Role of Stable Isotopes in Life --Testing Isotopic Resonance Hypothesis

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摘要 Stableisotopesofmostimportantbiologicalelements,suchasC,H,NandO,affectlivingorganisms.Inrapidlygrowingspecies,deuteriumandtoalesserextentotherheavyisotopesreducethegrowthrate.Atleastfordeuteriumitisknownthatitsdepletionalsonegativelyimpactsthespeedofbiologicalprocesses.Asarule,livingorganisms'resist'changesintheirisotopicenvironment,preferringnaturalisotopicabundances.Thispreferencecouldbeduetoevolutionaryoptimization;anadditionaleffectcouldbeduetothepresenceofthe'isotopicreso-nance'.Theisotopicresonancephenomenonhasbeenlinkedtothechoiceofearliestaminoacids,andthusaffectedtheevolutionofgeneticcode.Totesttheisotopicresonancehypothesis,literaturedatawereanalyzedagainstquantitativeandqualitativepredictionsofthehypothesis.Fourstudiesprovidedfiveindependentdatasets,eachinverygoodquantitativeagreementwiththepredictions.Thus,theisotopicresonancehypothesisisnolongersimplyplausible;itcannowbedeemedlikely.Additionaltestingisneeded,however,beforefullacceptanceofthishypothesis.
机构地区 不详
出版日期 2011年01月11日(中国期刊网平台首次上网日期,不代表论文的发表时间)
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