摘要
Wedescribeanoveltechnique,lowsurfaceenergyGasExpansionMolding(GEM),tofabricatemicrobubblearraysinpolydimethylsiloxane(PDMS)whichareincorporatedintoparallelplateflowchambersandtestedincellsortingandmicrocellcultureapplications.Thisarchitectureconfersseveraloperationaladvantagesthatdistinguishthistechnologyapproachfromcurrentlyusedmethods.HereinwedescribetheGEMprocessandtheparametersthatareusedtocontrolmicrobubbleformationandaVacuum-AssistedCoating(VAC)processdevelopedtoselectivelyandspatiallyalterthePDMSsurfacechemistryinthewellsandonthemicrochannelsurface.WedescriberesultsfrommicroflowimagevisualizationstudiesconductedtoinvestigatefluidstreamsaboveandwithinmicrobubblewellsandconcludewithadiscussionofcellculturestudiesinPDMS.
出版日期
2008年04月14日(中国期刊网平台首次上网日期,不代表论文的发表时间)