摘要
Laryngealsquamouscellcarcinoma(LSCC)remainsahighlymorbidandfataldisease.Historically,ithasbeenamodelexamplefororganpreservationandtreatmentstratificationparadigms.Unfortunately,survivalforLSCChasstagnatedoverthepastfewdecades.Astheeraofnext-generationsequencingandpersonalizedtreatmentforcancerapproaches,LSCCmaybeanidealdiseaseforconsiderationoffurthertreatmentstratificationandpersonalization.Here,wewilldiscusstheimportanthistoryofLSCCasamodelsystemfororganpreservation,uniqueandpotentiallytargetablegeneticsignaturesofLSCC,andmethodsforbringingstratified,personalizedtreatmentstrategiestothe21~(st)century.
出版日期
2016年01月11日(中国期刊网平台首次上网日期,不代表论文的发表时间)