生长抑素联合泮托拉唑治疗急性上消化道出血患者的临床观察

　　【摘要】 目的 探究生长抑素联合泮托拉唑治疗急性上消化道出血的临床疗效和安全性， 为临床医师选择合理用药方案提供参考。方法 84例急性上消化道出血患者， 按照治疗方式不同分为对照组和试验组， 每组 42例。对照组患者采用泮托拉唑治疗， 试验组患者采用生长抑素联合泮托拉唑治疗。比较两组患者的临床疗效、不良反应发生情况。结果 试验组患者临床总有效率为 92.86%， 显著高于对照组的 73.81%， 差异具有统计学意义（ P<0.05）。试验组患者不良反应发生率为 9.52%， 与对照组的 11.90%对比差异无统计学意义（ P>0.05）。结论 在急性上消化道出血患者治疗中， 采用生长抑素联合泮托拉唑治疗的止血效果理想， 且安全性较高， 值得借鉴。  　　【关键词】 急性上消化道出血 ;泮托拉唑 ;生长抑素 ;再出血  [Abstract] Objective To explore the clinical efficacy and safety of somatostatin combined with pantoprazole in the treatment of acute upper gastrointestinal hemorrhage, and to provide reference for clinicians to choose a reasonable drug regimen. Methods 84 patients with acute upper gastrointestinal hemorrhage were divided into control group and experimental group according to different treatment methods, 42 cases in each group. The control group was treated with pantoprazole, and the experimental group with somatostatin and pantoprazole. The clinical efficacy and adverse reactions of the two groups were compared. Results the total clinical effective rate of the experimental group was 92.86%, which was significantly higher than that of the control group (73.81%) (P < 0.05). The incidence of adverse reactions in the experimental group was 9.52%, and there was no significant difference between the experimental group and the control group (11.90%) (P > 0.05). Conclusion in the treatment of acute upper gastrointestinal hemorrhage, the effect of somatostatin combined with pantoprazole is ideal and safe, which is worth learning.

• 作者: 刘海燕
• 出处: 《中华医学信息导报》 2020年9期
• 分类: [医药卫生][临床医学]