Long-term outcomes in patients initially responsive to selective laser trabeculoplasty-中国期刊网

摘要 AIM:Todeterminethelong-termeffectsofselectivelasertrabeculoplasty(SLT)onintraocularpressure(IOP)andthenumberofmedicationsusedupto5yfollowingtreatmentinglaucomapatientsreceivingmaximallytoleratedmedicaltherapy(MTMT).·METHODS:TheWillsEyeHospitalGlaucomaResearchCenterretrospectivelyreviewedthechartsofglaucomapatientswhounderwentSLTafterreceivingMTMT.Eyesthatdidnotachievetheirtargetpressurewithin3mofollowingSLTwereexcludedfromthestudy.ChangesinmeanIOPandnumberofglaucomamedicationsusedwereanalyzedat1,3,and5yfollowingSLT.·RESULTS:Seventy-fiveeyesof67patientswereincludedinthestudy.FifteeneyesthatreceivedSLTfailedtoachievetheirtargetpressurewithin3moandwereexcludedfromthestudy.Theaveragefollow-uptimewas37.4mo(±14.4).MeanIOPwassignificantlyreduced1yaftertreatment(P=0.005).Itwasalsoreduced3,5yaftertreatmentwithoutreachingstatisticalsignificance(P=0.20andP=0.072,respectively).Therewasasignificantdecreaseinmeannumberofmedicationsused1,3,5yaftertreatment(P<0.001,P<0.001,andP=0.039,respectively).Inthespanof5y,2eyes(2.7%)underwentrepeatSLT,7eyes(9.3%)underwentglaucomasurgeryandanadditional3eyes(4.0%)underwentboth.·CONCLUSION:SLTsignificantlyreducedthenumberofglaucomamedicationsused5yfollowingtreatmentinglaucomapatientsreceivingMTMT.SLTmaydelayoperating-roomsurgery.

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Long-term outcomes in patients initially responsive to selective laser trabeculoplasty

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Long-term outcomes in patients initially responsive to selective laser trabeculoplasty

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