简介：Hemocytecountsandphenoloxidase(PO)activitywereexaminedafterhemolymphbeingincubatedindopamine(DA),noradrenaline(NE)andserotonin(5-HT).Resultsshowedthatallthethreebiogenicamines(BAs)hadasignificantimpactontotalhemocytecount(THC),differentialhemocytecount(DHC),andintracelluarandextracelluarphenoloxidase(PO)activity.AmongtheseBas,DAhadthestrongesteffectontheaboveparameters,whereas5-HThadtheleasteffect.PreincubationwithD1receptorantagonistSCH23390,D2receptorantagonistSulpirideand1:1admixtureofthetwocouldsignificantlyinhibittheeffectofDAontheseparameters.SCH23390showedastrongerinhibitoryeffectthanSulpiride,andtheadmixtureexhibitedthestrongesteffect.Theseresultssuggestedthatthechangeofhemocytecountandactivationofprophenoloxidase(proPO)systeminLitopenaeusvan-nameihemocytecanberegulatedbyBAs,andDAmodulatesthetwoparametersviaitsreceptors.