Family Competition Pheromone Genetic Algorithm for Comparative Genome Assembly-中国期刊网

摘要 Genomeassemblyisaprerequisitestepforanalyzingnextgenerationsequencingdataandalsofarfrombeingsolved.Manyassemblytoolshavebeenproposedandusedextensively.Majorityofthemaimtoassemblesequencingreadsintocontigs;however,wefocusontheassemblyofcontigsintoscaffoldsinthispaper.Thisiscalledscaffolding,whichestimatestherelativeorderofthecontigsaswellasthesizeofthegapsbetweenthesecontigs.Pheromonetrail-basedgeneticalgorithm(PGA)waspreviouslyproposedandhaddecentperformanceaccordingtotheirpaper.Fromourpreviousstudy,wefoundthatfamilycompetitionmechanismingeneticalgorithmisabletofurtherimprovetheresults.Therefore,weproposefamilycompetitionpheromonegeneticalgorithm(FCPGA)anddemonstratetheimprovementoverPGA.

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Family Competition Pheromone Genetic Algorithm for Comparative Genome Assembly

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Family Competition Pheromone Genetic Algorithm for Comparative Genome Assembly

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