学科分类
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2 个结果
  • 简介:Toevaluatetheinfluenceofosteoporosisonthemiddleandlateperiodsoffracturehealingprocessthroughobservingthehistomorphologicalchanges,honemineraldensityandbiomechanicalpropertiesinovariectomizedrats.Methods:Eighty-fourfemaleSDratsof4monthsoldwererandomlydividedintoosteoporosisgroupandshamoperationgroup,42ineach.Ratsinosteoporosisgroupwereperformedovariectomyoperationwhilethoseinshamoperationgroupweregivenshamoperation.Amidshafttibiafracturemodelwasestablished10weeksafterovariectomy.Tibiaswereharvested2,4,6,12,18weeksafterfractureforbonemineraldensity,histomorphologicalandbiomechanicalevaluation.Results:Comparedwiththeshamoperationgroup,callusbonemineraldensitywas12.8%,18.0%,17.0%lowerinosteoporosisgroup6,12,18weeksafterfracture,respectively(P<0.05);callusfailureloadwas24.3%,31.5%,26.6%,28.8%lowerinosteoporosisgroup,andcallusfailurestresswas23.9%,33.6%,19.1%,24.9%lowerinosteoporosisgroup4,6,12,18weeksafterfracture,respectively(P<0.05).Inosteoporosisgroup,endochondralboneformationwasdelayed,moreosteoclastcellscouldbeseenaroundthetrabecula,andthenewbonetrabeculaarrangedlooselyandirregularly.Conclusions:Osteoporosisinfluencesthemiddleandlateperiodsoffracturehealingintheratosteoporoticmodel.Theimpairmentisconsideredtobetheresultofcombinedeffectsofprolongedendochondralcalcification,highactivatedosteoclastcellandthedecelerationoftheincreaseinbonemineraldensity.

  • 标签: 康复治疗 骨质疏松 疾病中期 疾病晚期 小鼠 动物模型
  • 简介:客观:在中间的头部的窝底(EHMCFB)探索临床的特征,CT表明和创伤的额外的硬脑膜下血肿的起作用的指示。方法:有到2000年5月的从1997年1月的创伤的EHMCFB的14个盒子的一个总数回顾地被分析。结果:14个盒子,维持的12个盒子(85.7%)形成水塘的禅宗ge为被压的ambiens;11个盒子收到了操作的人,都被治好;3收到了保守治疗,2更好变得,1死了。结论:在创伤的EHMCFB,形式水塘变化ambiens容易发生。因此,如果显得日益增多地加重了,形式在水塘以后水塘换掉ambiensambiens正在被压,一早nd活跃操作必要、关键。

  • 标签: 颅窝底 硬膜外血肿 临床分析