简介：1.IntroductionWiththeincreaseinolderpopulationsworldwide1comesanincreasedhealthburdenrelatedtochronicdiseases.2–4Oneofthemostdisablingoftheseiskneeosteoarthritis（OA）,whichoccursinmillionsofolderadultswhosubsequentlylivewithjointpainandstiffness,leadingtochronicdisabilityandadiminishedqualityoflife.5,6EpidemiologicalevidenceshowsahigherprevalenceofOAinolderadultslivinginurbanandrural
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