedwiththeregulationofexpressionofangiotensinⅡreceptors.

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简介：backgroundToinvestigatetheeffectofintra-aorticballoonpumping(IABP)onno-reflowphenomenoninprimarypercutaneouscoronaryintervention(PCI)forST-ElevationMyocardialInfarction(STEMI).MethodsClinicaldataof22acutemyocardialinfarctionpatientsafterPCIwithangiographicno-reflowphenomenonwereretrospectivelyanalyzedbetweenJanuary2006andDecember2009.12patientsunderwentIABP,other10patientsascontrolgroup.Weobserveddifferenceofcardiacstructure,brainnatriureticpeptide(BNP)andventricularsystolicfunctionbetweentwogroup,aswellascardiacinjurymarkers(MYO,CK-MB,cTnI)inbothgroupsonthedaysof1,2,3,5,7,10afterthedifferentinterventions.Inaddition,cardiacstructureandventricularsystolicfunctionincludingleftatriummedialdiameter(LAMD),leftventricularmedialdiameter(LVMD),leftventricularejectionfraction(LVEF)wasevaluatedafter10days,3months,6months.Finally,statisticswasusedtoanalysisthedata.ResultsTheseveralvasoactivesubstancesaswellascardiacinjurymarkersandLAMD,LVMD,LVEFof10days,3months,6monthsofIABPgroupweresignificantdifferencewithcontrolgroup(P<0.05).BNPtargetsofIABPgroupcomparedwiththecontrolgroupnosignificantdifference(P>0.05).ConclusionsIABPhaseffectsonprognosisinSTEMIpatientswhoperformedPCIwithangiographicno-reflowphenomenon,whichisconducivetorecoveryofheartfunction.

简介：ObjectiveTodeterminewhethersuccessfulvalvuloplastycausesanincreaseofmitralvalveareareserveinpatientswithmitralstenosis,isoproterenolstressechocardiographywasusedtocomparemitralvalveareaandhemodynamicchangesbetweenpre-andpost-valvuloplastyunderconditionsofincreasedcardiacwork.MethodsThirty-eightpatientswithpurerheumaticmitralstenosiswhohadreceivedsuccessfulpercutaneousballoonvalvuloplastyunderwentisoproterenolstressechocardiographypre-andpost-valvuloplasty.Mitralvalvearea(bydirectplanimetryoftwo-dimensionalechocardiography),meantransmitralpressuregradient(bycontinuous-waveDopplerechocardiography),andcardiacoutput(byM-modeechocardiography)weremeasuredatrestandunderisoproterenolstresstoachieveheartrateofdifferentstages.ResultsMitralvalvearea(0.91±0.28to1.87±0.23cm2,P<0.01),meantransmitralpressuregradient(12.5±6.3to3.9±1.9mmHg,P<0.01)andcardiacoutput(3.93±1.44to4

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简介：AbstractBackground:Endoscopic bariatric therapies can help address widening management gaps in obesity. Their ability to facilitate weight loss is largely tied to influences on appetite through perturbations of gastric emptying and accommodation. As these tools gain traction in obesity therapy, their physiologic underpinnings require exploration, which may enhance efficacy, tolerance, and patient-tailored care.Methods:We prospectively assessed consecutive subjects with fluid-filled intragastric balloons (IGBs) (n = 18) placed between October 2016 and June 2017 or underwent endoscopic sleeve gastroplasty (ESG) (n = 23) from March 2018 to June 2018. Patients underwent physiologic appraisal at 3 months with 13C-spirulina-based gastric emptying breath test to determine time to half emptying (T50), as well as maximum tolerated volume (MTV) of a standard nutrient drink test. Changes in T50 and MTV at 3 months were compared with percent total body weight loss (%TBWL) at 3 and 6 months using best-fit linear regression.Results:The change in T50 at 3 months correlated with %TBWL at 3 months for IGB (P = 0.01) and ESG (P = 0.01) but with greater impact on %TBWL in IGB compared to ESG (R2 = 0.42 vs. 0.26). Change in T50 at 3 months was predictive of weight loss at 6 months for IGB (P = 0.01) but not ESG (P = 0.11). ESG was associated with greater decrease in MTV compared to IGB (340.25 ± 297.97 mL vs. 183.00 ± 217.13 mL, P = 0.08), indicting an enhanced effect on satiation through decreased gastric accommodation. Changes in MTV at 3 months did not correlate with %TBWL for either IGB (P = 0.26) or ESG (P = 0.49) but trended toward significance for predicting %TBWL at 6 months for ESG (P = 0.06) but not IGB (P = 0.19).Conclusion:IGB and ESG both induce weight loss but likely through distinct gastric motor function phenotypes, and gastric emptying may predict future weight loss in patients with IGB.

简介：Theresultsoftwoballoonsoundingsduringthesummerandautumnof1993fromtheXiangheObservationStationarebeingutilizedinastudyofthetemporalandspatialdistributionoftheatmosphericaerosols.Theballoon,gondola,instrumentationandatmosphericconditionsduringtheobservationperiodaredescribed.Thetemporalandspatialcharacteristicsofaerosolconcentration,sizeratio,mixingratio,andsizedistributionforbothtroposphereandstrato-spherearepresentedandanalyzed.

简介：Objective:Toexplorethecausesoftheformationoftraumaticcarotid-cavernousfistulasandthetherapeuticeffectofdetachableballoonand/orcoilembolizationandthepreventionofitscomplications.Methods:FromOctober,1992toMarch,2002,17patientswithtraumaticcarotid-cavernousfistulasweretreatedwithdetachableballoonand/orcoilembolizationinourhospital.TheclinicaldataandimagingfeaturesofCT,MRandselectiveangiogramofthesepatientswereanalyzed.Results:Oneweekaftertreatmentwithembolization,theclinicalsymptomsofthe17patientswereremitted,andopticcacophony,nystagmus,exophthalmosanddropsyofconjunctivadisappeared.Twopatientsmanifestedsurgicalcomplications,onepatientdied.Sixteenpatientssurvived.Theywereallfollowedupformorethan2years,whichshowedonepatienthadhandicapinmovement,andinonepatientthesignsandsymptomsoftraumaticcarotid-cavernousfistulasreoccurred2monthsaftertreatment.Conclusions:Thedetachableballoonand/orcoilembolizationissafeandreliable.Itisagoodmethodtotreattraumaticcarotid-cavernousfistulas.

简介：AbstractBackgrounds:At present, there is no consensus on the induction methods in term pregnancy with borderline oligohydramnios. This study aimed to compare the effectiveness and pregnancy outcomes of labor induction with dinoprostone or single-balloon catheter (SBC) in term nulliparous women with borderline oligohydramnios.Methods:We conducted a retrospective cohort study from January 2016 to November 2018. During the study period, a total of 244 cases were enrolled. Of these, 103 cases were selected for induction using dinoprostone and 141 cases were selected for induction with SBC. The pregnancy outcomes between the two groups were compared. Primary outcomes were successful vaginal delivery rates. Secondary outcomes were maternal and neonatal adverse events. Multivariate logistic regression was used to assess the risk factors for vaginal delivery failure in the two groups.Results:The successful vaginal delivery rates were similar between the dinoprostone group and the SBC group (64.1% [66/103] vs. 59.6%, [84/141] P = 0.475), even after adjustment for potential confounding factors (adjusted odds ratio [aOR]: 1.07, 95% confidence interval [CI]: 0.57-2.00, P = 0.835). The incidence of intra-amniotic infection was lower in the dinoprostone group than in the SBC group (1.9% [2/103] vs. 7.8% [11/141], P < 0.001), but the presence of non-reassuring fetal heart rate was higher in the dinoprostone group than in the SBC group (12.6% [13/103] vs. 0.7%, [1/141] P < 0.001). Multivariate logistic regression showed that nuchal cord was a risk factor for vaginal delivery failure after induction with dinoprostone (aOR: 6.71, 95% CI: 1.96-22.95). There were three factors related to vaginal delivery failure after induction with SBC, namely gestational age (aOR: 1.51, 95% CI: 1.07-2.14), body mass index (BMI) >30 kg/m2 (aOR: 2.98, 95% CI: 1.10-8.02), and fetal weight >3500 g (aOR: 2.49, 95% CI: 1.12-5.50).Conclusions:Term nulliparous women with borderline oligohydramnios have similar successful vaginal delivery rates after induction with dinoprostone or SBC, with their advantages and disadvantages. In women with nuchal cord, the risk of vaginal delivery failure is increased if dinoprostone is used in the induction of labor. BMI >30 kg/m2, large gestational age, and estimated fetal weight >3500 g are risk factors for vaginal delivery failure after induction with SBC.