简介:摘要目的总结分析187例异位妊娠的发病和诊治情况,为预防和治疗提供依据。方法对我院2012年1月至2013年9月收治的187例异位妊娠手术确诊病例,对异位妊娠发生的部位、分型、出血量、手术方式等进行统计分析。结果187例异位妊娠病例中发生在输卵管间质部妊娠17例;峡部妊娠24例;壶腹部妊娠128例;伞端妊娠13例;卵巢妊娠2例;残角子宫妊娠1例;子宫后壁妊娠1例;左侧阔韧带妊娠1例;输卵管妊娠流产型114例;破裂61例;无流产破裂7例;出血量<1000ml有126例;>1000ml有49例。结论异位妊娠好发于输卵管壶腹部,以流产型多见,间质部、峡部妊娠多为破裂型,易引起腹腔内大出血,手术是主要治疗方法。加强计划生育宣教,采取适宜的避孕措施,要减少剖宫产率和流产率,减少IUD的使用,积极预防盆腔炎症,增强自我保护意识,最大限度降低异位妊娠的发生。
简介:摘要目的对药物性肝病患者进行分析,以提高对该病的认识,及早做出正确诊断和治疗。方法对2009年1月至2012年3月期间在我院就诊的187例诊断为药物性肝病的患者进行回顾性分析,并根据Maria药物性肝损伤评分标准进行评价。结果187例中Maria评分≥14分者127例。涉及药物频率由高到低依次为抗生素47.6%(89/187),中药及减肥茶16.6%(31/187),免疫抑制剂8.6%(16/187),心血管类药7.0%(13/187),解热抗炎药4.8%(9/187),抗甲状腺亢进及降糖药4.2%(8/187),性激素类药3.2%(6/187),其他8.0%(15/187)。临床分型肝细胞损伤型58.3%(109/187),胆汁淤积型25.6%(48/187),混合型16.1%(30/187)。80.2%(150/187)患者1个月内肝功能恢复正常,7%(13/187)患者肝功能异常持续半年以上,仅1例死亡。结论抗结核药及中草药引起的肝损伤最为常见,应引起临床医生重视。停用有关药物后大部分患者预后良好。
简介:目的:对中药引起的过敏反应进行统计分析.方法:收集1999~2001年间国内主要医药期刊报道的中药过敏反应187例,从性别、年龄、发生时间、用药途径、临床表现加以分析,并统计出较易发生过敏反应的前5位药物.结果:中药过敏反应的发生与性别、年龄无关,与用药途径有关,注射用药较易引发过敏反应(109例).过敏反应发生时间最短为用药后3min,最长为停药后7d,多数发生在用药过程中(167例).主要表现为皮肤反应(122例),其次为过敏性休克(26例),过敏性鼻炎(7例),过敏性哮喘(6例),过敏性紫癜(5例),药物热(17例)等.结论:中药不良反应中以过敏反应最为常见,应引起注意并及时预防.
简介:摘要目的分析不明原因发热(fever of unknown origin, FUO)患者的临床特点,总结FUO病因分布规律,以指导临床诊疗。方法纳入2015年1月至2016年12月于解放军陆军第八十二集团军医院住院且符合FUO诊断标准的187例患者,回顾性分析其临床资料,根据最终诊断将其分别归入感染性疾病组、结缔组织病组、肿瘤性疾病组、其他疾病组和未明确病因性疾病组,比较不同性别、年龄、热程FUO患者病因分布的差异。统计学方法采用χ2检验。结果187例FUO患者中,155例(82.9%)明确诊断,以感染性疾病为病因的患者为107例(57.2%),结缔组织病组为23例(12.3%),肿瘤性疾病组为15例(8.0%),其他疾病组为10例(5.3%),未明确病因性疾病组为32例(17.1%)。包含50余种疾病,位居前6位的疾病依次为布鲁菌病(20例)、结核分枝杆菌感染(12例,其中肺外结核8例)、尿路感染(9例)、败血症(8例)、成人斯蒂尔病(6例)、淋巴瘤(6例)。不同性别、年龄、热程FUO患者的病因分布存在差异。不同性别患者均以感染性疾病相关FUO为主;在肿瘤性疾病中,男10例,女5例,差异有统计学意义(χ2=3.986,P=0.046)。感染性疾病相关FUO在各年龄段的发病率均占首位;结缔组织病好发于壮年组[6.4%(12/187)]及中年组[4.3%(8/187)],肿瘤性疾病好发于老年组[3.7%(7/187)];不同年龄组在FUO病因分布上差异有统计学意义(χ2=23.427,P=0.024)。感染性疾病相关FUO患者的热程多<1个月,3个月以上热程患者多为非感染性疾病,感染性与非感染性疾病患者间的热程差异有统计学意义(χ2=43.393,P<0.01)。结论感染性疾病是诱发FUO的主要因素,其中布鲁菌病为感染性疾病中的首要病因,结核分枝杆菌感染为第2位病因,且以肺外结核为主。不同性别、年龄和疾病热程的FUO患者病因分布存在差异,应综合分析患者的诱发因素,制订符合患者疾病特征的诊疗计划。
简介:AbstractBackground:Joint dislocations significantly impact public health. However, a comprehensive study on the incidence, distribution, and risk factors for joint dislocations in China is lacking. We conducted the China National Joint Dislocation Study, which is a part of the China National Fracture Study conducted to obtain the national incidence and risk factors for traumatic fractures, and to investigate the incidence and risk factors for joint dislocations.Methods:For this national retrospective epidemiological study, 512,187 participants were recruited using stratified random sampling and probability-proportional-to-size method from January 19 to May 16, 2015. Participants who sustained joint dislocations of the trunk, arms, or legs (skull, sternum, and ribs being excluded) in 2014 were personally interviewed to obtain data on age, educational background, ethnic origin, occupation, geographic region, and urbanization degree. The joint-dislocation incidence was calculated based on age, sex, body site, and demographic factors. The risk factors for different groups were examined using multiple logistic regression.Results:One hundred and nineteen participants sustained 121 joint dislocations in 2014. The population-weighted incidence rate of joint dislocations of the trunk, arms, or legs was 0.22 (95% confidence interval [CI]: 0.16, 0.27) per 1000 population in 2014 (men, 0.27 [0.20, 0.34]; women, 0.16 [0.10, 0.23]). For all ages, previous dislocation history (male: OR 42.33, 95% confidence interval [CI]: 12.03–148.90; female: OR 54.43, 95% CI: 17.37–170.50) and alcohol consumption (male: OR 3.50, 95% CI: 1.49–8.22; female: OR 2.65, 95% CI: 1.08–6.50) were risk factors for joint dislocation. Sleeping less than 7 h/day was a risk factor for men. Compared with children, women aged ≥15 years (female 15–64 years: OR 0.16, 95% CI: 0.04–0.61; female ≥65 years: OR 0.06, 95% CI: 0.01–0.41) were less likely to sustain joint dislocations. Women with more than three children were at higher dislocation risk than women without children (OR 6.92, 95% CI: 1.18–40.78).Conclusions:The up-to-date data on joint dislocation incidence, distribution, and risk factors can be used as a reference for national healthcare, prevention, and management in China. Specific strategies for decreasing alcohol consumption and encouraging adequate sleeping hours should be developed to prevent or reduce dislocation incidents.Trial Registration:Chinese Clinical Trial Registry, ChiCTR-EPR-15005878.