摘要
【摘要】 目的 探究有创呼吸机治疗慢性阻塞性肺疾病（ COPD）合并Ⅱ型呼吸衰竭患者的临床疗效。方法 60例慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭患者， 根据治疗方法的不同将患者分为观察组和对照组， 各 30例。对照组患者给予常规疗法， 观察组患者给予常规疗法联合有创呼吸机治疗。对比分析两组患者的治疗效果。结果 治疗前， 两组患者的 pH值、动脉血氧分压（ PaO2）、动脉血二氧化碳分压（ PaCO2）比较， 差异均无统计学意义（ t=0.264、 0.369、 0.369， P>0.05）。治疗 24、 48 h后， 两组患者的 pH值比较， 差异均无统计学意义（ t=0.244、 0.375， P>0.05）；观察组患者的 PaO2高于对照组， 差异均具有统计学意义 （ t=2.711、 3.560， P<0.05） ； 观察组患者的 PaCO2低于对照组， 差异均具有统计学意义 （ t=4.913、 10.655， P<0.05）。结论 对慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭患者采用有创呼吸机治疗效果确切， 可促进患者血气指标的改善， 提高治疗效果， 值得在临床上推广应用。
【关键词】 有创呼吸机；慢性阻塞性肺疾病；Ⅱ型呼吸衰竭；动脉血二氧化碳分压；动脉血氧分压； pH值
[Abstract] Objective To explore the clinical effect of invasive ventilator in the treatment of chronic obstructive pulmonary disease (COPD) with type II respiratory failure. Methods 60 patients with chronic obstructive pulmonary disease and type II respiratory failure were divided into observation group and control group according to different treatment methods, 30 cases in each group. Patients in the observation group were treated with conventional therapy combined with invasive ventilator. The therapeutic effects of the two groups were compared. Results before treatment, there was no significant difference in pH, PaO2 and PaO2 between the two groups (t = 0.264, 0.369, 0.369, P > 0.05). After 24 and 48 hours of treatment, there was no significant difference in pH value between the two groups (t = 0.244, 0.375, P > 0.05); PaO2 of the observation group was higher than that of the control group, and the difference was statistically significant (t = 2.711, 3.560, P < 0.05); PaCO2 of the observation group was lower than that of the control group, and the difference was statistically significant (t = 4.913, 10.655, P < 0.05). Conclusion it is effective to use invasive ventilator in COPD patients with type Ⅱ respiratory failure. It can promote the improvement of blood gas index and improve the therapeutic effect. It is worthy of clinical application.
出版日期
2020年04月19日（中国期刊网平台首次上网日期，不代表论文的发表时间）
