简介：摘要组织工程化人工皮肤(TissueEngineeredArtificialSkin)是当今世界医学生物工程研究的热门领域.本文对DerwentInnovationIndex(DII)专利数据库收录的１９６８－２０１４年世界范围内申请的组织工程化人工皮肤技术专利进行了数据计量分析,给出了组织工程化人工皮肤专利的年度分布、地区分布、研发重点分布、机构分布等,揭示了已展现出明显优势的组织工程化人工皮肤技术的创新现状和发展趋势,所得到的结果可为这种新技术的研发决策提供支持与依据.研究发现,组织工程化人工皮肤技术近年来发展迅速,美国和中国对组织工程化人工皮肤领域研究资助力度持续加大,美国和日本在组织工程化人工皮肤研究领域占据主导地位.关键词组织工程化人工皮肤技术;创新现状;发展趋势;专利分析AStudyoftheTrendsofTissueEngineeredArtificialSkinTechnologyInnovationbasedonPatentAnalysisLibai－bhi１Zhouli－juan,２Haoyu－fang３Sunwen－yi４?Lizheng－wei５Huangzhi－cheng６(１．InstituteofFrontierMedicalScienceofJilinUniversity,Changchun,Jilin１３００２１,China;２．InstituteofScientificandTechnicalInformationofJilin,Changchun,Jilin１３００３３,China;３．AcademyofChineseMedicalSciencesofJilinProvince,Changchun,Jilin１３００２１,China;４．SchoolofPharmaceuticalSciences,Changchun,Jilin１３００２１,China;５．TheSecondHospitalofJiLinUniversity,Changchun,Jilin１３００４１,China;６．JilinCancerHospital,Changchun,Jilin１３００１２,China)AbstractTissueEngineeredArtificialSkinistheworld＇smostpopularareasofscientificResearch．ThepapermetrologicallyanalyzesthedataoftheTissueEngineeredArtificialSkintechnologypatents(１９６８—２０１４)collectedworldwidebytheDerwentInnovationIndexdatabase,andinvestigatesthevariationoftheanＧnualpatentamountintheperiod,thepatentamountofeachmajorcountry,thekeytechniquesofthepatents,andthepatentamountofeachmajorenterprise,andfinally,elaboratestheinnovationstatusanddevelopmenttrendsofthetechnology,theperformancesuperiorityofwhichisobviouslyemerging．Theresultsofthestudycanprovidethesupportandbasisfordecisiononthenewtechnologyresearch．Afteranalysis,theauthorfindsoutthatTissueEngineeredArtificialSkinTechnologydevelopsswiftlyinrecentyears,USandChinahadinvestedalargeamountofmoneyonTissueEngineeredArtificialSkin,USandJapanplayedadomＧinantrKoeleyownorTdisssueEngineeredArtificialSkin．TissueEngineeredArtificialSkin;Innovationstatus;Developmentwends;Patentanalysis中图分类号R３１８．１文献标识码A文章编号１００８－６３１５(２０１５)１０－００１７－０１